Potential benefits and risks of clinical xenotransplantation [PDF]
, 2012 The transplantation of organs and cells from pigs into humans could overcome the critical and continuing problem of the lack of availability of deceased human organs and cells for clinical transplantation.
Ayares, D, Cooper, DKC
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Ex vivo expansion of bovine corneal endothelial cells in xeno-free medium supplemented with platelet releasate. [PDF]
PLoS ONE, 2014 Clinical-grade ex vivo expansion of corneal endothelial cells can increase the availability of corneal tissues for transplantation and treatment of corneal blindness. However, these cells have very limited proliferative capacity.
Ming-Li Chou +2 more
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Phenotypic and functional characterization of corneal endothelial cells during in vitro expansion. [PDF]
, 2020 The advent of cell culture-based methods for the establishment and expansion of human corneal endothelial cells (CEnC) has provided a source of transplantable corneal endothelium, with a significant potential to challenge the one donor-one recipient ...
Aldave, Anthony J +14 more
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Minocycline is cytoprotective in human corneal endothelial cells and induces anti-apoptotic B-cell CLL/lymphoma 2 (Bcl-2) and X-linked inhibitor of apoptosis (XIAP) [PDF]
, 2010 Introduction Loss of corneal endothelial cells (CECs) is one major factor limiting transplant clarity and survival after keratoplasty. Amongst other factors, apoptosis due to cellular stress is responsible for these problems.
Hirneiß, Christoph +3 more
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Офтальмохирургия, 2017 Purpose. To assess anatomic topographic parameters of the anterior chamber of the eye in patients with high myopia corrected with the angle-supported phakic intraocular lens (PIOL) of the Cachet design using the anterior segment optical coherence ...
A. A. Shpak +5 more
doaj +1 more source
Regenerative capacity of the corneal transition zone for endothelial cell therapy
Stem Cell Research & Therapy, 2020 The corneal endothelium located on the posterior corneal surface is responsible for regulating stromal hydration. This is contributed by a monolayer of corneal endothelial cells (CECs), which are metabolically active in a continuous fluid-coupled efflux ...
Nicole Ming Sie +6 more
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Corneal changes in soft contact lens wearers
Journal of Clinical Ophthalmology and Research, 2016 There is abundance of physiological and pathological evidence of individual variations in response to soft contact lens wear. Purpose of the study was to observe and to measure changes in corneal curvature, corneal endothelium, corneal thickness and tear-
Reshma Ramakrishnan +2 more
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Effect of corneal light scatter on vision: a review of the literature [PDF]
, 2016 The cornea is the transparent connective tissue window at the front of the eye. The physiological role of the cornea is to conduct external light into the eye, focus it, together with the lens, onto the retina, and to provide rigidity to the entire ...
MARAONE, GIORGIA +4 more
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Evaluation of Corneal Endothelium by Specular Microscopy in Pseudoexfoliation Syndrome
Ahi Evran Medical Journal, 2021 Purpose: To evaluate the corneal endothelium of patients with pseudoexfoliation syndrome (PES) by specular microscopy (SM). Materials and Methods: In this prospective controlled study, two groups were formed, namely the PES group and the control group.
Murat Serkan SONGUR +2 more
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Cx43-hemichannel function and regulation in physiology and pathophysiology: insights from the bovine corneal endothelial cell system and beyond [PDF]
, 2014 Intercellular communication in primary bovine corneal endothelial cells (BCECs) is mainly driven by the release of extracellular ATP through Cx43 hemichannels.
Bultynck, Geert +4 more
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