Results 61 to 70 of about 25,735 (191)

Regenerative capacity of the corneal transition zone for endothelial cell therapy

Stem Cell Research & Therapy, 2020
The corneal endothelium located on the posterior corneal surface is responsible for regulating stromal hydration. This is contributed by a monolayer of corneal endothelial cells (CECs), which are metabolically active in a continuous fluid-coupled efflux ...
Nicole Ming Sie, Gary Hin-Fai Yam, Yu Qiang Soh, Matthew Lovatt, Deepinder Dhaliwal, Viridiana Kocaba, Jodhbir S. Mehta   +6 more
doaj   +1 more source

The Multiple Criteria Qualitative Value‐Based Pricing Framework “MARIE” for Novel Cell and Gene Therapy

Clinical Pharmacology &Therapeutics, EarlyView.
When setting the price of cell and gene therapies in Japan, the factors considered include the manufacturing and operating costs of the new drug or a comparator, leading to discrepancies between price and values, in particular those specific to cell and gene therapies.
Akina Takami, Ataru Igarashi
wiley   +1 more source

Artificial Intelligence in Ophthalmology: From Methodological Advances to Clinical Translation and Future Directions

Eye &ENT Research, EarlyView.
ABSTRACT Artificial intelligence (AI) is reshaping ophthalmology from task‐specific image analysis toward multimodal, longitudinal, and clinically integrated decision support. This narrative review summarizes the methodological evolution of ophthalmic AI, including traditional machine learning, task‐specific deep learning, self‐supervised learning ...
Yuxin Liu, Hanruo Liu
wiley   +1 more source

Observations of the efficacy of the artificial lens cushion plate technique in hard-core cataract surgery

Frontiers in Medicine
ObjectiveTo evaluate the efficacy of intraocular lens (IOL) cushion plate technology in reducing corneal endothelial cell loss during hard-core cataract surgery compared with conventional ultrasonic emulsification.MethodsSeventy-six patients with hard ...
ZhiQing Huang, MiYun Zheng, MaoDong Xu, Lei Cai, XiaoQing Song   +4 more
doaj   +1 more source

Nanophotonic Biosensors and the Paradigm of Trans‐Scale Autonomous Bio‐Integrated Diagnostics for Addressing Health Complexities

Electron, EarlyView.
Physics‐driven advances in optical nanobiosensors for rapid, miniaturized, and point‐of‐care diagnostics for next‐generation decentralized and personalized healthcare based on sensor intelligence. ABSTRACT Public health emergencies and the escalating burden of chronic diseases necessitate a paradigm shift from centralized laboratory testing to rapid ...
Vishal Chaudhary, Harsh Sable, Sonu Sonu, Lakshita Phor, Reddicherla Umapathi, Pradeep Bhadola   +5 more
wiley   +1 more source

A Meta-Analysis Comparing Postoperative Complications and Outcomes of Femtosecond Laser-Assisted Cataract Surgery versus Conventional Phacoemulsification for Cataract

Journal of Ophthalmology, 2017
Objective. This meta-analysis aimed to compare the outcomes and postoperative complications between femtosecond laser-assisted cataract surgery (FLACS) and conventional phacoemulsification cataract surgery (CPCS). Methods.
Zi Ye, Zhaohui Li, Shouzhi He
doaj   +1 more source

Risk factors for endothelial cell loss after corneal transplantation

Acta Ophthalmologica, 2012
AbstractPurpose To analyze risk factors for endothelial cell loss after corneal transplantation.Methods Cohort study including 1438 consecutive eyes of 1438 patients who underwent Penetrating Keratoplasty, Anterior Lamellar Keratoplasty, or Descemet Stripping with Endothelial Keratoplasty between 1992 and 2010.
V BORDERIE, J BULLET, O TOUZEAU, E BASLI, L LAROCHE   +4 more
openaire   +1 more source

Protective effects of adiponectin receptor agonists against equine lamellar endoplasmic reticulum stress

Equine Veterinary Journal, EarlyView.
Abstract Background Lamellar endoplasmic reticulum (ER) stress occurs in hyperinsulinemia‐associated and sepsis‐related laminitis. Adiponectin is associated with reduced laminitis risk and inhibits ER stress in other species. Objectives To induce ER stress in ex vivo equine lamellar cells using pharmacological agents.
Marine A. Barnabé, Jonathan Elliott, Nicola J. Menzies‐Gow, Simon R. Bailey, Nicholas J. Bamford, Yu‐Mei Chang, Matthew C. Gage   +6 more
wiley   +1 more source

Effects of two ophthalmic viscoelastic devices on the corneal endothelium after phacoemulsification

Philippine Journal of Ophthalmology, 2008
Objective: This study compared the effects of Discovisc (DV) and Amvisc Plus (AP) on the corneal endothelium of patients after phacoemulsification cataract surgery.
Michelle Doronila Lingao, MD, Harvey Siy Uy,MD   +1 more
doaj  

Corneal endothelium after deep anterior lamellar keratoplasty and penetrating keratoplasty for keratoconus: A four-year comparative study

Indian Journal of Ophthalmology, 2012
Purpose: To compare the status of corneal endothelium and central corneal thickness within the first four postoperative years after deep anterior lamellar keratoplasty (DALK) and penetrating keratoplasty (PK) in patients with keratoconus.
Anil Kubaloglu, Arif Koytak, Esin Sogutlu Sari, Sibel Akyol, Ekrem Kurnaz, Yusuf Ozerturk   +5 more
doaj   +1 more source