Results 81 to 90 of about 14,642 (226)

Corneal collagen crosslinking: from basic research to clinical application [PDF]

, 2010
Corneal collagen crosslinking is a promising new treatment of progressive corneal ectasia. Its clinical use has been rapidly increasing since it was originally introduced in 1997 as the first treatment that can improve biomechanical stability of ...
ADRIAN LUKENDA, JOSIP PAVAN, MARKO ]URKOVIĆ, SNJEŽANA KAŠTELAN   +3 more
core   +1 more source

Unlocking the potential of stimuli‐responsive liquid crystal polymer bio‐interfaces for adaptive cell modulation

Responsive Materials, EarlyView.
This Perspective discusses the potential of stimuli‐responsive liquid crystal polymer bio‐interfaces in modulating cell behavior as next generation dynamic artificial scaffolds. Unlike current artificial biomaterials that have static properties, LCPs offer fast, reversible, and spatially programmable deformation that reflects the dynamic properties of ...
Ruth M. C. Verbroekken, Burcu Gumuscu, Albert P. H. J. Schenning   +2 more
wiley   +1 more source

Nonlinear Optical Corneal Crosslinking, Mechanical Stiffening, and Corneal Flattening Using Amplified Femtosecond Pulses. [PDF]

, 2019
Purpose:We have shown that nonlinear optical corneal crosslinking (NLO CXL) and stiffening can be achieved in ex vivo rabbit corneas using an 80-MHz, 760-nm femtosecond (FS) laser, however the required power was beyond the American National Standard ...
Bradford, Samantha, Brown, Donald J, Jester, James V, Juhasz, Tibor, Kim, Sun Woong, Mikula, Eric, Xie, Yilu   +6 more
core  

Oxidized alginate hydrogels as niche environments for corneal epithelial cells [PDF]

, 2013
Chemical and biochemical modification of hydrogels is one strategy to create physiological constructs that maintain cell function. The aim of this study was to apply oxidised alginate hydrogels as a basis for development of a biomimetic niche for limbal ...
Ahmad, Araki-Sasaki, Balakrishnan, Balakrishnan, Balakrishnan, Boontheekul, Bouhadir, Cabane, Chen, Chen, Chen, Connon, Fonseca, Freeman, Grellier, Jeon, Kim, Koizumi, Lee, Lee, Li, Li, Liang, Mi, Mi, Moshaverinia, Pellegrini, Place, Sambu, Sun, Tamponnet, Thu, Veriter, Wang, Wright, Wright, Wright, Zhang, Zhang   +38 more
core   +2 more sources

Aniridia‐associated keratopathy: Clinical and molecular mechanisms of disease progression and emerging therapeutic targets

Acta Ophthalmologica, EarlyView.
Abstract Congenital aniridia is a rare genetic disorder primarily caused by pathogenic variants of the PAX6 gene. It leads to various panocular anomalies, including aniridia‐associated keratopathy (AAK). This review highlights recent insights into its pathogenesis, focusing on clinical staging, microstructural changes in the cornea and molecular ...
N. Szentmáry, S. Suiwal, M. Amini, F. N. Fries, A. Náray, L. Latta, Z. Li, S. Li, S. Liu, S. L. Hsu, S. Kundu, G. Tóth, S. Trusen, J. Zimmermann, B. Seitz, B. Käsmann‐Kellner, Z. Hoxha, A. Langenbucher, O. Stachs, M. Cortón‐Perez, K. Tory, A. Csorba, Z. Z. Nagy, M. C. Acosta, J. Gallar, M. Csidey, E. Maka, T. Stachon   +27 more
wiley   +1 more source

Unilateral progressive keratoconus associated with ipsilateral craniofacial fibrous dysplasia treated with corneal cross-linking

American Journal of Ophthalmology Case Reports
Purpose: The purpose of this study is to describe a case of unilateral keratoconus associated with ipsilateral craniofacial fibrous dysplasia and its subsequent management with corneal collagen cross-linking.
Alice C. Jiang, Maanasa Indaram
doaj   +1 more source

Genetic risk factors in Finnish patients with Fuchs endothelial corneal dystrophy

Acta Ophthalmologica, EarlyView.
Abstract Purpose To study the genetic risk factors of Fuchs endothelial corneal dystrophy (FECD) in the Finnish population using hospital‐based and large biobank cohorts. Methods We genotyped a cohort of 107 Finnish patients with FECD for the primary associated genetic risk factor, the TCF4 (CTG)>50 expansion, and studied their clinical phenotype.
Inka‐Tuulevi Vähämäki, Annamari T. Immonen, Joel T. Rämö, Aino M. Jaakkola, Kari Krootila, Maria Kaukonen, FinnGen, Aarno Palotie, Hannes Lohi, Tero T. Kivelä, Joni A. Turunen   +10 more
wiley   +1 more source

A comparative study of the elastic fibre system within the mouse and human cornea [PDF]

, 2018
The cornea relies on its organised extracellular matrix for maintaining transparency and biomechanical strength. Studies have identified an elastic fibre system within the human posterior cornea, thought to allow for slight deformations in response to ...
Feneck, Eleanor M., Lewis, Philip N., Meek, Keith M., Ralphs, Jim   +3 more
core   +2 more sources

Femtosecond Laser Created Corneal Allogenic Intrastromal Ring Segments for Keratoconus

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background To evaluate the clinical outcomes of femtosecond laser‐created corneal allogenic intrastromal ring segments (femto‐CAIRS) in keratoconic eyes using a newly described nomogram. Methods This retrospective case series recruited 85 eyes from 75 patients.
David J. Gunn, Rebecca A. Cox, Brendan Cronin   +2 more
wiley   +1 more source

Myoring implantation alone versus corneal collagen cross-linking following myoring implantation for management of keratoconus: 1 year follow up [PDF]

, 2016
Purpose: To compare combined MyoRing implantation with previously corneal collagen cross-linking (CXL- MyoRing) versus MyoRing implantation alone in patients with keratoconus.
Jadidi, Khosrow, Nobari, Sahar Mojaled, Villena Cepeda, Consuelo   +2 more
core   +1 more source