Results 81 to 90 of about 186,523 (222)

Two-year topographic and densitometric outcomes of accelerated (45 mW/cm2) transepithelial corneal cross-linking for keratoconus: a case-control study

BMC Ophthalmology, 2018
Background Conventional corneal cross-linking is effective for retarding the progression of keratoconus. However the long-term efficacy and safety of accelerated (45 mW/cm2) transepithelial corneal cross-linking (ATE-CXL) on progressive keratoconus (KC ...
Jinrong Huang, Yang Shen, Weijun Jian, Haipeng Xu, Meiyan Li, Jing Zhao, Xingtao Zhou, Hongfei Liao   +7 more
doaj   +1 more source

Descemet stripping automated endothelial keratoplasty in Fuchs' corneal endothelial dystrophy: Anterior segment optical coherence tomography and in vivo confocal microscopy analysis [PDF]

, 2015
Background: To evaluate the in vivo corneal changes using in vivo confocal microscopy (IVCM) and anterior segment optical coherence tomography (AS-OCT) in patients with Fuchs' dystrophy who underwent Descemet stripping automated endothelial keratoplasty (
Busin, Massimo, Favuzza, Eleonora, Mencucci, Rita, Tartaro, Ruggero, Virgili, Gianni   +4 more
core   +1 more source

CORNEAL DENSITOMETRY EVALUATION IN DIFFERENT STAGES OF KERATOCONUS COMPARED TO NORMAL CORNEA

ALEXMED ePosters
Alaa Ghaith, Tamer Massoud, Shahira Mahmoud, Gamal Saber Mansour   +3 more
openalex   +3 more sources

Factors influencing haze formation and corneal flattening, and the impact of haze on visual acuity after conventional collagen cross-linking: a 12-month retrospective study

BMC Ophthalmology, 2021
Background Our aim was to determine associations of pachymetry, keratometry, and their changes with haze formation and corneal flattening after collagen cross-linking, and to analyse the relationship between postoperative haze and visual outcome. Methods
Anita Csorba, Kinga Kránitz, Péter Dormán, Andrea Popper-Sachetti, Huba Kiss, Irén Szalai, Zoltán Zsolt Nagy   +6 more
doaj   +1 more source

CRISPR/Cas9 DNA cleavage at SNP-derived PAM enables both in vitro and in vivo KRT12 mutation-specific targeting [PDF]

, 2015
CRISPR/Cas9-based therapeutics hold the possibility for permanent treatment of genetic disease. The potency and specificity of this system has been used to target dominantly inherited conditions caused by heterozygous missense mutations through inclusion
C B T Moore, C Smith, CA Schneider, D G Courtney, D M L Pedrioli, DG Courtney, DG Courtney, E H A Allen, E Maurizi, EHA Allen, ER Westra, FA Ran, G Schwank, H Liao, H Yin, J E Moore, K Yoshimi, KJ Livak, M A Nesbit, MW Pfaffl, O Shalem, PD Hsu, S D Atkinson, SD Atkinson, T Cao, T Wang, W H I McLean, WW Kao, Y Wu   +28 more
core   +2 more sources

Donor age and long-term culture do not negatively influence the stem potential of limbal fibroblast-like stem cells [PDF]

, 2016
In regenerative medicine the maintenance of stem cell properties is of crucial importance. Ageing is considered a cause of reduced stemness capability. The limbus is a stem niche of easy access and harbors two stem cell populations: epithelial stem cells
Arancio, W., Cillino, G., Cillino, S., Coppola, A., DI CARA, G., Giordano, C., Musso, R., Pitrone, M., Pizzolanti, G., Pucci Minafra, I., Tomasello, L.   +10 more
core   +3 more sources

Lifespan-increasing drug nordihydroguaiaretic acid inhibits p300 and activates autophagy. [PDF]

, 2019
Aging is characterized by the progressive loss of physiological function in all organisms. Remarkably, the aging process can be modulated by environmental modifications, including diet and small molecules.
Andersen, Julie, Butler, Victoria J, Chamoli, Manish, Jung, Manfred, Kao, Aimee W, Ng, Che-Ping, Simon, Roman P, Tezil, Tugsan, Verdin, Eric   +8 more
core   +1 more source

Optical quality of the cornea after Descemet membrane endothelial keratoplasty surgery: early results from Türkiye

Korean Journal of Transplantation, 2023
Background : Descemet membrane endothelial keratoplasty (DMEK) is increasingly favored in the treatment of endothelial dysfunction due to its benefits, which include swift visual rehabilitation and recovery, a relatively low rejection rate, and superior ...
Emine Esra Karaca, Feyza Dicle Işık, Özlem Evren Kemer   +2 more
doaj   +1 more source

Obtaining Of β-Lactoglobulin By Gel Filtration Of Cow Milk Whey [PDF]

, 2019
Milk whey proteins carry out a number of important biological functions and also they are precursors of many biologically active peptides (antihypertensive peptides, antagonists of opioid receptors, regulators of intestinal motility, immunomodulatory ...
Datsyshyn, K. (Kateryna), Storozh, L. (Liudmyla), Yukalo, V. (Volodymyr)   +2 more
core   +3 more sources

Loss of Corneal Nerves and Corneal Haze in Patients with Fuchs’ Endothelial Corneal Dystrophy with the Transcription Factor 4 Gene Trinucleotide Repeat Expansion

Ophthalmology Science, 2023
Objective: Seventy percent of Fuchs’ endothelial corneal dystrophy (FECD) cases are caused by an intronic trinucleotide repeat expansion in the transcription factor 4 gene (TCF4). The objective of this study was to characterize the corneal subbasal nerve
Matthew Gillings, MD, Andrew Mastro, MD, Xunzhi Zhang, Kelly Kiser, MD, Jane Gu, Chao Xing, PhD, Danielle M. Robertson, OD, PhD, W. Matthew Petroll, PhD, V. Vinod Mootha, MD   +8 more
doaj   +1 more source