Results 31 to 40 of about 1,203,266 (307)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Identification and comparative analysis of Identification and comparative analysis of microRNA in wheat (Triticum aestivum L.) callus derived from mature and immature embryos during in vitro culture

Frontiers in Plant Science, 2016
Feasible and efficient tissue culture plays an important role in plant genetic engineering. Wheat (Triticum aestivum L.) immature embryos (IMEs) are preferred for tissue culture to mature embryos (MEs) because IMEs easily generate embryogenic callus ...
Chu Zong Li, Chu Zong Li, Chu Zong Li, Chen Jun ying, Chen Jun ying, Chen Jun ying, Xu Hai Xia, Xu Hai Xia, Xu Hai Xia, Dong Zhong Dong, Dong Zhong Dong, Dong Zhong Dong, Chen Feng, Chen Feng, Chen Feng, Cui Dang Qun, Cui Dang Qun, Cui Dang Qun   +17 more
doaj   +1 more source

Brown Mid-Rib Corn Population Trial [PDF]

, 2012
Brown mid-rib (BMR) corn hybrids are of interest to many growers in the Northeast who would like to maximize milk production on homegrown forage. BMR corn has a naturally-occurring genetic mutation that leads to less lignin in the stalk and makes corn ...
Cummings, Erica, Darby, Heather, Harwood, Hannah, Madden, Rosalie, Monahan, Susan   +4 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Corn Cropping Systems to Improve Economic and Environmental Health [PDF]

, 2014
In 2014, UVM Extension’s Northwest Crops & Soils Program initiated a trial at Borderview Research Farm in Alburgh, VT to assess the impact of corn cropping systems on overall health and productivity of the crop and soil.
Cummings, Erica, Darby, Heather, Monahan, Susan, Post, Julian, Ruhl, Lindsey, Zeigler, Sara   +5 more
core   +1 more source

Delaying Corn Rootworm Resistance to Bt Corn [PDF]

Journal of Economic Entomology, 2012
Transgenic crops producing Bacillus thuringiensis (Bt) toxins for insect control have been successful, but their efficacy is reduced when pests evolve resistance. To delay pest resistance to Bt crops, the U.S. Environmental Protection Agency (EPA) has required refuges of host plants that do not produce Bt toxins to promote survival of susceptible pests.
Bruce E, Tabashnik, Fred, Gould
openaire   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

PEMANFAATAN JAGUNG MANIS PADA SATU SET MENU HIDANGAN KONTINENTAL (STUFFED EGG WITH CORN, CORN BEEF STEAK, CORN CREAM CARAMEL) [PDF]

, 2012
Proyek Akhir ini bertujuan untuk 1) mengetahui formula, teknik olah, penyajian dan daya terima produk Stuffed Egg With Corn, 2) mengetahui formula, teknik olah, penyajian dan daya terima produk Corn Beef Steak, 3) mengetahui formula, teknik olah ...
Novi , Harmilia
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Climate change and amphibians

Animal Biodiversity and Conservation, 2007
Cambio climático y anfibios Las historias vitales de los anfibios son sumamente sensibles a la temperatura y a la precipitación, y hay una clara evidencia que el reciente cambio climático ha tenido como resultado para algunas especies una anticipación ...
P. S. Corn
doaj   +3 more sources