Results 141 to 150 of about 246,104 (350)

Novel Intragenic Duplication of GATAD2B in a Patient With GAND

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The nucleosome remodeling and deacetylation (NuRD) complex is a major chromatin regulator and plays a critical role in regulating gene transcription, genome integrity, and cell cycle progression. Heterozygous variants in GATAD2B, a core NuRD component, have been reported to cause GATAD2B‐Associated Neurodevelopmental Disorder (GAND), an ...
Mari Mori   +9 more
wiley   +1 more source

Complications in Endoscopic Sinus Surgery: A TriNetX Network Analysis

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
Abstract Background The potential complications of endoscopic sinus surgery (ESS) remain a critical surgical consideration. This study aims to examine complication rates and identify trends in ESS‐related complications. Methods The TriNetX network was queried for patients undergoing ESS between 2005 and 2024.
Jakob L. Fischer   +8 more
wiley   +1 more source

The Demodex Expert Panel on Treatment and Eyelid Health (DEPTH) Consensus Regarding the Preferred Treatment for Demodex Blepharitis

open access: yesClinical Ophthalmology
Eric Donnenfeld,1 Kelly K Nichols,2 Brandon D Ayres,3 Marjan Farid,4 Preeya K Gupta,5,6 Richard Lyndon Lindstrom,7 Stephen Pflugfelder,8 Christopher E Starr,9 Nandini Venkateswaran,10 Ian Benjamin Gaddie,11 Paul M Karpecki,12 Cecelia Koetting,13 Selina ...
Donnenfeld E   +14 more
doaj  

A mouse model of lung ischemia–reperfusion injury with reversible left hilar entrapment

open access: yesAnimal Models and Experimental Medicine, EarlyView.
A Novel Reversible Left Hilar Entrapment Model for Mouse Lung Ischemia‐Reperfusion Injury with Visual Tracheal Intubation and Live Knot Technique. Abstract Lung ischemia–reperfusion injury (LIRI), an acute lung injury syndrome triggered by lung transplantation or distal organ ischemia, has long been a difficult and hot issue in clinical research.
GuangDong Weng   +4 more
wiley   +1 more source

General Public Interest: between Electoral Rhetoric and Administrative Actions

open access: yesJournal of Danubian Studies and Research, 2012
Traditionally, public administration is considered to be the operative side of government. Itis supposed to include all the activities involved in carrying out the policies of the elected officialsand some activities associated with the development of ...
Valentina Cornea
doaj  

Establishment of a novel alloxan‐induced rabbit model exhibiting unique diabetic retinal neuropathy features assessed via ERG + VEP

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Study workflow. Neuroretinal changes were observed in alloxan‐induced diabetic rabbits, while the retinal vasculature remained unaffected, indicating the successful establishment of a diabetic neuroretinal model. Abstract Background Diabetic retinal neuropathy (DRN) leads to significant visual impairment; however, no existing animal model fully ...
Xinlu Li   +9 more
wiley   +1 more source

Mass spectrometry in ocular drug research

open access: yesMass Spectrometry Reviews, EarlyView., 2023
Abstract Mass spectrometry (MS) has been proven as an excellent tool in ocular drug research allowing analyzes from small samples and low concentrations. This review begins with a short introduction to eye physiology and ocular pharmacokinetics and the relevance of advancing ophthalmic treatments.
Eva M. del Amo   +6 more
wiley   +1 more source

Multiple low dose streptozotocin‐induced diabetes as a model for studying autoimmune diabetes in humans

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Multiple low dose streptozotocin‐induced diabetes is a valuable animal model of diabetes type 1. It should be improved by further research on autoantigens, microbiota and mucosal immune cells from the gut, but also from other organs. Abstract The autoimmune response directed against pancreatic β cells is the most essential pathogenic process in type 1 ...
Ivan Koprivica   +4 more
wiley   +1 more source

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