Results 151 to 160 of about 4,940,025 (211)

Lipid–Polymeric Nanoencapsulation of Standardized Camellia sinensis Extract Enhances Antiangiogenic Activity and Ocular Biocompatibility

Chemistry &Biodiversity, Volume 23, Issue 11, November 2026.
Workflow for the synthesis, characterization, and biological evaluation of lipid–polymeric nanoparticles loaded with a chemically standardized Camellia sinensis extract, showing improved colloidal stability, ocular biocompatibility, and antiangiogenic activity. Created by the authors using BioRender.com.
Sarah Kelly Fernandes, Anízio Bastos de Souza, Líbia Andressa Leandro de Paula, Alessandra Cristine de Souza Matavel, Marcos Paulo Gomes Mol, Mariana de Oliveira Almeida, Vanessa Heloísa Ferreira de Faria, Carolina Paula de Souza Moreira   +7 more
wiley   +1 more source

Simvastatin Modulates Astrocyte and Microglial Reactivity and Aggressive Behavior After Chronic Sleep Deprivation in Rats

Journal of Neuroscience Research, Volume 104, Issue 11, November 2026.
Simvastatin modulates chronic sleep deprivation‐induced glial remodeling and behavioral responses. ABSTRACT Chronic sleep deprivation (SD) disrupts central nervous system homeostasis, promoting behavioral alterations and glial remodeling within limbic structures.
Higor Hernany Dias, Kevin Silva Müller, Gabriela Larissa Lima‐da‐Silva, Stephane da Silva Alves, Tatiane de Camargo Martins, Pedro Tadao Hamamoto Filho, José de Anchieta de Castro e Horta‐Júnior   +6 more
wiley   +1 more source

Adipose‐Derived Mesenchymal Stem Cells: Isolation, Origin, Phenotype Applications, and Challenges

MedComm, Volume 7, Issue 11, November 2026.
Bridging basic biology to clinical translation, this review systematically explores the in vivo origins and evolving isolation techniques of AD‐MSCs. We dissect their diverse phenotype applications orchestrated by immunometabolic reprogramming, mitochondrial transfer, and extracellular vesicles.
Ziyang Liu, Guangming Tu, Chao Wang, Hongyan Zhao, Ziyi Wu, Wei Li, Li Chen, Bailin Niu   +7 more
wiley   +1 more source

In vitro model for Fuchs Endothelial Dystrophy and its effects on corneal endothelial cells

, 2020
Fuchs endothelial dystrophy (FED), a corneal endothelium disease, is one of the leading causes for corneal transplantation. During disease progression, Descemet membrane’s (DM), the corneal endothelial basement membrane, biomechanical properties such as ...
Jain, Deepak
core  

Neutrophils: Heterogeneity, Biology, Diseases, and Therapeutic Strategies

MedComm, Volume 7, Issue 11, November 2026.
Neutrophils exhibit remarkable functional plasticity and play dual roles in tissue protection and disease progression. This review summarizes their key biological functions and highlights the shift from conventional broad‐spectrum interventions to neutrophil‐based drug delivery systems.
Yibing Zhang, Siwen Wu, Yusi Wang, Die Hu, Li Yang   +4 more
wiley   +1 more source

145 Appendix Specific Deletion of Ephrin-B2 in Peripheral Endothelial Cells, but not in Heart Endocardial Cells Reveals an Essential Role of Ephrin-B2 in Peripheral

, 2014
Ephrin-B2 conventional knockout and endothelial specific knockout mice show the same angiogenesis defects in head, trunk and yolk sac as well as the same heart defects during embryonic development (Gerety and Anderson, 2002; Wang et al., 1998); ephrin-B2
Endothelial Cells
core  

High Doses of N‐Acetyl‐P‐Aminophenol Cause Acute Changes in Electroencephalographic and Electrocardiographic Activities in Wistar Rats

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 5, November 2026.
ABSTRACT N‐acetyl‐p‐aminophenol (APAP), or acetaminophen, is the most prescribed analgesic and antipyretic, even used in association with other drugs. Because it is easily bought in drugstores, much evidence about its toxic effects is known due to high doses or continuous use, which can lead to death in cases of intoxication.
Alex Luiz Menezes da Silva, Luiz Gustavo dos Reis de Freitas, Akira Otake Hamoy, Clarissa Araujo da Paz, Luan Oliveira Ferreira, Esther Padilha da Silveira, Maria Klara Otake Hamoy, Nilton Akio Muto, Dielly Catrina Favacho Lopes, Moisés Hamoy   +9 more
wiley   +1 more source

Ocular Manifestations of Metabolic Syndrome: A Systemic Vascular Phenotype

Diabetes, Obesity and Metabolism, Volume 28, Issue 11, Page 9809-9818, November 2026.
ABSTRACT Context Metabolic syndrome (MetS) is defined by central obesity, insulin resistance, hypertension and dyslipidemia. MetS affects over one‐third of US adults. Beyond its cardiovascular burden, MetS has clinically relevant associations with ocular health and may contribute to a systemic vascular and neuro‐metabolic phenotype involving the retina,
Ron T. Varghese, Ansu A. John
wiley   +1 more source

Cargo Stability of Extracellular Vesicles Derived From Non‐Diseased Sources: Effects of Storage and Handling Conditions

Journal of Cellular and Molecular Medicine, Volume 30, Issue 21, November 2026.
ABSTRACT Extracellular vesicles (EVs) are nanoscale, membrane‐enclosed particles that transfer proteins, nucleic acids, lipids, and other bioactive molecules between cells. Their cargo‐bearing capacity supports applications in drug delivery, regenerative medicine, and biomarker development, but ex vivo handling can alter vesicle recovery and cargo ...
Khadijeh Abbasi, Mina Mohammadinasr, Roza Motavalli, Narges Arianfar, Attabak Toofani‐Milani, Moein Shirzad, Vahid Hosseini, Masoud Darabi   +7 more
wiley   +1 more source

Ocular Manifestations of Infectious Salmon Anaemia Virus Infection in Atlantic Salmon (Salmo salar)

Journal of Fish Diseases, Volume 49, Issue 11, November 2026.
ABSTRACT Eyes are essential sensory organs needed by teleost Atlantic salmon for high visual acuity and survival in both the wild and in aquaculture settings. In this work, we assessed the ocular manifestations of Infectious Salmon Anaemia Virus (ISAV) infection in Atlantic salmon by a cohabitation‐mediated infection assay and histological and ...
Emily Mahon, Rebecca R. Kwabiah, Hélène Paradis, Manuel A. Soto‐Dávila, Sathees Duglas, Raja Ram Gurung, Thurka Paramanathan, Ignacio Vasquez, Shams Al‐Badoosh, John Law, Javier Santander, Mark D. Fast, Robert L. Gendron   +12 more
wiley   +1 more source