Results 71 to 80 of about 161,416 (241)

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

Medicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli, Alessia Merra, Chiara Marraccini, Lucia Merolle, Graziella Pellegrini, Eleonora Maurizi   +5 more
wiley   +1 more source

Busin Glide-Assisted Pull-Through Insertion of Artificial Corneal Endothelium (EndoArt). [PDF]

Int Med Case Rep J
Akira Kobayashi,1 Takahiko Hayashi,2 Ami Igarashi,2 Toshiki Shimizu,2 Hideaki Yokogawa,1 Kentaro Yuda,3 Björn Bachmann,4 Satoru Yamagami,2 Kazuhisa Sugiyama1 1Department of Ophthalmology, Kanazawa University Hospital, Ishikawa, Japan; 2Department of ...
Kobayashi A, Hayashi T, Igarashi A, Shimizu T, Yokogawa H, Yuda K, Bachmann B, Yamagami S, Sugiyama K.   +8 more
europepmc   +2 more sources

Plant‐derived nanovesicles as potential drug delivery systems for topical use: Emerging applications in dermatology and cosmetology

VIEW, EarlyView.
Plant‐derived nanovesicles (PDNVs) are naturally secreted by fruit, vegetables, seeds, leaves and other natural sources. Used as drug delivery systems, they can combine intrinsic therapeutic activity, enhanced skin permeation and cargo‐carrying capacity, suitable for dermatological and cosmetic applications including hydration, antioxidant/anti ...
Dorotea Fiore, Beatrice Pellegrini, Antonia Mancuso, Maria Chiara Cristiano, Salvatore Panza, Donatella Paolino   +5 more
wiley   +1 more source

Development of a tissue engineered corneal endothelium

, 2023
Normal corneal endothelial cells are pivotal in maintaining the cornea's transparency. Limited in vivo cell proliferative capacity results in a corneal endothelium that cannot regenerate to compensate for natural or acquired cell density loss. Therefore,
Tsai, Meng-Chen
core   +1 more source

Expression of MUC1 on corneal endothelium of human

, 2021
Purpose. To determine the expression of MUC1 in the human corneal endothelium. Methods. Reverse transcription-polymerase chain reaction (RT-PCR) for MUC1 was performed with total RNA from endothelial cells extracted from the human cornea.
김형래
core   +1 more source

Assessing a Model for a Complex Systemic Disorder—The Value of Male Mice With a Supernumerary X Chromosome for Klinefelter Syndrome Research

Andrology, EarlyView.
ABSTRACT Introduction Direct experimental investigation of Klinefelter syndrome (KS) in patients is limited because the syndrome manifests heterogeneously and affects multiple organ systems. Studying KS therefore requires a model that captures this complexity as accurately as possible while still permitting controlled experimental manipulation ...
Fariba Saadati, Joachim Wistuba
wiley   +1 more source

Effects of Laser In Situ Keratomileusis on the Corneal Endothelium

Kaohsiung Journal of Medical Sciences, 2005
The purpose of this study was to assess the effects of laser in situ keratomileusis (LASIK) on the corneal endothelium. In a prospective study, the corneal endothelium of 87 eyes (45 patients) was examined before and 1 month after LASIK.
Chun-Chi Chiang, Jane-Ming Lin, Pei-Jane Bair, Wen-Lu Chen, Yi-Yu Tsai   +4 more
doaj   +1 more source

Effects of Contact Lenses on Corneal Endothelium - a Morphological and Functional Study

, 2009
Purpose: To study the corneal endothelial morphological changes and endothelial barrier function in contact lens wearers. Methods: Specular microscopy and anterior segment fluorophotometry were performed on 116 controls (group 1) and 76 daily wear soft ...
胡芳蓉;林隆光, HU, FUNG-RONG;LIN, LUKE LONG-KUANG   +1 more
core  

Corneal endothelium: Developmental strategies for regeneration

, 2013
The main treatment available for restoration of the corneal endothelium is keratoplasty. This procedure is faced with several difficulties, including the shortage of donor tissue, post-surgical complications associated with the use of drugs to prevent ...
Valdez-Garcia, J., Zavala, J., Lopez Jaime, G.R., Rodriguez Barrientos, C.A.   +3 more
core   +1 more source

Infectious bacterial keratitis management in a Swedish region: Risk factors, treatment and time‐to‐resolution

Acta Ophthalmologica, EarlyView.
Abstract Purpose To report treatment patterns, time‐to‐resolution (TTR) and aetiologies of bacterial keratitis (BK) infections treated in a specialized hospital‐based cornea clinic in Sweden. Methods Retrospective study based on electronic health records screened during the period 2010–2019. The study included only culture‐confirmed cases of BK.
Jenny Roth, Antonio Filipe Macedo, Sofia Somajo, Lukas Tannerfeldt, Baris Toprak, Neil Lagali   +5 more
wiley   +1 more source