Results 41 to 50 of about 143,538 (238)

Upregulation of 5-hydroxytryptamine receptor signaling in coronary arteries after organ culture. [PDF]

PLoS ONE, 2014
5-Hydroxytryptamine (5-HT) is a powerful constrictor of coronary arteries and is considered to be involved in the pathophysiological mechanisms of coronary-artery spasm. However, the mechanism of enhancement of coronary-artery constriction to 5-HT during
Chun-Yu Deng, Hui Yang, Su-Juan Kuang, Fang Rao, Yu-Mei Xue, Zhi-Ling Zhou, Xiao-Ying Liu, Zhi-Xin Shan, Xiao-Hong Li, Qiu-Xiong Lin, Shu-Lin Wu, Xi-Yong Yu   +11 more
doaj   +1 more source

Patient‐Derived 3D Heart‐On‐a‐Chip Model of Dilated Cardiomyopathy With Embedded Bead‐Based Mapping of Tissue Contractility

Advanced Healthcare Materials, EarlyView.
A heart‐on‐a‐chip model of dilated cardiomyopathy is developed from patient‐derived induced pluripotent stem cells. The model recapitulates key disease phenotypes and enables functional assessment through integrated bead‐based tracking and pillar deflection measurements.
Ali Mousavi, Ludovic Mouttet, Shihao Cui, Yasaman Hekmatnia, Mehran Mottahedi, Ida Derish, Naimeh Rafatian, Mark Aurousseau, Gregor Andelfinger, Renzo Cecere, Houman Savoji   +10 more
wiley   +1 more source

Coronary artery calcium

Journal of Cardiovascular Computed Tomography, 2019
Coronary artery calcium (CAC) is a strong predictor for future cardiovascular events. Traditionally CAC has been quantified using the Agatston score, which was developed in the late 1980s for electron beam tomography (EBT). While EBT has been completely replaced by modern multiple-detector row CT technology, the traditional CAC scoring method by ...
Willemink, Martin J, van der Werf, Niels R, Nieman, Koen, Greuter, Marcel J W, Koweek, Lynne M, Fleischmann, Dominik   +5 more
openaire   +2 more sources

Gender and age effects on coronary calcium index in patients with suspected CHD

Наука и инновации в медицине
Aim – to assess the influence of sex and age on the coronary artery calcium (CAC) score in patients with suspected coronary heart disease (CHD). Material and methods. A prospective, observational, single-center study was conducted.
P. R. Shatskaya, Olesya A. Rubanenko, Irina Zolotovskaya, Elena V. Adonina, Dmitry V. Duplyakov   +4 more
doaj   +1 more source

Management of Coronary Artery Calcium and Coronary CTA Findings [PDF]

Current Cardiovascular Imaging Reports, 2015
Coronary artery calcium (CAC) testing and coronary computed tomography angiography (CTA) have significant data supporting their ability to identify coronary artery disease (CAD) and classify patient risk for atherosclerotic cardiovascular disease (ASCVD).
Thomas, Dustin M., Villines, Todd C., Nasir, Khurram, Slim, Ahmad M., Divakaran, Sanjay, Shah, Nishant R., Blankstein, Ron, Cheezum, Michael K.   +7 more
openaire   +4 more sources

Nanomaterial Strategies for Pulmonary Delivery of Immunotherapeutics in Lung Cancer Treatment

Advanced Healthcare Materials, EarlyView.
Inhalable immunotherapeutic nanomedicines enable organ‐selective immune modulation by overcoming pulmonary delivery barriers and concentrating therapy within lung tumors. This Review defines how nanomaterial properties govern airway deposition, retention, cellular partitioning, and immune activation across vaccines, checkpoint blockade, STING agonists,
Han Zhang, Wei Tang
wiley   +1 more source

Evaluation of the Relation between Serum Level of High-Sensitivity Reactive Protein (HS-CRP) and Coronary Calcification with the Presence of Coronary Artery Disease in Computed Tomography Angiography

مجله دانشکده پزشکی اصفهان, 2019
Background: Some studies showed that two factors of calcium score and high-sensitivity C-reactive protein (HS-CRP) are related with coronary artery disease, but no definitive theory has been provided.
Amirreza Sajjadieh, Alireza Arefpour
doaj   +1 more source

Unstable Coronary Plaque and Its Relation to Coronary Calcium [PDF]

Circulation, 2001
Coronary calcium is intimately associated with coronary atherosclerotic plaque development. The use of electron-beam computed tomography (EBCT) for accurate quantitative measurements has led to an increased interest in understanding the clinical importance of coronary calcium, particularly in terms of the ability to identify unstable coronary plaques ...
A, Schmermund, R, Erbel
openaire   +2 more sources

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

Advanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

Investigating the Relationship between Calcium Score in Coronary Arteries and Aortic Valve in Predicting the Risk of Cardiovascular Events on Cardiac Computed Tomography Angiography [PDF]

پزشکی بالینی ابن سینا
Background and Objective: Coronary artery and aortic valve calcium measurement is a low-cost, fast, and without the need for injection of contrast media, which is important in determining the severity of atherosclerosis and the prognosis of heart disease.
Seyed Kamaledin Hadei, Mina Azhand, Farnaz Fariba   +2 more
doaj