Results 21 to 30 of about 35,971 (261)
PLoS ONE, 2021 Expansion of CTG trinucleotide repeats (TNR) in the transcription factor 4 (TCF4) gene is highly associated with Fuchs Endothelial Corneal Dystrophy (FECD).
Eric D Wieben +7 more
doaj +1 more source
Feasibility of cell-based therapy combined with descemetorhexis for treating Fuchs endothelial corneal dystrophy in rabbit model. [PDF]
PLoS ONE, 2018 Corneal transparency is maintained by the corneal endothelium through its pump and barrier function. Severe corneal endothelial damage results in dysregulation of water flow and eventually causes corneal haziness and deterioration of visual function.
Naoki Okumura +10 more
doaj +1 more source
Recovery of Corneal Endothelial Cells from Periphery after Injury. [PDF]
PLoS ONE, 2015 Wound healing of the endothelium occurs through cell enlargement and migration. However, the peripheral corneal endothelium may act as a cell resource for the recovery of corneal endothelium in endothelial injury.To investigate the recovery process of ...
Sang Ouk Choi +7 more
doaj +1 more source
Topical rosiglitazone is an effective anti-scarring agent in the cornea [PDF]
, 2013 Corneal scarring remains a major cause of blindness world-wide, with limited treatment options, all of which have side-effects. Here, we tested the hypothesis that topical application of Rosiglitazone, a Thiazolidinedione and ligand of peroxisome ...
Bühren, Jens +8 more
core +10 more sources
Generation and Feasibility Assessment of a New Vehicle for Cell-Based Therapy for Treating Corneal Endothelial Dysfunction. [PDF]
PLoS ONE, 2016 The corneal endothelium maintains corneal transparency by its pump and barrier functions; consequently, its decompensation due to any pathological reason causes severe vision loss due to corneal haziness.
Naoki Okumura +8 more
doaj +1 more source
Corneal endothelial regeneration in human eyes using endothelium-free grafts
BMC Ophthalmology, 2022 Background To report on corneal endothelial regeneration, graft clarity, and vision recovery when using endothelium-free grafts. Methods We evaluated the donor’s cell viability using trypan blue staining and dual staining with calcein acetoxy methyl ...
Lu-Yi Ying +5 more
doaj +1 more source
Evaluation of equine corneal endothelium after exposure to 0.05% brilliant blue - an in vitro study [PDF]
Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2019 The aim of this study was to evaluate the immediate effects of 0.05% brilliant blue on corneal endothelium of horses. Thirty-eight corneas of 19 horses, male or female, of different ages were studied. Corneas were randomly divided into two groups.
M.C.C. Andrade +4 more
doaj +1 more source
Specular microscopy of the corneal endothelial cells of bovines: An ex vivo study
Open Veterinary Journal, 2023 Background: The endothelium is the most posterior layer of the cornea and essential for maintaining corneal transparency. Due to variations in corneal endothelial parameters among different species, knowledge of the normal parameters for each species is
Mariane Gallicchio Azevedo +6 more
doaj +1 more source
Pakistan Armed Forces Medical Journal, 2022 Objective: To evaluate changes in corneal endothelium in patients with anterior uveitis by using specular microscopy and compare it with the corneal endothelium of healthy subjects. Study Design: Comparative cross-sectional study.
Qurat ul Ain Ghazanfar +3 more
doaj +1 more source
Diagnosis and management of iridocorneal endothelial syndrome [PDF]
, 2015 The iridocorneal endothelial (ICE) syndrome is a rare ocular disorder that includes a group of conditions characterized by structural and proliferative abnormalities of the corneal endothelium, the anterior chamber angle, and the iris.
Ambrosio, Oriella +5 more
core +2 more sources