Results 101 to 110 of about 4,940,025 (211)

Plant‐derived nanovesicles as potential drug delivery systems for topical use: Emerging applications in dermatology and cosmetology

VIEW, EarlyView.
Plant‐derived nanovesicles (PDNVs) are naturally secreted by fruit, vegetables, seeds, leaves and other natural sources. Used as drug delivery systems, they can combine intrinsic therapeutic activity, enhanced skin permeation and cargo‐carrying capacity, suitable for dermatological and cosmetic applications including hydration, antioxidant/anti ...
Dorotea Fiore, Beatrice Pellegrini, Antonia Mancuso, Maria Chiara Cristiano, Salvatore Panza, Donatella Paolino   +5 more
wiley   +1 more source

An Optimized Mechanical Peeling Protocol for Mouse Corneal Endothelium

Bioengineering
Corneal endothelium is a single layer of polygonal cells responsible for maintaining stromal dehydration and corneal transparency. Isolating corneal endothelium from murine models is exceptionally challenging without an established protocol, which ...
Zhenwei Song, Liujiang Song, Hua Mei
doaj   +1 more source

The protective effect of simvastatin against ultraviolet B-induced corneal endothelial cell death

Indian Journal of Ophthalmology, 2018
Purpose: Excessive ultraviolet B (UVB) exposure causing corneal endothelium injury, including apoptosis, is a serious condition. Therefore, drugs that can inhibit apoptosis in corneal endothelial cells represent an effective strategy.
Yi-Ru Ho, Chih-Hung Lin, Chan-Yen Kuo
doaj   +1 more source

Assessing a Model for a Complex Systemic Disorder—The Value of Male Mice With a Supernumerary X Chromosome for Klinefelter Syndrome Research

Andrology, EarlyView.
ABSTRACT Introduction Direct experimental investigation of Klinefelter syndrome (KS) in patients is limited because the syndrome manifests heterogeneously and affects multiple organ systems. Studying KS therefore requires a model that captures this complexity as accurately as possible while still permitting controlled experimental manipulation ...
Fariba Saadati, Joachim Wistuba
wiley   +1 more source

Changes in the morphology of corneal endothelial cells in young myopic adults after 6 months of wearing soft contact lenses: a Malaysian perspective

, 2018
Asmah Ahmad, Bariah Mohd-Ali, Bashirah Ishak Optometry and Vision Science Program and Centre for Community Health, Faculty of Health Science, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia Purpose: Soft contact lens wear is most frequently ...
Ahmad A, Ishak B, Mohd-Ali B
core  

Genetic risk factors in Finnish patients with Fuchs endothelial corneal dystrophy

Acta Ophthalmologica, EarlyView.
Abstract Purpose To study the genetic risk factors of Fuchs endothelial corneal dystrophy (FECD) in the Finnish population using hospital‐based and large biobank cohorts. Methods We genotyped a cohort of 107 Finnish patients with FECD for the primary associated genetic risk factor, the TCF4 (CTG)>50 expansion, and studied their clinical phenotype.
Inka‐Tuulevi Vähämäki, Annamari T. Immonen, Joel T. Rämö, Aino M. Jaakkola, Kari Krootila, Maria Kaukonen, FinnGen, Aarno Palotie, Hannes Lohi, Tero T. Kivelä, Joni A. Turunen   +10 more
wiley   +1 more source

Morphological Changes of Human Corneal Endothelial Cells after Rho-Associated Kinase Inhibitor Eye Drop (Ripasudil) Administration: A Prospective Open-Label Clinical Study.

PLoS ONE, 2015
PurposeTo investigate the effect and safety of a selective Rho kinase inhibitor, ripasudil 0.4% eye drops, on corneal endothelial cells of healthy subjects.DesignProspective, interventional case series.MethodsIn this study, 6 healthy subjects were ...
Hiroko Nakagawa, Noriko Koizumi, Naoki Okumura, Hideki Suganami, Shigeru Kinoshita   +4 more
doaj   +1 more source

Human corneal endothelial cell growth on a silk fibroin membrane

, 2011
Tissue engineering of the cornea could overcome shortages of donor corneas for transplantation and improve quality. Our aim was to grow an endothelial layer on a substratum suitable for transplant.
Talia Giovenco, Harkin, Damien G., Harkin, Damien, Giovenco, Talia, Peter W. Madden, Jonathan N.X. Lai, Traian V. Chirila, Karina A. George, Lai, Jonathan N. X., Chirila, Traian, Damien G. Harkin, Chirila, Traian V., George, Karina, Madden, Peter, Madden, Peter W., Lai, Jonathan, George, Karina A.   +16 more
core   +1 more source

Can mesenchymal stromal cells differentiate into corneal cells? A systematic review of published data [PDF]

, 2015
The majority of stem cell therapies for corneal repair are based upon the use of progenitor cells isolated from corneal tissue, but a growing body of literature suggests a role for mesenchymal stromal cells (MSC) isolated from non-corneal tissues.
Cronin, Brendan G., Harkin, Damien G., Sutherland, Allison J., Li, Fiona J., Foyn, Leanne, Bray, Laura J.   +5 more
core   +1 more source

Corneal transplantation: Restoring sight to the blind

Acta Ophthalmologica, EarlyView.
Abstract Corneal blindness is one of the leading causes of vision loss worldwide. Transplantation of the cornea can restore vision and make blind patients see again. Corneal transplant surgery has undergone major evolution in recent decades with the advent of minimally invasive lamellar surgical approaches such as DMEK and DALK.
Claus Cursiefen
wiley   +1 more source