Results 41 to 50 of about 147,554 (211)

Low‐intensity low‐frequency ultrasound mediates riboflavin delivery during corneal crosslinking

Bioengineering & Translational Medicine, 2023
We employed the mechanical effect from 40 kHz ultrasound (US) to improve the delivery of riboflavin into corneal stroma for collagen crosslinking, which can benefit the treatment of keratoconus and other corneal ectasias.
Zhe Sun, Zhiming Li, Jin Teng Chung, Laurence Chi Ming Lau, Vishal Jhanji, Ying Chau   +5 more
doaj   +1 more source

Transparency, swelling and scarring in the corneal stroma [PDF]

Eye, 2003
This paper briefly reviews current explanations for corneal transparency and uses a well-developed model to try to explain the increased light scattering either accompanying corneal swelling or following phototherapeutic keratectomy (PTK).The direct summation of fields (DSF) method was used to compute light transmission as a function of wavelength. The
Meek, Keith Michael Andrew, Leonard, D., Connon, Che John, Hayes, Sally, Khan, S.   +4 more
openaire   +3 more sources

The use of innovative scaffolds in the development of corneal stroma-derived stem cell therapies for future corneal regeneration strategies [Abstract] [PDF]

, 2015
The use of innovative scaffolds in the development of corneal stroma-derived stem cell therapies for future corneal regeneration strategies ...
Siobhan E. Dunphy (7210592), Matthew J. Branch (7210091), Laura E. Sidney (7210094), Sammy Wilson (1259568), Felicity R.A.J. Rose (7162868), Harminder S. Dua (478202), Andrew Hopkinson (346771)   +6 more
core   +3 more sources

A ROS‐Responsive and Mucoadhesive Thermosensitive Hydrogel Encapsulated with Mizoribine for Synergistic Dry Eye Therapy

Advanced Science, EarlyView.
The ROS‐responsive in situ thermosensitive MZR@SPPP hydrogel system enables dual‐stage drug loading and sustained ocular delivery. Upon administration, it gelates at ocular surface temperature, enhancing ocular adhesion. By scavenging free radicals, restoring NRF2‐mediated antioxidant defense and mitochondrial homeostasis, and suppressing inflammatory ...
Danyi Qin, Jiani Li, Panqin Ma, Shinan Wu, Wenying Guan, Yimin Huang, Ke Feng, Mingyan Wei, Zixuan Yang, Shujia Guo, Caihong Huang, Yun‐Long Wu, Yi Han, Zuguo Liu   +13 more
wiley   +1 more source

Dual‐Dynamically Crosslinked Nanogels Enable Prolonged Ocular Retention for Multimodal Dry Eye Therapy

Advanced Science, EarlyView.
This berberine‐loaded dual‐dynamically crosslinked nanogel integrates tannic acid‐zinc metal‐phenolic networks and carboxymethyl chitosan/aldehyde‐functionalized poly(ethylene glycol) dynamic Schiff base networks, achieving 1‐year colloidal and antioxidant stability, sustained corneal berberine exposure for 24 h to support convenient once‐daily dosing,
Yanru Xin, Sisi Chen, Shengli Huang, Mengqi Huang, Jingyan Zhu, Zijian Wang, Jianliang Shen, Qinxiang Zheng   +7 more
wiley   +1 more source

Using nanotopography and macromolecular crowding to influence in vitro collagen deposition in a corneal stroma model [PDF]

, 2021
The corneal stroma is a transparent and avascular tissue constituting 90% of the cornea. The stroma comprises collagenous lamellae, oriented roughly orthogonally, and is populated by quiescent keratocytes.
O'Loughlin, Danielle
core   +1 more source

Ocular morphology and morphometry of the great egret (Ardea alba): A comprehensive anatomical description

The Anatomical Record, EarlyView.
Abstract Ardea alba (Linnaeus, 1758) is widely distributed, yet knowledge of its ocular morphology remains limited. This study described the morphometry and morphology of the eyeball and its accessory glands in six specimens using radiography, morphometry, light and scanning electron microscopy, and 3D scanning.
Julia Vaz Feio, Max Alex Santos Ferreira, Iara Fernanda Lima do Espírito Santo, Elane Guerreiro Giese, Érika Branco, Antônio Basílio Guerreiro Junior, Ana Rita de Lima   +6 more
wiley   +1 more source

In vitro tissue engineering of lamellar cornea using human amniotic epithelial cells and rabbit cornea stroma [PDF]

International Journal of Ophthalmology, 2013
AIM:To reconstruct the lamellar cornea using human amniotic epithelial (HAE) cells and rabbit cornea stroma in vitro using tissue engineering technology.METHODS: Human amnia taken from uncomplicated caesarean sections were digested by collagenase to ...
Xiao-Yong Liu, Jian Chen, Qing Zhou, Jing Wu, Xiao-Ling Zhang, Li Wang, Xiao-Yan Qin   +6 more
doaj   +1 more source

3D printed biomimetic epithelium/stroma bilayer hydrogel implant for corneal regeneration

Bioactive Materials, 2022
Corneal regeneration has always been a challenge due to its sophisticated structure and undesirable keratocyte-fibroblast transformation. Herein, we propose 3D printing of a biomimetic epithelium/stroma bilayer implant for corneal regeneration.
Binbin He, Jie Wang, Mengtian Xie, Miaoyi Xu, Yahan Zhang, Huijie Hao, Xiaoli Xing, William Lu, Quanhong Han, Wenguang Liu   +9 more
doaj   +1 more source

The architecture of the corneal stroma [PDF]

British Journal of Ophthalmology, 2001
In recent years the evolution of modern refractive surgery has focused attention on the architecture and biological properties of the cornea. In this issue of the BJO (p 437) Muller et al address the differential behaviour of the anterior and posterior stroma during corneal swelling and draw interesting conclusions about the factors maintaining corneal
openaire   +1 more source