Results 81 to 90 of about 136,951 (330)

Epidemiology and tumor microenvironment of ocular surface and orbital tumors on growth and malignant transformation

Frontiers in Oncology
The ocular surface and orbit constitute unique microenvironments in the human body. Current advances in molecular research have deepened our understanding of tumor development in these regions.
Shangkun Ou, Shangkun Ou, Shangkun Ou, Shangkun Ou, Shangkun Ou, Shangkun Ou, Yuan Lin, Yuan Lin, Yuan Lin, Yuan Lin, Yuan Lin, Yuan Lin, Yujie Zhang, Yujie Zhang, Yujie Zhang, Yujie Zhang, Yujie Zhang, Yujie Zhang, Ke Shi, Ke Shi, Ke Shi, Ke Shi, Ke Shi, Ke Shi, Huping Wu, Huping Wu, Huping Wu, Huping Wu, Huping Wu, Huping Wu   +29 more
doaj   +1 more source

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

Advanced Science, EarlyView.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang, Xiaoyu Zhou, Mengdan Li, Chao Zhang, Haiyan Xu, Jingyi He, Li Zhan, Yueling Gu, Hao Gu, Tianyu Tu, Hanfang Liu, Taotao Lu, Yueming Zheng, Jian Li, Zhaobing Gao, Yixiang Xu   +15 more
wiley   +1 more source

Greening vision: balancing clinical excellence and ecological sustainability in eye health

Frontiers in Public Health
The rapid advancement of ophthalmic medicine has significantly improved global visual health but concurrently imposed substantial ecological costs, creating an environmental paradox between efficient treatment and sustainability. This review explores the
Bin Lin, Bin Lin, Bin Lin, Bin Lin, Bin Lin, Bin Lin, Jing Tang, Wei Liang, Wei Liang, Wei Liang, Wei Liang, Wei Liang, Wei Liang, Peng Shi, Peng Shi, Peng Shi, Peng Shi, Peng Shi, Peng Shi, Dong-kan Li, Dong-kan Li, Dong-kan Li, Dong-kan Li, Dong-kan Li, Dong-kan Li   +24 more
doaj   +1 more source

Laser in situ keratomyleusis (LASIK) for correction of myopia and hypermetropia: Our one year experience [PDF]

Vojnosanitetski Pregled, 2009
Background/Aim. Laser in situ keratamileusis (LASIK) is the most commonly used refractive surgical method worldwide. The aim of this study was to examine the effectiveness and safety of LASIK in the correction of myopia and hyperopia. Methods.
Vukosavljević Miroslav, Milivojević Milorad, Resan Mirko, Cerović Vesna   +3 more
doaj   +1 more source

Inhibition of SLC11A1‐Mediated Lysosomal Iron Accumulation in Microglia Promotes Repair Following White Matter Stroke

Advanced Science, EarlyView.
Genetic and pharmacological inhibition of SLC11A1 functioning as an H+/Fe2+ antiporter–mediated lysosomal iron accumulation in microglia promotes lysosomal lumen acidification, increases CTSD expression, enhances lysosomal myelin debris uptake and degradation, and promotes repair following white matter stroke. ABSTRACT White matter stroke (WMS) results
Lingling Qiu, Yajie Zhang, Yushi Tang, Hongli Hu, Ying Zhang, Junwen Xue, Hao Wang, Yecheng Wang, Chunfeng Liu, Jia Jia, Jian Cheng, Yongjun Cao   +11 more
wiley   +1 more source

Visual outcomes and spectacle independence of a non-diffractive wavefront-shaping intraocular lens in post-LASIK patients

Frontiers in Medicine
PurposeTo compare visual outcomes, depth of field (DOF), spectacle independence, and patient satisfaction of cataract patients with and without previous myopic laser in situ keratomileusis (LASIK) surgery who received a non-diffractive extended range-of ...
Wei Fan, Wei Fan, Wei Fan, Wei Fan, Wei Fan, Wei Fan, Meiyi Zhu, Meiyi Zhu, Meiyi Zhu, Meiyi Zhu, Meiyi Zhu, Meiyi Zhu, Guangbin Zhang, Guangbin Zhang, Guangbin Zhang, Guangbin Zhang, Guangbin Zhang, Guangbin Zhang   +17 more
doaj   +1 more source

Use of topical tacrolimus in ophthalmology: Nonsystematic review

The Pan-American Journal of Ophthalmology, 2020
The two immunosuppressants most used topically in ophthalmology are cyclosporine (CS) and tacrolimus (TL). Their mechanism of action is similar, but the TL is ten to a hundred times more powerful than the CS.
Morgana Arima Vedovato, Thaynara Queiroz Mendes Do Carmo, Livia Cristina Rios, Vinicius Cidral Corrêa, Fernanda Ribeiro Oliveira, Nelson Chamma Capelanes, Bernardo Kaplan Moscovici   +6 more
doaj   +1 more source

Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy

Advanced Science, EarlyView.
Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro, Yoojin Chang, Jeeyoon Kim, Seungjae Lee, Sangyun Na, Cheolhong Park, Hyunhyub Ko   +6 more
wiley   +1 more source

Intravitreal drug injection for glaucoma: mechanisms, clinical efficacy, and future horizons

Frontiers in Pharmacology
Intravitreal drug injection has emerged as a transformative approach in glaucoma management, overcoming the limitations of traditional treatments such as poor compliance with topical medications and high complication rates of filtration surgery.
Bin Lin, Bin Lin, Bin Lin, Bin Lin, Bin Lin, Bin Lin, Peng Shi, Peng Shi, Peng Shi, Peng Shi, Peng Shi, Peng Shi, Dong-Kan Li, Dong-Kan Li, Dong-Kan Li, Dong-Kan Li, Dong-Kan Li, Dong-Kan Li   +17 more
doaj   +1 more source

Bioinspired Tissue Transparency: Achieving Sclera‐to‐Cornea Transplantation

Advanced Science, EarlyView.
A bioinspired decellularization‐compression‐locking tactic (DCLT) is developed to transform human sclerae into transparent corneal substitutes. These clear, robust, and pro‐regenerative substitutes are capable of repairing complex corneal injuries, including chemical burns, keratoconus, and penetrating wounds, demonstrating their clinical potential to ...
Xiuli Sun, Long Zhao, Zhen Shi, Jingting Wang, Shang Yang, Xia Qi, Hengrui Zhang, Ting Wang, Weiyun Shi   +8 more
wiley   +1 more source