Results 91 to 100 of about 182,932 (248)

Perceptions of Child Caregivers About Factors Influencing Childhood Corneal Blindness in a Rural Community in Southern Nigeria [PDF]

open access: yes, 2013
Objectives: Corneal scarring secondary to measles keratopathy and vitamin A deficiency is the leading cause of childhood blindness in Nigeria and can be prevented by simple primary health care measures.
Patel, D, Mbadugha, CA
core   +1 more source

Selective γ8 transmembrane α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid receptor regulatory protein negative allosteric modulators: Efficacy in preclinical antiseizure models

open access: yesEpilepsia, EarlyView.
Abstract Objective RAP‐219, a potent selective negative allosteric modulator (NAM) of α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid receptor (AMPAR) associated with γ8 transmembrane AMPAR regulatory protein (TARPγ8), is in phase 3 development for refractory focal epilepsy. This study was undertaken to assess efficacy and motor function following
Jose A. Matta   +5 more
wiley   +1 more source

Bio‐inspired vision: From principle, material architectures to system‐level integration

open access: yesFlexMat, EarlyView.
This review introduces the development and mechanism of electronic and ionic bio‐inspired vision devices respectively. Then, it explores the impact of structure on bio‐inspired visual performance from the scale of intrinsic materials and device. Finally, it concludes that only by combining advanced software and technology can more complex vision ...
Zewan Lin   +4 more
wiley   +1 more source

Femtosecond Laser-Assisted Surgery for Implantation of Bioengineered Corneal Stroma to Promote Corneal Regeneration

open access: yes, 2020
The femtosecond laser has achieved widespread use in ophthalmology owing to its ability to deliver focused high energy that is rapidly dissipated and thereby does not damage surrounding tissue outside the precise focal region.
Rafat, Mehrdad,   +3 more
core   +1 more source

A clinical study of etiology of corneal opacities

open access: yesMRIMS Journal of Health Sciences, 2015
Background: Corneal opacities are the common causes of corneal blindness. So, this study is to know the etiology of the corneal opacities. Objective: This study was to evaluate the etiology of corneal opacities, a common cause of corneal blindness ...
Srihari Atti   +3 more
doaj   +1 more source

Near visual function measured with a novel tablet application in patients with astigmatism

open access: yesClinical and Experimental Optometry, EarlyView., 2020
Clinical relevance While the clinical focus of performance metrics is traditionally based on visual acuity, research from the field of visual impairment has demonstrated that metrics such as reading speed and critical print size correlate much more strongly with subjective patient reported outcomes and assessed ability in real‐world tasks.
Ananya Datta   +8 more
wiley   +1 more source

LPCAT3 as a Potential Drug Target for Ultraviolet Radiation–Induced Cataract: Insights From Multiomics Analysis

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Ultraviolet B (UVB) radiation is a major risk factor for cataract development, but the molecular mechanisms underlying this process, particularly the involvement of regulated cell death pathways such as ferroptosis, remain unclear. Transcriptomic, proteomic, and metabolomic analyses were performed on lens tissues from UVB‐induced cataract rat ...
Fei Xu   +4 more
wiley   +1 more source

Visual Impairment and Blindness [PDF]

open access: yes, 2020
Blindness and vision impairment affect at least 2.2 billion people worldwide with most individuals having a preventable vision impairment. The majority of people with vision impairment are older than 50 years, however, vision loss can affect people of ...

core   +1 more source

Penetrating keratoplasty in eThekwini Health District 2011–2014

open access: yesAfrican Vision and Eye Health, 2015
Background: Penetrating keratoplasty (PK – corneal transplantation or full-thickness corneal graft) remains the primary sight-restoring procedure for corneal blindness.
Monawwar Khan   +2 more
doaj   +1 more source

Oral non‐steroidal anti‐inflammatory drugs do not delay corneal healing in dogs with spontaneous chronic corneal epithelial defects: A retrospective cohort of 186 ulcers

open access: yesVeterinary Record, EarlyView.
Abstract Background Oral non‐steroidal anti‐inflammatory drugs (NSAIDs) are commonly used for analgesia in dogs with spontaneous chronic corneal epithelial defects (SCCEDs). Topical NSAIDs can delay epithelialisation and promote stromal melting, but the safety of systemic NSAIDs in SCCEDs is unknown.
Kaitlyn Scheunemann   +2 more
wiley   +1 more source

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