Results 51 to 60 of about 182,932 (248)
Geographic distribution of the prevalence of infectious corneal blindness.
, 2014 Geographic distribution of the prevalence of infectious corneal blindness.
Lixin Xie (41999) +11 more
core +1 more source
Microbial keratitis in East Africa: why are the outcomes so poor? [PDF]
, 2011 PURPOSE: Microbial keratitis (MK) is a major cause of blindness in Africa. This study reports the epidemiology, causative organism, management and outcome of MK in people admitted to a large referral hospital in Northern Tanzania, and explores why the ...
Oates, Francesca +15 more
core +1 more source
Advanced Science, EarlyView.This study reveals the long‐elusive intracellular dissolution mechanism of carrier‐free nanomedicines. By utilizing peak‐shifted dual‐state emissive FRET nanoprobes (PDFNPs) that undergo a distinct ratiometric fluorescence peak shift upon disassembly, we achieve real‐time, quantitative tracking of dissolution kinetics in live cells.
Farsai Taemaitree +18 more
wiley +1 more source
Multivariate analysis of the risk factors for infectious corneal blindness.
, 2014 Multivariate analysis of the risk factors for infectious corneal blindness.
Lixin Xie (41999) +11 more
core +1 more source
BMC Public Health, 2019 Background Vitamin A deficiency (VAD) is of major public health significance; it is a risk factor for childhood deaths from diarrhoea and measles in low and middle-income countries and an important cause of preventable childhood blindness in low income ...
Ada E. Aghaji +2 more
doaj +1 more source
Artificial Cornea: Past, Current, and Future Directions
Frontiers in Medicine, 2021 Corneal diseases are a leading cause of blindness with an estimated 10 million patients diagnosed with bilateral corneal blindness worldwide. Corneal transplantation is highly successful in low-risk patients with corneal blindness but often fails those ...
Gráinne Holland +13 more
doaj +1 more source
TECTB Variants Reveal Tectorial Membrane Vulnerability in Dominant Non‐Syndromic Hearing Loss
Advanced Science, EarlyView.TECTB is a non‐collagenous protein of the tectorial membrane – an extracellular matrix of the cochlea. This study identifies dominant missense variants in TECTB linked to human hereditary deafness in two unrelated families. Genetically engineered mice homozygous for one of the variants are profoundly deaf, whereas heterozygous mice have normal hearing ...
Evan B. Hale +23 more
wiley +1 more source
Corneal Regeneration Using Gene Therapy Approaches
Cells, 2023 One of the most remarkable advancements in medical treatments of corneal diseases in recent decades has been corneal transplantation. However, corneal transplants, including lamellar strategies, have their own set of challenges, such as graft rejection ...
Subhradeep Sarkar +5 more
doaj +1 more source
Advanced Science, EarlyView.TGFBI deficiency elevates O‐GlcNAcylation, promoting the transcriptional activation of ADAMTS16 and OGT‐mediated post‐translational modification of ADAMTS16 at Ser1170. This leads to its stabilization and accumulation, driving chondrocyte metabolic disorders and senescent phenotypes, ultimately resulting in fibrocartilage dysfunction and TMJOA ...
Xin Liu +12 more
wiley +1 more source
Application of Novel Drugs for Corneal Cell Regeneration
Journal of Ophthalmology, 2018 Corneal transplantation has been the only treatment method for corneal blindness, which is the major cause of reversible blindness. However, despite the advancement of surgical techniques for corneal transplantation, demand for the surgery can never be ...
Sang Beom Han +3 more
doaj +1 more source