Results 41 to 50 of about 527,784 (345)

Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation

FEBS Letters, EarlyView.
The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen, Zenon Toprakcioglu, Michele Vendruscolo   +2 more
wiley   +1 more source

Identification and comparative analysis of Identification and comparative analysis of microRNA in wheat (Triticum aestivum L.) callus derived from mature and immature embryos during in vitro culture

Frontiers in Plant Science, 2016
Feasible and efficient tissue culture plays an important role in plant genetic engineering. Wheat (Triticum aestivum L.) immature embryos (IMEs) are preferred for tissue culture to mature embryos (MEs) because IMEs easily generate embryogenic callus ...
Chu Zong Li, Chu Zong Li, Chu Zong Li, Chen Jun ying, Chen Jun ying, Chen Jun ying, Xu Hai Xia, Xu Hai Xia, Xu Hai Xia, Dong Zhong Dong, Dong Zhong Dong, Dong Zhong Dong, Chen Feng, Chen Feng, Chen Feng, Cui Dang Qun, Cui Dang Qun, Cui Dang Qun   +17 more
doaj   +1 more source

Influence of Abiotic Stresses on Morphophysiological Characteristics and Biological Value of Grain Sorghum bicolor (L.) Moench

International Journal of Plant Biology, 2023
Sorghum is the agricultural crop most adaptable to the effects of abiotic factors, able to tolerate prolonged soil and air droughts, changes in air temperature, insufficient precipitation, salinization, acidification of soils, and many others with the ...
Oksana Pavlovna Kibalnik, Irina Alexandrovna Sazonova, Yulia Valerievna Bochkareva, Vera Valerievna Bychkova, Dmitry Sergeevich Semin   +4 more
doaj   +1 more source

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

FEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li, Gerard van der Zon, Peter ten Dijke, Tong Shen   +3 more
wiley   +1 more source

Climate change and amphibians

Animal Biodiversity and Conservation, 2007
Cambio climático y anfibios Las historias vitales de los anfibios son sumamente sensibles a la temperatura y a la precipitación, y hay una clara evidencia que el reciente cambio climático ha tenido como resultado para algunas especies una anticipación ...
P. S. Corn
doaj   +3 more sources

Functional annotation and meta-analysis of maize transcriptomes reveal genes involved in biotic and abiotic stress

BMC Genomics
Background Environmental stress factors, such as biotic and abiotic stress, are becoming more common due to climate variability, significantly affecting global maize yield.
Rita K Hayford, Olivia C Haley, Ethalinda K Cannon, John L Portwood, Jack M Gardiner, Carson M Andorf, Margaret R Woodhouse   +6 more
doaj   +1 more source

Exogenous melatonin alleviates nicosulfuron toxicity by regulating the growth, photosynthetic capacity, and antioxidative defense of sweet corn seedlings

Photosynthetica
Improper use of nicosulfuron (NSF) may induce harmful effects on plants during weed control. Melatonin (MT) regulates photosynthetic and physiological processes in plants.
J.X. HUANG, Y.B. LIU, R. XIAO, T. YU, T. GUO, H.W. WANG, X.L. LV, X.N. LI, M. ZHU, F.H. LI   +9 more
doaj   +1 more source

Mapping Quantitative Trait Loci Associated With Resistance to Aflatoxin Accumulation in Maize Inbred Mp719

Frontiers in Microbiology, 2020
Aflatoxins are carcinogenic and toxic compounds produced principally by fungal species Aspergillus flavus (Link: Fries) and A. parasiticus (Speare), which are common contaminants of food and feed.
Erika D. Womack, W. Paul Williams, Gary L. Windham, Wenwei Xu, Wenwei Xu   +4 more
doaj   +1 more source

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

Ascorbic acid is involved in melatonin-induced salinity tolerance of maize (Zea mays L.) by regulating antioxidant and photosynthetic capacities

Photosynthetica
Melatonin (MT), an indole compound, can boost plant growth under abiotic stress conditions. This experiment aims to elucidate the synergistic effect of MT and ascorbic acid (AsA) in mitigating salinity stress by assessing the photosynthetic and ...
M. ZHU, T. GUO, Y.B. LIU, R. XIAO, T. YU, J.X. HUANG, W.L. DU, X.M. ZHONG, B. SONG, F.H. LI   +9 more
doaj   +1 more source