Extracellular Vesicles Derived From Human Corneal Endothelial Cells Inhibit Proliferation of Human Corneal Endothelial Cells [PDF]
Frontiers in Medicine, 2022 Corneal endothelial cells (CEnCs) are a monolayer of hexagonal cells that are responsible for maintaining the function and transparency of the cornea. Damage or dysfunction of CEnCs could lead to blindness.
Rhys, Hefin +4 more
core +9 more sources
Regulation of Oxidative Stress in Corneal Endothelial Cells by Prdx6
Antioxidants, 2018 The inner layer of the cornea, the corneal endothelium, is post-mitotic and unable to regenerate if damaged. The corneal endothelium is one of the most transplanted tissues in the body.
Matthew Lovatt +3 more
doaj +2 more sources
Normal corneal endothelial cell density in Nigerians
Clinical Ophthalmology, 2016 Temitope Ewete,1 Efeoghene Uchenna Ani,2 Adegboyega Sunday Alabi1 1MeCure Eye Center, Lagos, 2Department of Ophthalmology, University of Port Harcourt, Port Harcourt, Nigeria Aim: The aim of the study was to describe the corneal endothelial cell ...
Ewete T, Ani EU, Alabi AS
doaj +1 more source
Experimental Eye Research, 2021 Currently, endothelial keratoplasty is the gold standard for the surgical treatment of Fuchs endothelial corneal dystrophy (FECD). Despite the remarkable success in terms of surgical outcomes, a shortage of corneal donor tissue poses a limitation to ...
Bertolin M. +19 more
core +3 more sources
Effects of Aberrant Pax6 Gene Dosage on Mouse Corneal Pathophysiology and Corneal Epithelial Homeostasis [PDF]
, 2011 Background: Altered dosage of the transcription factor PAX6 causes multiple human eye pathophysiologies. PAX6(+/-) heterozygotes suffer from aniridia and aniridia-related keratopathy (ARK), a corneal deterioration that probably involves a limbal ...
Fullwood, Nigel J. +34 more
core +5 more sources
Challenges in Corneal Endothelial Cell Culture
Regenerative Medicine, 2021 Corneal endothelial cells (CECs) facilitate the function of maintaining the transparency of the cornea. Damage or dysfunction of CECs can lead to blindness, and the primary treatment is corneal transplantation. However, the shortage of cornea donors is a significant problem worldwide.
Rintra Wongvisavavit +3 more
openaire +3 more sources
Low Endothelial Cell Count and Clear Corneal Grafts
Indian Journal of Ophthalmology, 2004 Specular microscopic study on clear corneal grafts indicates that at times surprisingly low endothelial cell density can maintain the grafted cornea in a relatively dehydrated state.
Basak Samar
doaj +1 more source
Oligopeptide-mediated gene transfer into mouse corneal endothelial cells: Expression, design optimization, uptake mechanism and nuclear localization [PDF]
, 2009 Copyright © The Author 2009. Published by Oxford University Press. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses?by-nc/2.0/uk/) which permits ...
Seow, WY, George, AJT, Yang, Y-Y
core +1 more source
Overestimation of corneal endothelial cell density by automated method in glaucomatous eyes with impaired corneal endothelial cells [PDF]
International Ophthalmology, 2021 Abstract Purpose To determine between-method differences in corneal endothelial cell parameters using center and automated methods of non-contact specular microscopy (CellCheck software of Konan, Inc.) in glaucomatous eyes. Methods We analyzed the central corneal endothelial
Mayumi Minami, Etsuo Chihara
openaire +2 more sources
Increased Corneal Endothelial Cell Migration in Fuchs Endothelial Corneal Dystrophy
Ophthalmology Science, 2021 To investigate if corneal endothelial cells (CECs) in Fuchs endothelial corneal dystrophy (FECD) have altered cellular migration compared with normal controls.Comparative analysis.Descemet's membrane and CECs derived from patients with FECD undergoing endothelial keratoplasty or normal cadaveric donors.Ex vivo specimens were used for live cell imaging ...
Stephan Ong Tone +5 more
openaire +3 more sources