Results 61 to 70 of about 14,642 (226)

MEOX1 Coordinates Autocrine‐Paracrine Programs via SPHK1/S1P to Promote Lymph Node Metastasis in Ovarian Cancer

Advanced Science, EarlyView.
In ovarian cancer, MEOX1 activates the SPHK1/S1P pathway to promote both tumor progression and tumor–stroma crosstalk. MEOX1‐dependent signaling drives CAF activation, enhances VEGF‐C expression, and stimulates lymphangiogenesis, ultimately facilitating lymph node metastasis.
Jiajia Li, Xiuling Zhi, Qianhan Lin, Yating Sun, Yihua Sun, Zulimire Abudousalamu, Mengyang Xue, Chang Zheng, Xiaotian Li, Liangqing Yao, Mo Chen   +10 more
wiley   +1 more source

Еvaluate the Effectiveness of Accelerated Collagen Crosslinking in the Treatment of Corneal Endothelial Decompensation

Oftalʹmologiâ, 2020
The article discusses the effectiveness of accelerated collagen crosslinking in the treatment of patients with corneal diseases, a common basic pathogenetic link of which is endothelial corneal decompensation.
S. Yu. Astakhov, S. A. Novikov, S. S. Papanyan, I. A. Riks   +3 more
doaj   +1 more source

Research progress in animal models of dry eye disease: Types, mechanisms, and application prospects

Animal Models and Experimental Medicine, EarlyView.
Pivotal multifactorial animal models for translational dry eye disease research. Abstract Dry eye disease (DED) is a prevalent and complex multifactorial ocular surface disorder, leading to significant visual discomfort and diminished quality of life.
Jinshen Liu, Jiaqi Chen, Zhonghui Li, Jiamin Zhou, Hui Zhang, Yujia Yu, Feng Cheng, Jie Bao, Chunhan Feng, Xiangqu Yu, Zhao Xia, Rao Ding, Xiang Li   +12 more
wiley   +1 more source

The mechanical properties of amniotic membrane influence its effect as a biomaterial for ocular surface repair [PDF]

, 2012
The human amniotic membrane (AM) is a tissue of fetal origin and has proven to be clinically useful as a biomaterial in the management of various ocular surface disorders including corneal stem cell transplantation. However, its success rate displays a
Alcock, Simon, Chen, Bo, Connon, Che, Foster, James, Hamley, Ian, Jones, Roanne R., Mi, Shengli   +6 more
core   +1 more source

Natural Aging of Biomaterials in Ambient and Physiological Environments

Advanced NanoBiomed Research, EarlyView.
Biomaterials used in biomedical applications can change their physical properties over time, even under ambient and physiological conditions. This review highlights key studies on the natural aging of materials ranging from soft hydrogels to metals and ceramics, emphasizing how time‐dependent changes influence function and performance.
Shuyu Zhang, Anne E. Staples
wiley   +1 more source

Riboflavin/UVA collagen cross-linking-induced changes in normal and keratoconus corneal stroma.

PLoS ONE, 2011
PurposeTo determine the effect of Ultraviolet-A collagen cross-linking with hypo-osmolar and iso-osmolar riboflavin solutions on stromal collagen ultrastructure in normal and keratoconus ex vivo human corneas.MethodsUsing small-angle X-ray scattering ...
Sally Hayes, Craig Boote, Christina S Kamma-Lorger, Madhavan S Rajan, Jonathan Harris, Erin Dooley, Nicholas Hawksworth, Jennifer Hiller, Nick J Terill, Farhad Hafezi, Arun K Brahma, Andrew J Quantock, Keith M Meek   +12 more
doaj   +1 more source

Corneal collagen cross-linking in patients with keratoconus associated with dry eye

Journal of the Egyptian Ophthalmological Society, 2017
Purpose The aim of this study was to assess the safety and efficacy of corneal collagen cross-linking in keratoconus associated with dry eye. Patients and methods This study included 35 eyes of 29 patients diagnosed as having keratoconus associated with ...
Tamer H El-Sersy
doaj   +1 more source

Delivery of riboflavin-5’-monophosphate into the cornea: can liposomes provide any enhancement effects? [PDF]

, 2017
Keratoconus is a progressive condition caused by the thinning of the cornea, which eventually deforms the front surface of the eye into a cone shape leading to ghosting, multiple images, glare and several other vision problems.
Ahmad, Anyakora, Bender, Benelli, Beztsinna, Bottos, Craig, Dahl, Elmoslemany, Fry, Gadd, Gaudana, Grass, Kamaev, Kaur, Khutoryanskaya, Lam, Lamy, Lee, Li, Lidich, Lin, Llamas-Moreno, Meisner, Mishra, Morrison, Morrison, Morrison, Mun, Neva Kandzija, O'Brart, Palac, Pavelić, Pepić, Prausnitz, Rathore, Shen, Singh, Vanic, Vanic, Verma, Vitaliy V. Khutoryanskiy, Wagner, Wollensak, Yu   +44 more
core   +1 more source

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

BMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang, Muxin Yue, Kai Mao, Boon Chin Heng, Noor Azlin Yahya, Yunsong Liu, Zheng Li   +6 more
wiley   +1 more source

Femtosecond laser VisuMax application for corneal collagen crosslinking

Офтальмохирургия, 2020
Introduction. Corneal collagen crosslinking is a treatment method of advanced keratoconus, improving a «compaction» thickness or increasing a strength of corneal stroma.
I. V. Bogush, K. Y. Krasner, R. Sh. Sadrutdinov, K. B. Burilov, S. A. Karpeev, V. V. Chernykh   +5 more
doaj   +1 more source