Results 51 to 60 of about 143,538 (238)

Lipid Nanoparticle Co‐Delivery of mRNA and a Small Molecule Drug for Oral Cancer Chemoimmunotherapy

Advanced Materials, EarlyView.
Co‐encapsulation of p53 mRNA and the small molecule ciclopirox within a lipid nanoparticle yields an all‐in‐one chemoimmunotherapy for oral squamous cell carcinoma. The platform engages caspase‐driven apoptosis in cancer cells while repolarizing tumor‐associated macrophages, achieving tumor reduction in both p53‐susceptible and p53‐resistant models and
Marshall S. Padilla, Jacqueline J. Li, Qunzhou Zhang, Korey Patwari, Shihong Shi, Hannah M. Yamagata, Ryann A. Joseph, Briyanna N. Hymms, Sridatta V. Teerdhala, Emily Fitzgerald, Ori Z. Chalom, Kushol Gupta, Mohamad‐Gabriel Alameh, Drew Weissman, Anh D. Le, Michael J. Mitchell   +15 more
wiley   +1 more source

Validity of the coronary calcium volume in the diagnosis of the significant coronary stenosis.

Revista Cubana de Cardiología y Cirugía Cardiovascular, 2011
The presence of calcium in coronary arteries confirms the presence of atherosclerosis.To determine the validity of coronary calcium(Ca) total volume by the Callister´s method in the diagnosis of significant coronary stenosis.A descriptive transversal ...
Sandra M. Pérez Ruiz, Vladimir Mendoza Rodríguez, Luis R. Llerena Rojas, Fausto Fabián Crespo, Eddy W. Olivares Aquiles   +4 more
doaj  

Recent Advances in Ferrite‐Based Materials for Biomedical Applications: A Comprehensive Review

Advanced Materials, EarlyView.
Ferrite nanoplatforms are presented as tunable biomedical materials in which synthesis control, cation engineering, defect/morphology regulation, and surface functionalization govern structure–property–bioactivity relationships. These design strategies enable multifunctional applications including MRI contrast, magnetic hyperthermia, targeted drug ...
Pramod D. Mhase, Varsha C. Pujari, Akash V. Fulari, Sunil M. Patange, Sean Li, Danyang Wang, Sagar E. Shirsath   +6 more
wiley   +1 more source

High‐Entropy Ceramic‐Enhanced Deformable Triboelectric Nanogenerator for Noncontact Biomechanical and Raindrop Energy Harvesting

Advanced Materials, EarlyView.
A large‐area, deformable high‐entropy‐ceramic (HEC)‐doped triboelectric nanogenerator with a trilayer architecture is developed, consisting of an HEC‐doped triboelectric layer, a graphite‐like textile charge‐storage layer, and stretchable carbon black electrodes.
Shengyou Li, Wei‐Chen Peng, Syun‐Hong Chou, Zhi‐Xian Yan, Jiann‐Yeu Chen, Dun‐Jie Jhan, Wei‐Chun Yang, Shi‐Hong Chen, Yi‐Lin Huang, Cheng‐Hung Tsai, Ming‐Yen Lu, Heng‐Jui Liu, Cheolmin Park, Ying‐Chih Lai   +13 more
wiley   +1 more source

Programmable Functional Silicification of DNA Origami Nanostructures

Advanced Materials, EarlyView.
This work introduces additional functionality into silica‐coated DNA origami nanostructures using non‐standard silica precursors. A fluorescent precursor enables enhanced intracellular tracking, while a disulfide‐containing reagent yields redox‐responsive, degradable silica coatings.
Anna V. Baptist, Lasse Guericke, Philipp Mauker, Oliver Thorn‐Seshold, Amelie Heuer‐Jungemann   +4 more
wiley   +1 more source

Negotiating in a Foreign Land: Understanding the Curious Interactions Between Intracellular Mitochondria and Internalized Nanoparticles

Advanced Materials Interfaces, EarlyView.
Therapeutic nano‐drug delivery systems interact with cellular mitochondria in a multitude of ways. While the complexity of such interactions disrupts the mitochondrial electron transport chain and increases reactive oxygen species production, thereby contributing to nanoparticle toxicity, they also present unique theranostic opportunities in diseases ...
Sourav Bhattacharjee
wiley   +1 more source

Cognitive deficits and coronary calcium levels in hypertension on the background of bronchial asthma

Лечащий Врач
Background. The article presents the results of a study to identify cognitive deficits in patients based on the level of coronary calcium with concomitant pathology in the form of hypertension and bronchial asthma.
L. A. Mubinova, V. A. Razin
doaj   +1 more source

Implications of Gender Difference in Coronary Calcification as Assessed by CT Coronary Angiography

Clinical Medicine Insights: Cardiology, 2014
Background Arterial calcium as measured by 64-slice computed tomography coronary angiography (64-CT) is a reliable predictor of cardiovascular disease risk. Lipid-rich plaques with lower degrees of calcification may pose greater risk for adverse coronary
Amgad N. Makaryus, Cristina Sison, Michelle Kohansieh, John N. Makaryus   +3 more
doaj   +1 more source

Surface‐Anchored Microgel‐Based Films as Anti‐Icing Coatings

Advanced Materials Interfaces, EarlyView.
The microgel‐based anti‐icing coatings presented in this work reduce ice adhesion by up to 90% on various substrates. This effect can be attributed to the incorporated functional cationic moieties binding a lubricating layer of quasi‐liquid interfacial water.
Inga Litzen, Jacek J. Walkowiak, Steven Zimmer, Meike Emondts, Rostislav Vinokur, Isabel K. Sommerfeld, Philippe Schumacher, Henk Schönheit, Dan E. Demco, Andrij Pich   +9 more
wiley   +1 more source

Coronary artery calcium on lung cancer screening-CT: An opportunity to optimize cardiovascular disease risk reduction

International Journal of Cardiology: Heart & Vasculature
Background: In lung cancer screening trials, mortality from cardiovascular disease occurs at similar rates to lung cancer deaths. Survival following lung cancer screening could be optimized if atherosclerosis prevention was targeted.
Bethlehem Mengesha, Keren Mbondo Kasuku, Toby David Small, Marcella Cabral Caires, Habibat Garuba, Angeline Law, Christopher Johnson, David Ian Paterson, Carole Dennie, Elena Pena, Benjamin JW Chow, Gary R Small   +11 more
doaj   +1 more source