Results 81 to 90 of about 4,940,025 (211)

Arginine depletion as a mechanism for the immune privilege of corneal allografts. [PDF]

, 2011
The cornea is an immune privileged tissue. Since arginase has been found to modulate T-cell function by depleting arginine, we investigated the expression of arginase in the cornea and its possible role in immune privilege using a murine transplant model.
Larkin, Daniel FP, George, Andrew J.T., Fu, Hongmei, Coe, D, Hongmei Fu, Chai, J-G, Zaher, S, David Coe, George, Andrew JT, Fu, H, Khan, A, Larkin, Daniel F.P., Jian-Guo Chai, Ingrid Müller, Kropf, P, Müller, Ingrid, Kropf, Pascale, Larkin, DFP, George, AJT, Adnan Khan, Khan, Adnan, Zaher, Sarah, Daniel F. P. Larkin, Mueller, I, Pascale Kropf, Coe, David, Sarah Zaher, Andrew J. T. George, Chai, Jian-Guo   +28 more
core   +1 more source

Image_1_Extracellular Vesicles Derived From Human Corneal Endothelial Cells Inhibit Proliferation of Human Corneal Endothelial Cells.TIF

, 2022
Corneal endothelial cells (CEnCs) are a monolayer of hexagonal cells that are responsible for maintaining the function and transparency of the cornea. Damage or dysfunction of CEnCs could lead to blindness.
Mohit Parekh (6643547), Sajjad Ahmad (768814), Hefin Rhys (9551069), Tiago Ramos (817043), Stefano Ferrari (224700)   +4 more
core   +1 more source

Artificial Intelligence in Ophthalmology: From Methodological Advances to Clinical Translation and Future Directions

Eye &ENT Research, EarlyView.
ABSTRACT Artificial intelligence (AI) is reshaping ophthalmology from task‐specific image analysis toward multimodal, longitudinal, and clinically integrated decision support. This narrative review summarizes the methodological evolution of ophthalmic AI, including traditional machine learning, task‐specific deep learning, self‐supervised learning ...
Yuxin Liu, Hanruo Liu
wiley   +1 more source

Descemet’s Membrane Supports Corneal Endothelial Cell Regeneration in Rabbits

Scientific Reports, 2017
Descemet’s membrane (DM) helps maintain phenotype and function of corneal endothelial cells under physiological conditions, while little is known about the function of DM in corneal endothelial wound healing process. In the current study, we performed in
Jingyao Chen, Zhiyuan Li, Liying Zhang, Shangkun Ou, Yanzi Wang, Xin He, Dulei Zou, Changkai Jia, Qianqian Hu, Shu Yang, Xian Li, Juan Li, Junqi Wang, Huimin Sun, Yongxiong Chen, Ying-Ting Zhu, Scheffer C. G. Tseng, Zuguo Liu, Wei Li   +18 more
doaj   +1 more source

Evaluation of interface quality in organ-cultured lamellar corneal transplants [PDF]

, 2012
Background: With increasing numbers of lamellar keratoplasties, eye banks are challenged to deliver precut lamellar donor tissue. In Europe, the most common technique of corneal storage is organ culture which requires a deswelling process before surgical
Kohnen, Thomas, Wolf, Armin, Kook, Daniel, Grüterich, Martin, Jagow, Burkhard von, Kampik, Anselm, Lackerbauer, Carlo A., Messmer, Elisabeth M.   +7 more
core   +1 more source

Nanophotonic Biosensors and the Paradigm of Trans‐Scale Autonomous Bio‐Integrated Diagnostics for Addressing Health Complexities

Electron, EarlyView.
Physics‐driven advances in optical nanobiosensors for rapid, miniaturized, and point‐of‐care diagnostics for next‐generation decentralized and personalized healthcare based on sensor intelligence. ABSTRACT Public health emergencies and the escalating burden of chronic diseases necessitate a paradigm shift from centralized laboratory testing to rapid ...
Vishal Chaudhary, Harsh Sable, Sonu Sonu, Lakshita Phor, Reddicherla Umapathi, Pradeep Bhadola   +5 more
wiley   +1 more source

Research progress on the impact of cataract surgery on corneal endothelial cells

Advances in Ophthalmology Practice and Research
Background: Cataracts are a common eye disease and a major cause of blindness in China and worldwide. In China, the incidence of cataracts among people over 60 years old is as high as 80%.
Chen Yang, Qi An, Han Zhou, Hongyan Ge
doaj   +1 more source

Therapy of corneal endothelial dysfunction with corneal endothelial cell-like cells derived from skin-derived precursors

, 2017
Corneal endothelial dysfunction occurs when corneal endothelial cells (CECs) are dramatically lost and eventually results in vision loss. Corneal transplantation is the only solution at present.
Xinyi Wu, Le Yang, Peng Sun, Liqun Du, Lin Shen, Canwei Zhang   +5 more
core   +1 more source

Video_1_Extracellular Vesicles Derived From Human Corneal Endothelial Cells Inhibit Proliferation of Human Corneal Endothelial Cells.MP4

, 2022
Corneal endothelial cells (CEnCs) are a monolayer of hexagonal cells that are responsible for maintaining the function and transparency of the cornea. Damage or dysfunction of CEnCs could lead to blindness.
Mohit Parekh (6643547), Sajjad Ahmad (768814), Hefin Rhys (9551069), Tiago Ramos (817043), Stefano Ferrari (224700)   +4 more
core   +1 more source

Protective effects of adiponectin receptor agonists against equine lamellar endoplasmic reticulum stress

Equine Veterinary Journal, EarlyView.
Abstract Background Lamellar endoplasmic reticulum (ER) stress occurs in hyperinsulinemia‐associated and sepsis‐related laminitis. Adiponectin is associated with reduced laminitis risk and inhibits ER stress in other species. Objectives To induce ER stress in ex vivo equine lamellar cells using pharmacological agents.
Marine A. Barnabé, Jonathan Elliott, Nicola J. Menzies‐Gow, Simon R. Bailey, Nicholas J. Bamford, Yu‐Mei Chang, Matthew C. Gage   +6 more
wiley   +1 more source