Corneal Stroma Regeneration with Acellular Corneal Stroma Sheets and Keratocytes in a Rabbit Model. [PDF]
PLoS ONE, 2015 Acellular corneal stroma matrix has been used for corneal stroma engineering. However, because of its compact tissue structure, regrowth of keratocytes into the scaffold is difficult.
Xiao Yun Ma +7 more
doaj +5 more sources
Lamellar Keratoplasty Using Acellular Porcine Corneal Stroma for the Treatment of Corneal Ulcers [PDF]
Frontiers in MedicineObjectiveThe study aimed to investigate the efficacy and safety of acellular porcine corneal stroma (APCS) for lamellar keratoplasty in the treatment of corneal ulcers.MethodsA total of 14 patients (14 eyes) diagnosed with corneal ulcers who underwent ...
Zhirong Lin, Qifang Jin, Yiming Hu
exaly +4 more sources
Nerve influence on the metabolism of type I and type II diabetic corneal stroma: an in vitro study [PDF]
Scientific Reports, 2021 Corneal innervation plays a major role in the pathobiology of diabetic corneal disease. However, innervation impact has mainly been investigated in the context of diabetic epitheliopathy and wound healing.
Amy E. Whelchel +3 more
doaj +3 more sources
Application Prospect and Preliminary Exploration of GelMA in Corneal Stroma Regeneration [PDF]
Polymers, 2022 Corneal regeneration has become a prominent study area in recent decades. Because the corneal stroma contributes about 90% of the corneal thickness in the corneal structure, corneal stromal regeneration is critical for the treatment of cornea disease ...
Lingjuan Xu, Guigang Li, Guanyu Su
exaly +3 more sources
RHO-Associated Coiled-Coil-Containing Protein Kinase Inhibitors Significantly Modulate the Epithelial–Mesenchymal Transition Induced by TGF-β2 in the 2-D and 3-D Cultures of Human Corneal Stroma Fibroblasts [PDF]
BiomedicinesBackground/Objectives: The objective of the present study was to examine the unidentified effects that RHO-associated coiled-coil-containing protein kinase 1 and 2 antagonists exert on the transforming growth factor beta2-induced epithelial–mesenchymal ...
Araya Umetsu +7 more
doaj +2 more sources
Decellularized squid mantle scaffolds as tissue‐engineered corneal stroma for promoting corneal regeneration [PDF]
Bioengineering & Translational Medicine, 2023 Corneal blindness is a worldwide major cause of vision loss, and corneal transplantation remains to be the most effective way to restore the vision. However, often there is a shortage of the donor corneas for transplantation.
Honghua Kang +7 more
doaj +2 more sources
Novel strategy for multi-material 3D bioprinting of human stem cell based corneal stroma with heterogenous design [PDF]
Materials Today BioThree-dimensional (3D) bioprinting offers an automated, customizable solution to manufacture highly detailed 3D tissue constructs and holds great promise for regenerative medicine to solve the severe global shortage of donor tissues and organs.
Paula Puistola +3 more
doaj +2 more sources
Case Reports in Ophthalmology, 2021 Accidental intraocular lens (IOL) implantation into the corneal stroma is a rare clinical entity that can occur during the wound-assisted technique. In this report, we describe a case of an 81-year-old man who underwent cataract surgery in which the IOL ...
Jo Moriya +4 more
doaj +1 more source
STAR Protocols, 2023 Summary: Existing flow cytometry approaches identify immune cells using the whole infected/inflamed cornea, which limits its ability to distinguish the immune cells infiltrating the corneal epithelium from the corneal stroma.
Mizumi Setia +2 more
doaj +1 more source
Hydrogels Derived From Acellular Porcine Corneal Stroma Enhance Corneal Wound Healing [PDF]
Acta Biomaterialia, 2021 Joy Sarkar +2 more
exaly +2 more sources