Results 161 to 170 of about 4,940,025 (211)

Corneal Xenotransplantation: Lessons From Allograft Immunobiology and Emerging Translational Strategies

Xenotransplantation, Volume 33, Issue 6, November/December 2026.
ABSTRACT Corneal transplantation is an effective sight‐restoring procedure, yet its global impact remains constrained by limited and uneven access to human donor tissue and by immune‐mediated graft failure, particularly in high‐risk recipients. Xenotransplantation offers a potentially scalable alternative, but successful clinical translation requires ...
Ansu A. John, Ellen H. Koo
wiley   +1 more source

Endothelial Exostosin‐1 Is Needed for Glycocalyx Integrity and Inflammatory Resolution in Acute Lung Injury

The FASEB Journal, Volume 40, Issue 19, 15 October 2026.
Endothelial Ext1 is essential for maintaining heparan sulfate–rich endothelial glycocalyx integrity. Loss of Ext1 reduces glycocalyx thickness, resulting in enhanced leukocyte adhesion, increased vascular permeability, and exaggerated inflammatory responses following lipopolysaccharide (LPS) challenge.
Yuki Kawasaki, Hiroyuki Tomita, Kodai Suzuki, Chihiro Takada, Hirotaka Asano, Soichiro Kano, Yugo Wakayama, Hirotsugu Fukuda, Toru Minamiyama, Genki Yoshimura, Ryo Kamidani, Yoshinori Kakino, Tomotaka Miura, Yuichiro Kitagawa, Tetsuya Fukuta, Takahito Miyake, Akio Suzuki, Kazu Matsumoto, Nobuyuki Tetsuka, Shozo Yoshida, Yoichi Maekawa, Yu Yamaguchi, Hideshi Okada   +22 more
wiley   +1 more source

Endothelial Cell Therapy for Postkeratoplasty Corneal Endothelial Failure

Ophthalmology
Yuto Kataoka, Morio Ueno, Takefumi Yamaguchi, Yasufumi Tomioka, Koichi Wakimasu, Mariko Shirane, Koji Kitazawa, Hideki Fukuoka, Tsutomu Inatomi, Chie Sotozono, Shigeru Kinoshita   +10 more
openaire   +2 more sources

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Cell therapy in corneal endothelial disease

Current Opinion in Ophthalmology, 2022
Purpose of review Endothelial keratoplasty is the current gold standard for treating corneal endothelial diseases, achieving excellent visual outcomes and rapid rehabilitation. There are, however, severe limitations to donor tissue supply and uneven access to surgical teams and facilities across the globe.
Evan N, Wong, Jodhbir S, Mehta
openaire   +2 more sources

The corneal endothelial cell interface

Acta Ophthalmologica, 1985
Abstract. The apical edges of corneal endothelial cells have been separated along lines forming a crisscross pattern, by the help of a special method of preparation. The visualization by SEM of the lateral faces of the cells is thereby made possible.
M, Davanger, E G, Olsen
openaire   +2 more sources

iPSC-Derived Corneal Endothelial Cells

2023
The corneal endothelium is the innermost monolayer of the cornea that maintains corneal transparency and thickness. However, adult human corneal endothelial cells (CECs) possess limited proliferative capacity, and injuries can only be repaired by migration and enlargement of resident cells.
Qingjun, Zhou, Zongyi, Li, Haoyun, Duan
openaire   +2 more sources

Receptors for Hyaluronan on Corneal Endothelial Cells

Experimental Eye Research, 1994
Previous investigations suggest that the corneal endothelium has specific binding sites for hyaluronan (HYA). In the present study, biochemical and immunological techniques were used to characterize these binding sites and to compare them with the liver endothelial cell (LEC) HYA receptor.
N, Forsberg, A, Von Malmborg, K, Madsen, W, Rolfsen, S, Gustafson   +4 more
openaire   +2 more sources

Corneal Endothelial Cell Density in Glaucoma

Cornea, 1997
We studied corneal endothelial cell density in patients with glaucoma.One hundred two patients with glaucoma were compared with 52 patients without glaucoma of the same age group. Exclusion criteria included history of either corneal disease, ocular inflammation, trauma, or surgery other than peripheral iridectomy.
M M, Gagnon, H M, Boisjoly, I, Brunette, M, Charest, M, Amyot   +4 more
openaire   +2 more sources

Corneal Endothelial Cell Measurements in Megalocornea

Archives of Ophthalmology, 1983
A pedigree of megalocornea manifested many of the characteristic features as well as some less common features of the disorder. Endothelial specular microscopy of affected patients disclosed normal endothelial cell densities and morphologic characteristics and increased total endothelial cell populations, suggesting a process of total corneal ...
G L, Skuta, J, Sugar, E S, Ericson
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Corneal Stromal and Endothelial Cell Precursors

Cornea, 2006
To isolate precursors of human corneal stromal and endothelial cells in vitro and to compare the distribution of rabbit corneal endothelial cell precursors in the central and peripheral regions of the cornea.Sphere-forming cells were isolated from human corneal stromal and endothelial cells by a reaggregation-free neurosphere assay.
Shiro, Amano, Satoru, Yamagami, Tatsuya, Mimura, Saiko, Uchida, Seiichi, Yokoo   +4 more
openaire   +2 more sources