Results 141 to 150 of about 10,214,758 (341)

Restoration of SIRT3 Expression in Aged Mice Alleviates UUO‐Induced Renal Fibrosis by Reducing GSK‐3β Hyperacetylation

Advanced Science, EarlyView.
SIRT3 expression is significantly downregulated in the aged kidney, rendering the kidney more vulnerable to fibrotic changes in obstructive nephropathy. By promoting GSK‐3β deacetylation, SIRT3 indirectly inhibits Wnt/β‐catenin signaling, thereby suppressing renal fibrosis.
Jing Wang, Xiang Ren, Huan Lu, Zihao Guo, Xing Li, Yiqun Tian, Yisheng Yin, Zhenliang Qin, Kun Yun, Minglong Wu, Gang Chen, Xiaoyong Zeng   +11 more
wiley   +1 more source

Prognostic value of serum glycated albumin in acute coronary syndrome patients without standard modifiable cardiovascular risk factors

Diabetology & Metabolic Syndrome
Background Glycated albumin (GA) has been demonstrated to be associated with adverse outcomes in patients with acute coronary syndrome (ACS). However, as a specific subgroup of ACS, a significant proportion of patients with ACS without standard ...
Xiaoming Zhang, Yu Du, Qianyun Guo, Xiaoteng Ma, Dongmei Shi, Yujie Zhou   +5 more
doaj   +1 more source

Fractional flow reserve-guided PCI versus medical therapy in stable coronary disease.

New England Journal of Medicine, 2012
B. de Bruyne, N. Pijls, B. Kalesan, E. Barbato, P. Tonino, Z. Piróth, N. Jagic, S. Möbius‐Winkler, G. Rioufol, N. Witt, P. Kala, P. MacCarthy, Thomas Engström, K. Oldroyd, K. Mavromatis, G. Manoharan, P. Verlee, O. Frøbert, N. Curzen, Jane B Johnson, P. Jüni, W. Fearon   +21 more
semanticscholar   +1 more source

Tumor Extracellular Vesicles Aggravate Mitochondrial Damage in Myocardial Ischemia/Reperfusion Injury

Advanced Science, EarlyView.
This study reveals a novel mechanistic connection between cancer and ischemia/reperfusion (I/R)‐induced cardiac injury. The meta‐analysis demonstrates significantly higher incidence ratios of both all‐cause mortality and cardiovascular mortality in cancer patients undergoing percutaneous coronary intervention (PCI) compared to non‐cancer patients.
Zhongting Mei, Qian Liu, Guoxin Liu, Manjie Zhang, Jiaxin Fang, Xuting He, Xueqi He, Zhengwei Qin, Ronghua Liu, Chuang Liu, Hongyu Ji, Yuechao Dong, Ye Yuan, Baofeng Yang, Weijie Du   +14 more
wiley   +1 more source

Cancer and coronary artery disease among seventh-day adventists

, 1959
Ernest L. Wynder, Frank R. Lemon, Irwin J. Bross   +2 more
openalex   +1 more source

Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. Heart and Estrogen/progestin Replacement Study (HERS) Research Group.

Journal of the American Medical Association (JAMA), 1998
S. Hulley, D. Grady, T. Bush, C. Furberg, D. Herrington, B. Riggs, E. Vittinghoff   +6 more
semanticscholar   +1 more source

Lactate‐Activated GPR132‐Src Signal Induces Macrophage Senescence and Aggravates Atherosclerosis Under Diabetes

Advanced Science, EarlyView.
Elevated lactate in diabetes activates the GPR132‐Src pathway in macrophages, inducing macrophage senescence and further enhancing foam cell formation. This mechanism exacerbates atherosclerotic progression. Abstract Diabetes is widely acknowledged as a significant risk factor for atherosclerosis, facilitating plaque formation through various ...
Xiaofeng Ge, Shuying Wang, Zhaokai Li, Jing Yu, Binbin Liu, Ruiying Wang, Shichen Bu, Nawsher wan, Yan Wang, Cuilian Dai, Yijun Lin   +10 more
wiley   +1 more source

Platelets and coronary disease [PDF]

BMJ, 1985
openaire   +3 more sources

Ligilactobacillus Murinus and Lactobacillus Johnsonii Suppress Macrophage Pyroptosis in Atherosclerosis through Butyrate‐GPR109A‐GSDMD Axis

Advanced Science, EarlyView.
Oral aspirin administration induces intestinal expansion of Lactobacillus murinus and Lactobacillus johnsonii, which suppresses the progression of atherosclerosis. This microbial expansion significantly enhances butyrate production by providing lactate as a metabolic substrate, thereby fostering the growth of butyrate‐producing bacteria. Butyrate plays
Rui Hua, Ning Ding, Yiming Hua, Xiaoke Wang, Yu Xu, Xiangrui Qiao, Xue Shi, Ting Bai, Ying Xiong, Xiaozhen Zhuo, Chong Fan, Juan Zhou, Yue Wu, Junhui Liu, Zuyi Yuan, Ting Li   +15 more
wiley   +1 more source

THE RELATION BETWEEN MYOCARDIAL LESIONS AND CORONARY ARTERY DISEASE II. A SELECTED GROUP OF PATIENTS WITH MASSIVE CARDIAC NECROSIS OR SCARRING [PDF]

, 1963
J.R.A. Mitchell, C. J. Schwartz
openalex   +1 more source