Geraniin Alleviates High‐Fat Diet‐Induced Atherosclerosis in ApoE−/− Mice [PDF]
Food Science &Nutrition, Volume 13, Issue 7, July 2025.GE treatment significantly reduced serum concentrations of lipids, oxidative stress damage, lipid deposition, and atherosclerotic plaque lesions in the ApoE−/− mice. A network pharmacology analysis indicated that the beneficial effect of GE treatment on atherosclerosis is closely related to its effect on oxidative stress, cell apoptosis, and ...
Yaoyao Xie +7 more
wiley +2 more sources
Mass Spectrometry‐Based Applications in Tannin Analytics: From Qualitative and Quantitative Analyses to Biological Activity [PDF]
Mass Spectrometry Reviews, Volume 45, Issue 1, Page 120-146, January/February 2026.ABSTRACT Tannins are widespread specialized plant metabolites that contribute significantly to the polyphenol content of plant‐based diets. Their effects on human and animal health vary depending on their structure, with potential benefits including antioxidative, antimicrobial, anthelmintic, and anticarcinogenic properties.
Marica T. Engström, Maarit Karonen
wiley +2 more sources
Geraniin Alleviates Mouse Laser‐Induced Choroidal Neovascularisation by Inhibiting Choroidal Endothelial Cell ACE2/Ang‐(1–7)/MasR/IL‐10 Pathway [PDF]
Journal of Cellular and Molecular Medicine, Volume 28, Issue 23, December 2024.ABSTRACT Anti‐vascular endothelial growth factor (VEGF) drugs suppress choroidal neovascularisation (CNV), thus improving vision. However, some patients may have a poor response or develop resistance to anti‐VEGF drugs. Geraniin (GE), a polyphenol isolated from an herb called Phyllanthus amarus, possesses anti‐angiogenic properties. This study aimed to
Hongyi Lu +7 more
wiley +2 more sources
In Vitro, In Vivo, and Clinical Trial Approaches to Investigate the Effects of Medicinal Plants on Burn Wound Healing: A Systematic Review [PDF]
International Wound Journal, Volume 22, Issue 11, November 2025.ABSTRACT Use of synthetic drugs for the treatment of burn wounds has decreased due to adverse effects, and they are gradually being replaced by compounds obtained from natural products, especially medicinal plants. This review focused on pre‐clinical and clinical studies examining the efficacy of medicinal plants in promoting burn wound healing.
Mahdi Bagheri +4 more
wiley +2 more sources
Therapeutic Potential of Acalypha wilkesiana in Type 2 Diabetes: A Review [PDF]
Journal of Diabetes Research, Volume 2025, Issue 1, 2025.Background Type 2 diabetes mellitus (T2DM) refers to a chronic metabolic disorder that results from insulin resistance, leading to impaired insulin action and uncontrolled plasma glucose levels. Acalypha wilkesiana is among medicinal plants that are ethnobotanically used in the management of T2DM.
Samuel Inshutiyimana +6 more
wiley +2 more sources
Aktivitas Antioksidan Dan Uji Iritasi Sediaan Masker Gell Peel-off Ekstrak Metanol Kulit Buah Rambutan (Nephelium Lappaceum L.) [PDF]
, 2016 Antioxidants are one of the free-radical scavengers. Methanol extract of rambutan peel containing phenolic compounds such as acids ellagat, corilagin and geraniin potential as antioxidants. Facial cosmetics are available in a variety of dosage forms,
Hadifa, H. U. (Hanuriza) +5 more
core +2 more sources
Herbal Remedies for Combating Irradiation: a Green Antiirradiation Approach [PDF]
, 2014 Plants play important roles in human life not only as suppliers of oxygen but also as a fundamental resource to sustain the human race on this earthly plane.
Choong, Y. S. +8 more
core +1 more source
Identification of the Plant Compound Geraniin as a Novel Hsp90 Inhibitor
PLoS ONE, 2013 Besides its function in normal cellular growth, the molecular chaperone heat shock protein 90 (Hsp90) binds to a large number of client proteins required for promoting cancer cell growth and/or survival. In an effort to discover new small molecules able to inhibit the Hsp90 ATPase and chaperoning activities, we screened, by a surface plasmon resonance ...
Vassallo, Antonio +4 more
openaire +5 more sources
Geraniin as a potential inhibitor of SARS-CoV-2 3CLpro
Natural Product Research, 2022 Geraniin is a polyphenolic compound first isolated from Geranium thunbergii. The major protease (Mpro), namely 3 C-like protease (3CLpro), of coronaviruses is considered an attractive drug target as it is essential for the processing and maturation of viral polyproteins.
Wen-Di, Yu +4 more
openaire +2 more sources
Production And Potency Of Local Rambutan At East Java AS A Candidate Phytopharmaca [PDF]
, 2013 Rambutan is a tropical fruit that grow well in Indonesia and the peel is considered as waste. Many researchers' showed that rambutan peel contains polyphenol that could be expected to avoid obesity.
Djati, M. S. (Muhammad) +3 more
core +2 more sources