Results 11 to 20 of about 161,416 (241)

Constructing a Novel Three-Dimensional Biomimetic Corneal Endothelium Graft by Culturing Corneal Endothelium Cells on Compressed Collagen Gels

Chinese Medical Journal, 2018
Background: Endothelium allotransplantation is the primary treatment for corneal decompensation. The worldwide shortage of donor corneal tissue has led to increasing pressure to seek an alternative for surgical restoration of corneal endothelium ...
Yu-Jie Cen, Yun Feng
doaj   +2 more sources

Effects of Aberrant Pax6 Gene Dosage on Mouse Corneal Pathophysiology and Corneal Epithelial Homeostasis [PDF]

, 2011
Background: Altered dosage of the transcription factor PAX6 causes multiple human eye pathophysiologies. PAX6(+/-) heterozygotes suffer from aniridia and aniridia-related keratopathy (ARK), a corneal deterioration that probably involves a limbal ...
Fullwood, Nigel J., Martin, Francis L., Collinson, J. Martin, Richard L Mort, Morley, Steven D., Morley Steven D., West John D., Bentley, Adam J., Adam J Bentley, Mort, Richard L, Collinson J. Martin, Panagiotis Douvaras, Collinson, J Martin, J Martin Collinson, Bentley Adam J., Mort Richard L., Martin, Francis L, Bentley, Adam J, Morley, Steven D, Martin Francis L., Douvaras, Panagiotis, Steven D Morley, Robert E Hill, Mort, Richard L., West, John D., Hill, Robert E, Fullwood, Nigel J, Nigel J Fullwood, Douvaras Panagiotis, Fullwood Nigel J., Francis L Martin, Hill Robert E., Hill, Robert E., West, John D, John D West   +34 more
core   +5 more sources

Injury induces endothelial to mesenchymal transition in the mouse corneal endothelium in vivo via FGF2

Molecular Vision, 2019
Purpose: To determine whether the mouse corneal endothelium enters endothelial to mesenchymal transition (EndoMT) following surgical injury in vivo. Methods: The corneal endothelium in anesthetized mice was surgically injured in vivo under direct ...
JeongGoo Lee, Eric Jung, Martin Heur
doaj   +1 more source

Feasibility of cell-based therapy combined with descemetorhexis for treating Fuchs endothelial corneal dystrophy in rabbit model. [PDF]

PLoS ONE, 2018
Corneal transparency is maintained by the corneal endothelium through its pump and barrier function. Severe corneal endothelial damage results in dysregulation of water flow and eventually causes corneal haziness and deterioration of visual function.
Naoki Okumura, Daiki Matsumoto, Yuya Fukui, Masataka Teramoto, Hirofumi Imai, Tetta Kurosawa, Tomoki Shimada, Friedrich Kruse, Ursula Schlötzer-Schrehardt, Shigeru Kinoshita, Noriko Koizumi   +10 more
doaj   +1 more source

Recovery of Corneal Endothelial Cells from Periphery after Injury. [PDF]

PLoS ONE, 2015
Wound healing of the endothelium occurs through cell enlargement and migration. However, the peripheral corneal endothelium may act as a cell resource for the recovery of corneal endothelium in endothelial injury.To investigate the recovery process of ...
Sang Ouk Choi, Hyun Sun Jeon, Joon Young Hyon, Yun-Jung Oh, Won Ryang Wee, Tae-Young Chung, Young Joo Shin, Jeong Won Kim   +7 more
doaj   +1 more source

Generation and Feasibility Assessment of a New Vehicle for Cell-Based Therapy for Treating Corneal Endothelial Dysfunction. [PDF]

PLoS ONE, 2016
The corneal endothelium maintains corneal transparency by its pump and barrier functions; consequently, its decompensation due to any pathological reason causes severe vision loss due to corneal haziness.
Naoki Okumura, Kazuya Kakutani, Ryota Inoue, Daiki Matsumoto, Tomoki Shimada, Makiko Nakahara, Yumiko Kiyanagi, Takehiro Itoh, Noriko Koizumi   +8 more
doaj   +1 more source

Corneal endothelial regeneration in human eyes using endothelium-free grafts

BMC Ophthalmology, 2022
Background To report on corneal endothelial regeneration, graft clarity, and vision recovery when using endothelium-free grafts. Methods We evaluated the donor’s cell viability using trypan blue staining and dual staining with calcein acetoxy methyl ...
Lu-Yi Ying, Wen-Ya Qiu, Bing-Hong Wang, Ping Zhou, Bei Zhang, Yu-Feng Yao   +5 more
doaj   +1 more source

Evaluation of equine corneal endothelium after exposure to 0.05% brilliant blue - an in vitro study [PDF]

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2019
The aim of this study was to evaluate the immediate effects of 0.05% brilliant blue on corneal endothelium of horses. Thirty-eight corneas of 19 horses, male or female, of different ages were studied. Corneas were randomly divided into two groups.
M.C.C. Andrade, T.M. Moreno, M.S. Muccillo, J.A.T. Pigatto, E.V. Camilo   +4 more
doaj   +1 more source

<i>Herpesvirus</i> Infections of the Corneal Endothelium. [PDF]

Microorganisms
Corneal endotheliitis is an inflammatory process, most commonly of viral etiology, that manifests clinically with features including corneal edema, keratic precipitates, and a mild anterior chamber reaction.
Wang J, Rabiee B, Patel C, Jafri M, Hussain H, Chaudhry A, Chaudhry I, Kamoun L, Chaudhry I, Oh L, Bobat FI, Shukla D, Farooq AV.   +12 more
europepmc   +2 more sources

Specular microscopy of the corneal endothelial cells of bovines: An ex vivo study

Open Veterinary Journal, 2023
Background: The endothelium is the most posterior layer of the cornea and essential for maintaining corneal transparency. Due to variations in corneal endothelial parameters among different species, knowledge of the normal parameters for each species is
Mariane Gallicchio Azevedo, Natalia Pons Mendez, Luísa Soares Cargnin, Rafaella Silva Rocha, Maiara Poersch Seibel, Alessandra Fernandez da Silva, Joao Antonio Tadeu Pigatto   +6 more
doaj   +1 more source