Results 81 to 90 of about 25,735 (191)

SLC4A11 depletion impairs NRF2 mediated antioxidant signaling and increases reactive oxygen species in human corneal endothelial cells during oxidative stress

Scientific Reports, 2017
Corneal endothelial dystrophy is a progressive disease with gradual loss of vision and characterized by degeneration and dysfunction of corneal endothelial cells.
Sanjukta Guha, Sunita Chaurasia, Charanya Ramachandran, Sanhita Roy   +3 more
doaj   +1 more source

Outcomes of therapeutic penetrating keratoplasty and deep anterior lamellar keratoplasty in acanthamoeba keratitis: A systematic review and meta‐analysis

Acta Ophthalmologica, EarlyView.
Abstract While acanthamoeba keratitis (AK) is a sight‐threatening corneal infection, a thorough comparison of the outcomes of therapeutic penetrating keratoplasty (PK) and therapeutic deep anterior lamellar keratoplasty (DALK) is lacking. We aimed to compare clinical outcomes of PK and DALK in AK.
Gábor Tóth, Junbo Wang, Shanhe Liu, Shuailin Li, Szilárd Váncsa, Mátyás Paczkó, Tamás Kói, Péter Hegyi, Nóra Szentmáry   +8 more
wiley   +1 more source

Endothelial Cell Loss after Phacoemulsification according to Different Anterior Chamber Depths

Journal of Ophthalmology, 2015
Purpose. To compare the loss of corneal endothelial cells after phacoemulsification according to different anterior chamber depths (ACDs). Methods. We conducted a prospective study on 135 eyes with senile cataracts.
Hyung Bin Hwang, Byul Lyu, Hye Bin Yim, Na Young Lee   +3 more
doaj   +1 more source

Peripheral targets for neuropathic pain

British Journal of Pharmacology, EarlyView.
Neuropathic pain represents a significant clinical challenge, with still limited pharmacological approaches to symptomatic relief. This review focuses on molecular targets implicated in neuropathic pain, particularly those involved in peripheral mechanisms. Using the IUPHAR/BPS database of biological targets, their occurrence together with ‘neuropathic
Amirhossein Afsharipour, Cosmin I. Ciotu, Felix J. Resch, Michael J. M. Fischer   +3 more
wiley   +1 more source

Premium Intraocular Lens Selection in Patients With Glaucoma: A Clinical Review

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Glaucoma frequently coexists with cataract, but glaucomatous functional loss, ocular‐surface disease, anatomical abnormalities, and treatment‐related refractive variability may reduce tolerance of premium intraocular lenses. This narrative review critically appraises evidence relevant to lens selection in glaucoma. Central visual‐field status,
Zhihao Liu, Yajuan Zheng, Mingxuan Wang, Jing Zhao   +3 more
wiley   +1 more source

Thirty Years of Autologous Platelet Concentrates: From Platelet‐Rich Plasma to Platelet‐Rich Fibrin

Journal of Periodontal Research, EarlyView.
This review highlights the 30 years of evolution of APCs, with a focus on their clinical applications and recent technological advancements. ABSTRACT Nearly three decades have now passed since autologous platelet concentrates (APCs) were introduced into clinical practice.
Richard J. Miron, Nathan E. Estrin, Paras Ahmad, Nima Farshidfar, Masako Fujioka‐Kobayashi, Yufeng Zhang, Mario Romandini, Reinhard Gruber   +7 more
wiley   +1 more source

The Role of Viruses in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the presence and potential pathogenic role of viruses in periodontitis. Design: Narrative Review; Population: Patients with periodontitis; Exposure: Detection of viruses in oral samples (biopsies, saliva, gingival crevicular fluid, subgingival plaque, blood); Outcome: Viral prevalence, load ...
Kim Natalie Stolte, Jørgen Slots, Henrik Dommisch   +2 more
wiley   +1 more source

Retrospective evaluation of outcomes in dogs with non‐associative immune‐mediated haemolytic anaemia treated with rivaroxaban as a sole or adjunctive thromboprophylaxis agent: 34 cases (2018‐2024)

Journal of Small Animal Practice, EarlyView.
Objectives To describe clinical outcomes, thromboembolic and haemorrhagic complications, and treatment characteristics in dogs with non‐associative immune‐mediated haemolytic anaemia treated with rivaroxaban at a UK referral hospital. Materials and Methods Retrospective descriptive study of dogs diagnosed with non‐associative immune‐mediated haemolytic
S. Conway, L. Jenkins, J. Reeve
wiley   +1 more source

Clinicogenetic Characterization of H Syndrome in a South African Child

Pediatric Dermatology, EarlyView.
ABSTRACT H syndrome is a rare autosomal recessive genodermatosis caused by loss‐of‐function SLC29A3 variants, combining hyperpigmented indurated plaques and hypertrichosis with life‐threatening autoinflammation. We report a 5‐year‐old South African girl of first‐cousin parents who presented with hyperinflammation mimicking macrophage activation ...
Tshimogo Tswelopele Sathekge, Claude Bailly   +1 more
wiley   +1 more source

Interventional human ocular safety experiments for 222‐nm far‐ultraviolet‐C lamp irradiation

Photochemistry and Photobiology, Volume 101, Issue 2, Page 517-526, March/April 2025.
To directly assess the ocular safety of 222‐nm far‐ultraviolet‐C (UVC) irradiation in humans, five subjects were exposed to 222‐nm UVC at doses of 22, 50, and 75 mJ/cm2. The findings indicate that far‐UVC irradiation does not cause “clinically significant photokeratitis” or long‐term ocular damage, though it may induce temporary discomfort.
Kazunobu Sugihara, Sachiko Kaidzu, Masahiro Sasaki, Masaki Tanito   +3 more
wiley   +1 more source