Results 11 to 20 of about 1,084 (159)
Identification of the plant compound geraniin as a novel Hsp90 inhibitor. [PDF]
PLoS ONE, 2013 Besides its function in normal cellular growth, the molecular chaperone heat shock protein 90 (Hsp90) binds to a large number of client proteins required for promoting cancer cell growth and/or survival.
Antonio Vassallo +4 more
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Applied Sciences, 2020 The study outlined a standardized double emulsion method for simple poly(ethylene glycol)-block-poly(lactic-co-glycolic acid) (PEG-b-PLGA) nanoparticle (NP) synthesis.
Kogilavanee Devasvaran +6 more
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Efficacy of geraniin on dengue virus type-2 infected BALB/c mice [PDF]
Virology Journal, 2019 Background Dengue continues to be a major international public health concern. Despite that, there is no clinically approved antiviral for treatment of dengue virus (DENV) infections. In this study, geraniin extracted from the rind of Nephelium lappaceum
Siti Aisyah Abdul Ahmad +4 more
doaj +2 more sources
Geraniin supplementation increases human keratinocyte proliferation in serum-free culture
Universa Medicina, 2015 BACKGROUND Various products used in cellular therapy utilize tissue culture techniques requiring keratinocyte culture. An efficient and clinically acceptable keratinocyte culture system requires supplements with mitogenic activity.
Indra Kusuma, Restu Syamsul Hadi
doaj +2 more sources
Geraniin Protects High-Fat Diet-Induced Oxidative Stress in Sprague Dawley Rats [PDF]
Frontiers in Nutrition, 2018 Geraniin, a hydrolysable polyphenol derived from Nephelium lappaceum L. fruit rind, has been shown to possess significant antioxidant activity in vitro and recently been recognized for its therapeutic potential in metabolic syndrome.
Alexis Panny Y. S. Chung +4 more
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A novel effect of geraniin on OPG/RANKL signaling in osteoblasts
Brazilian Journal of Pharmaceutical Sciences, 2018 In this study, the effects of geraniin on osteoprotegerin/receptor activator of nuclear factor-κB ligand(OPG/RANKL) in regulating the proliferation of osteoblasts and suppression of osteoclast-like cells (OLC) in OLC-osteoblast co-cultured system in ...
Xiaochao Zhang +7 more
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Geraniin extracted from the rind of Nephelium lappaceum binds to dengue virus type-2 envelope protein and inhibits early stage of virus replication [PDF]
Virology Journal, 2017 Background The rapid rise and spread in dengue cases, together with the unavailability of safe vaccines and effective antiviral drugs, warrant the need to discover and develop novel anti-dengue treatments. In this study the antiviral activity of geraniin,
Siti Aisyah Abdul Ahmad +5 more
doaj +2 more sources
Applied Biological Chemistry, 2019 Repeated reflux of gastric acid and stomach contents into the esophagus leads to esophagus damage, including inflammation, ulcer, and hemorrhage in the epithelium.
Hyeon Hwa Nam +3 more
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Geraniin supplementation increases human keratinocyte proliferation in serum-free culture [PDF]
Universa Medicina, 2013 Background Various products used in cellular therapy utilize tissue culture techniques requiring keratinocyte culture. An efficient and clinically acceptable keratinocyte culture system requires supplements with mitogenic activity.
Indra Kusuma, Restu Syamsul Hadi
doaj +1 more source
Assessment of Wound-Healing Properties of Medicinal Plants: The Case of Phyllanthus muellerianus
Frontiers in Pharmacology, 2018 Phyllanthus muellerianus (Family Euphorbiaceae) is a shrub, which is widely distributed in West Africa and employed traditionally as a wound-healing agent especially in Ghana.
Yaw D. Boakye +5 more
doaj +2 more sources