Results 91 to 100 of about 161,416 (241)

Childhood ocular safety after postnatal exposure to topical dexamethasone during retinopathy of prematurity screening

Acta Ophthalmologica, EarlyView.
Abstract Purpose Dexamethasone eye drops are being introduced off‐label to prevent progression of severe retinopathy of prematurity (ROP). We evaluated ophthalmologic outcomes in early childhood after postnatal topical dexamethasone exposure in pre‐term infants at a standardized follow‐up examination.
Mariya Petrishka‐Lozenska, Anders K. Nilsson, Ann Hellström, Pia Lundgren   +3 more
wiley   +1 more source

Corneal endothelium and central corneal thickness changes in type 2 diabetes mellitus

, 2017
Amira El-Agamy,1,2,* Shams Alsubaie3,* 1Department of Optometry and Vision Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia; 2Mansoura Ophthalmic Center, Faculty of Medicine, Mansoura University, Mansoura, Egypt;
El-Agamy A, Alsubaie S
core  

Clinical outcomes of the PAUL® glaucoma implant for secondary glaucoma

Acta Ophthalmologica, EarlyView.
Abstract Purpose Secondary glaucoma encompasses a broad spectrum of disease entities arising from diverse ocular pathologies and is often refractory to conventional treatment. Glaucoma drainage devices (GDDs) have therefore become an important surgical option.
Carolin Deubel, Benjamin Aretz, Wolfgang Walz, Michael Petrak, Frank G. Holz, Raffael Liegl, Karl Mercieca, Constance Liegl   +7 more
wiley   +1 more source

Towards Clinical Application: Calcium Waves for In Vitro Qualitative Assessment of Propagated Primary Human Corneal Endothelial Cells

Cells
Corneal endothelium cells (CECs) regulate corneal hydration between the leaky barrier of the corneal endothelium and the ionic pumps on the surface of CECs. As CECs do not regenerate, loss of CECs leads to poor vision and corneal blindness.
Xiao Yu Ng, Gary Peh, Fernando Morales-Wong, Rami Gabriel, Poh Loong Soong, Kun-Han Lin, Jodhbir S. Mehta   +6 more
doaj   +1 more source

Prostaglandin-inhibitor naproxen does not affect contact lens-induced changes in the human corneal endothelium

, 1984
A randomized, double-masked, placebo-controlled study was conducted to determine the effect of the prostaglandin-inhibitor naproxen on the bleb response of the corneal endothelium during hydrogel contact lens wear.
Holden, Brien A., Efron, Nathan, Vannas, Antti   +2 more
core  

Optic nerve head blood flow autoregulation during isometric exercise in primary open‐angle glaucoma assessed by laser speckle flowgraphy

Acta Ophthalmologica, EarlyView.
Abstract Purpose To assess optic nerve head blood flow (ONHBF) autoregulation in patients with early‐ to moderate‐stage primary open‐angle glaucoma (POAG) and age‐ and sex‐matched healthy controls using laser speckle flowgraphy (LSFG) and isometric handgrip exercise.
Theresa Lindner, Viktoria Pai, Patrick Janku, Nikolaus Hommer, Anton Hommer, Liudmyla Petric, Ulrich Graf, Leopold Schmetterer, Gerhard Garhöfer, Doreen Schmidl   +9 more
wiley   +1 more source

Blockade of mitochondrial components release by exosome pathway promotes the pathogenesis of Fuchs endothelial corneal dystrophy

Cell Death Discovery
Fuchs endothelial corneal dystrophy (FECD) is the leading indication of corneal transplantation worldwide and the focus of pathogenesis has been on the corneal endothelium. Instead of cellular analysis, we aimed to identify the protein changes of aqueous
Can Zhao, Qun Wang, Qingjun Zhou, Zhiqing Wang, Shuangqing Yao, Tian Sang, Haoyun Duan, Jingyi Wu, Xiaowei Zhong, Xin Sui, Weiyun Shi, Ting Wang   +11 more
doaj   +1 more source

Peripheral targets for neuropathic pain

British Journal of Pharmacology, EarlyView.
Neuropathic pain represents a significant clinical challenge, with still limited pharmacological approaches to symptomatic relief. This review focuses on molecular targets implicated in neuropathic pain, particularly those involved in peripheral mechanisms. Using the IUPHAR/BPS database of biological targets, their occurrence together with ‘neuropathic
Amirhossein Afsharipour, Cosmin I. Ciotu, Felix J. Resch, Michael J. M. Fischer   +3 more
wiley   +1 more source

Research progress of corneal endothelial cell regeneration and replacement

Eye & ENT Research
Corneal endothelial cells (CECs) are crucial for the maintenance of corneal transparency and normal visual function. Corneal endothelial dysfunction can lead to corneal edema, opacity, and even blindness.
Zongyi Li, Haoyun Duan, Qingjun Zhou
doaj   +1 more source

Birefringent properties of the human cornea in vivo : towards a new model of corneal structure [PDF]

The fundamental corneal properties of mechanical rigidity, maintenance of curvature and optical transparency result from the specific organisation of collagen fibrils in the corneal stroma. The exact arrangement of stromal collagen is currently unknown
Misson, Gary P.
core