Inorganic Nanomaterials Meet the Immune System: An Intricate Balance
Metal nanomaterials influence the immune responses, such as cytokine production and T‐cell activity. Unintended immune modulation can have significant consequences while its fine‐tuning may transform the oncology care. Within this review, a critical analysis is offered regarding the nano/immune‐interaction and suggests the future research directions to
Gloria Pizzoli+3 more
wiley +1 more source
The effects of clinically-derived parametric data uncertainty in patient-specific coronary simulations with deformable walls [PDF]
Cardiovascular simulations are increasingly used for non-invasive diagnosis of cardiovascular disease, to guide treatment decisions, and in the design of medical devices. Quantitative assessment of the variability of simulation outputs due to input uncertainty is a key step toward further integration of cardiovascular simulations in the clinical ...
arxiv
Implantation of paclitaxel-eluting stents in saphenous vein grafts: clinical and angiographic follow-up results from a multicentre study. [PDF]
Objective: To define the clinical and angiographic follow-up results after implantation of paclitaxel-eluting stents (PESs) in stenotic saphenous vein grafts (SVGs). Design: Prospective multicentre study. Comparison with a control group.
Blindt, Ruediger+5 more
core +2 more sources
An RBC membrane camouflaged, cell‐penetrating peptides R8‐based drug delivery system is constructed to achieve a synergistic combination of natural compounds triptolide (TP) and celastrol (Cel), inducing tumor cell apoptosis, reducing tumor metastasis invasion and triggering autophagy disorder in breast cancer and liver cancer.
Qian Cheng+6 more
wiley +1 more source
Deep learning based detection of collateral circulation in coronary angiographies [PDF]
Coronary artery disease (CAD) is the dominant cause of death and hospitalization across the globe. Atherosclerosis, an inflammatory condition that gradually narrows arteries and has potentially fatal effects, is the most frequent cause of CAD. Nonetheless, the circulation regularly adapts in the presence of atherosclerosis, through the formation of ...
arxiv +1 more source
Detection and localization of Coronary Arterial Lesion with the Aid of Impedance Cardiography [PDF]
In recent years, coronary artery disease is escalating and is likely to assume an epidemic proportion by 2030. Currently the reliable methods for detection of coronary arterial lesions are either conventional coronary angiogram (CAG) or MDCT (Multiple Detector Computed Tomography) coronary angiogram.
arxiv
ACE-inhibition prevents postischemic coronary leukocyte adhesion and leukocyte-dependent reperfusion injury [PDF]
Objective: Polymorphonuclear leukocytes (PMN), retained in the microvascular bed, can contribute to postischemic myocardial reperfusion injury. Since a beneficial effect of ACE-inhibition on reperfusion injury has been reported, we investigated the ...
Becker, Bernhard F.+6 more
core +1 more source
Historical Aspects and Relevance of the Human Coronary Collateral Circulation
In 1669, anastomoses between the right and left coronary artery were first documented by Richard Lower of Amsterdam. Using post-mortem imaging, a debate followed on the existence of structural inter-coronary anastomoses, which was not resolved before the
C. Seiler, P. Meier
semanticscholar +1 more source
Albumin Corona Overturns Long‐Acting Behaviors of Myristic Acid‐Conjugated Quetiapine Nanosuspension
Albumin corona alters surface properties and enhances colloidal stability by overturning pH responsiveness and nano‐aggregation behaviors of long‐acting myristic acid‐conjugated quetiapine nanosuspensions (QMN), resulting in accelerated in vitro and in vivo drug release.
Hy Dinh Nguyen+2 more
wiley +1 more source