Results 141 to 150 of about 211,010 (368)

Multifunctional Biomimetic Nanotherapeutics for Anti‐Oxidative and Anti‐Inflammatory Synergistic Therapy of Corneal Neovascularization

open access: yesAggregate, EarlyView.
An anti‐inflammatory and antioxidant metal‐organic framework (MOF) nanoplatform was prepared via one‐pot self‐assembly. In vitro and in vivo studies demonstrated that the prepared MVPC nanoparticles can effectively scavenge overproduced reactive oxygen species at diseased sites, enhance IL‐10 secretion, and suppress VEGFA expression, offering a novel ...
Shundong Cai   +12 more
wiley   +1 more source

Inter-Municipal Cooperation – An Alternative Solution for The Amalgamation Projects?

open access: yesJournal of Danubian Studies and Research, 2017
Over the last three decades the Republic of Moldova has experienced several waves of reforms and counter-reforms. The governing political forces have implemented different reform strategies, mostly of them influenced by their political interest are ...
Sergiu Cornea
doaj  

Enhanced Synergistic Photothermal–Chemotherapy in Bacterial Keratitis Treatment Using Halogen‐Bonded Organic Frameworks (XOFs) Based on N⋯Br+⋯N Bonds

open access: yesAggregate, EarlyView.
Two novel XOFs based on [N···Br+···N] interactions were constructed. The XOFs(Br) deliver superior antibacterial properties compared with XOFs(I), due to a greater oxidation capability. Moreover, XOF(Br)‐TPPA, exhibiting greater hydrophilicity, shows superior antibacterial properties relative to XOF(Br)‐TPPE, which is weakly hydrophilic.
Zhennan Tian   +13 more
wiley   +1 more source

The Consequences of the Soviet Model of the Territorial Organization of Local Authorities in the Republic of Moldova: Until When?

open access: yesJournal of Danubian Studies and Research, 2015
In 1991, the Republic of Moldova became a sovereign state. By 1991, this country has had a Soviet administrative system which was characterized by excessive fragmentation of the territory.
Sergiu Cornea
doaj  

Lagrangian Shadows and Triangulated Categories [PDF]

open access: yesarXiv, 2018
Under certain assumptions (such as weak exacteness or monotonicity) we show that splitting Lagrangians through cobordism has an energy cost and, from this cost being smaller than certain explicit bounds, we deduce some strong forms of rigidity of Lagrangian intersections.
arxiv  

Costello Syndrome and Ophthalmologic Issues: Unveiling the Unseen

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Costello syndrome (CS) is an ultra‐rare condition belonging to the RASopathies, a group of disorders characterized by aberrant RAS/MAPK pathway signaling, which is involved in ocular development and in some eye pathologies. However, only a few studies assessing the ophthalmic features of individuals with CS are available.
Sofia Peschiaroli   +13 more
wiley   +1 more source

Astaxanthin ameliorates benzalkonium chloride–induced dry eye disease through suppressing inflammation and oxidative stress via Keap1‐Nrf2/HO‐1 signaling pathways

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The flowchart of this research. Abstract Background Dry eye disease (DED) predominantly results from elevated tear film osmolarity, which can not only cause ocular inconvenience but may lead to visual impairments, severely compromising patient well‐being and exerting substantial economic burdens as well.
Ziyu Liu   +9 more
wiley   +1 more source

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