Results 61 to 70 of about 16,319 (140)
Epidermal necrolysis sequelae: A cohort study on prevalence and risk factors
Long‐term sequelae after epidermal necrolysis are frequent, multiple and often severe. Cutaneous, ocular and psychological complications are more frequent, with significant socioeconomic impact. Cluster analysis identifies distinct patient profiles, highlighting the need for personalized multidisciplinary follow‐up.
Thanh Vy Nguyen +9 more
wiley +1 more source
Abstract Corneal reconstruction is a key part of veterinary ophthalmic practice and numerous reconstructive techniques have been described for use in small animals in the peer‐reviewed veterinary literature written in English. Despite the evidence accrued over the last six decades in over 40 clinical articles and numerous other publications on ocular ...
Rick F. Sanchez +2 more
wiley +1 more source
Quantification of corneal neovascularization after ex vivo limbal epithelial stem cell therapy
AIM: To assess cultured limbal epithelial stem cell transplantation in patients with limbal stem cell deficiency by analyzing and quantifying corneal neovascularization.METHODS: This retrospective, interventional case series included eight eyes with ...
Adriano Guarnieri +6 more
doaj +1 more source
Ocular Manifestations of Metabolic Syndrome: A Systemic Vascular Phenotype
ABSTRACT Context Metabolic syndrome (MetS) is defined by central obesity, insulin resistance, hypertension and dyslipidemia. MetS affects over one‐third of US adults. Beyond its cardiovascular burden, MetS has clinically relevant associations with ocular health and may contribute to a systemic vascular and neuro‐metabolic phenotype involving the retina,
Ron T. Varghese, Ansu A. John
wiley +1 more source
Corneal Sequestration and Bilateral Distichiasis in a Binturong (Arctictis binturong)
ABSTRACT Objective To report the first documented case of corneal sequestration and distichiasis in a binturong (Arctictis binturong), discuss implications of disease prevalence in a non‐domestic feliform, and hypothesize on potential etiology and predisposing factors for corneal sequestration.
Vienna Lunking +7 more
wiley +1 more source
ABSTRACT Purpose To describe cases of canine idiopathic periocular granulomatous inflammation. Material and Methods Clinical records were reviewed. Animal Studied At the time of presentation, the four patients (German Shepherd dog, mixed breed, Magyar Vizsla, Hovawart) were 1.5–5 (mean 3.75) years old. All dogs were female; two were spayed.
J. Kurwinkel +5 more
wiley +1 more source
From Molecular Targets to Advanced Delivery Systems: Aptamers for Precision Ocular Therapeutics
Aptamer‐based strategies are revolutionizing ocular disease management through highly specific molecular recognition of disease specific molecular targets. This review systematically integrates therapeutic aptamer sequences, diagnostic aptasensor platforms, and targeted delivery strategies, highlighting design principles, ocular bioavailability ...
Minal Thacker +4 more
wiley +1 more source
In bladder cancer, LRG1 binds to ANXA2 to trigger mitochondrial ROS‐dependent NETosis. This pathogenic cascade actively uncouples endothelial‐mural cell interactions, driving profound vascular destabilization. Consequently, targeting the LRG1‐ANXA2 axis attenuates the neutrophil burden and induces structural vascular normalization, offering a powerful ...
Dongshan Chen +8 more
wiley +1 more source
Short‐Chain Fatty Acids: Microbial Metabolites Driving Gut‐Eye Axis Signaling
Short‐chain fatty acids generated by gut microbial fermentation link diet to ocular physiology via the gut–eye axis. Through systemic distribution, these metabolites regulate GPCR signaling, epigenetic pathways, inflammation, and angiogenesis, shaping retinal homeostasis and highlighting therapeutic potential in ocular vascular and inflammatory ...
Aleah J. Brokemond +6 more
wiley +1 more source
Multifunctional Hydrogels: Rational Design and Application in Regenerative Medicine
Multifunctional hydrogels represent a paradigm shift in regenerative medicine, integrating rational material design with bioactive functionality to address complex tissue repair challenges. This review systematically examines the molecular engineering, structure–function relationships, and translational landscape of advanced hydrogel systems, spanning ...
Linyang Song +4 more
wiley +1 more source

