Results 211 to 220 of about 1,382,114 (327)

Leucine‐Dependent SLC7A5–PGAM5 Interaction Promotes Advanced Atherosclerosis Through Hindering Mitochondrial Function of Macrophages

Advanced Science, EarlyView.
Higher plasma leucine is associated with increased risk of new‐onset myocardial infarction. Leucine deprivation alleviates advanced atherosclerosis in mice. Tumor‐induced leucine deprivation reprograms macrophage metabolism and increases CD5Lhi macrophages in mouse plaques. Mechanistically, leucine deficiency reduced SLC7A5‐PGAM5 binding in macrophages,
Shan Zhong, Xueyu Wang, Qingsong Li, Siqi Wang, Bin Sun, Wenjun Ni, Gengyu Zhou, Fan Wang, Xianwei Xie, Cheng Jin, Gang Xu, Peng Zhao, Xiang Peng, Feiyuan Han, Xiangwen Xi, Yidan Wang, Juan Xu, Yue Wang, Xia Gu, Shuo Li, Jian Zhang, Shuijie Li, Jinwei Tian   +22 more
wiley   +1 more source

Can Gene Expression Differentiate Patients With Heart Failure due to Coronary Heart Disease From Patients With Coronary Disease Without Heart Failure? [PDF]

J Cell Mol Med
Dąbek J, Głogowska-Ligus J, Piechota M.   +2 more
europepmc   +1 more source

Microgel‐Based Hierarchical Porous Hydrogel Patch with Adhesion and Resilience for Myocardial Infarction

Advanced Science, EarlyView.
This study develops a hierarchically porous hydrogel patch strategy (HPMP), based on gas‐shearing microfluidics and an aqueous two‐phase system to fabricate porous microgels as microgel‐based bioinks. The porous microgels with controllable porous structure exhibit excellent cellular behavior.
Ziyang Liu, Leyan Xuan, Yingying Hou, Ting Xie, Jieting Li, Junjie Cai, Siyu Zhang, Yingling Miao, Ning Hou, Gen He, Maobin Xie, Xiyong Yu, Mingen Xu, Guosheng Tang   +13 more
wiley   +1 more source

Sex Differences in Psychosocial Factors and Angina in Patients With Chronic Coronary Disease. [PDF]

J Am Heart Assoc
Hausvater A, Anthopolos R, Seltzer A, Spruill TM, Spertus JA, Peteiro J, Lopez-Sendon JL, Čelutkienė J, Demchenko EA, Kedev S, Beleslin BD, Sidhu MS, Grodzinsky A, Fleg JL, Maron DJ, Hochman JS, Reynolds HR, CIAO‐ISCHEMIA Research Group.   +17 more
europepmc   +1 more source

CD147/Basigin: From Integrative Molecular Hub to Translational Therapeutic Target

Advanced Science, EarlyView.
This review conceptualizes CD147 as a fundamental “Energy‐Structure Coupler,” physically bridging metabolic flux (via MCTs) with morphogenetic plasticity (via integrins/MMPs) to drive cancer, infection, and autoimmunity. Addressing the “specificity paradox” that limits current translation, the authors chart a strategic roadmap—spanning logic‐gated ...
Xiang‐Min Yang, Huijie Bian, Zhi‐Nan Chen   +2 more
wiley   +1 more source

Risk Factors Associated With Coronary Disease in Saudi Arabia: A Comprehensive Review. [PDF]

Cureus
Alsuheimy AA, Aljuaid AB, Albalawi FN, Hassounah E, Modahi F, Alkhurayji K.   +5 more
europepmc   +1 more source

Hemoglobin A _1c Is Associated With Increased Risk of Incident Coronary Heart Disease Among Apparently Healthy, Nondiabetic Men and Women [PDF]

, 2013
Jennifer K. Pai, Leah E. Cahill, Frank B. Hu, Kathryn M. Rexrode, JoAnn E. Manson, Eric B. Rimm   +5 more
openalex   +1 more source

Chaperone‐Mediated Autophagic Degradation of USP9X in Macrophages Exacerbates Postmyocardial Infarction Inflammation and Cardiac Dysfunction

Advanced Science, EarlyView.
This study demonstrates that inflammatory stimuli induce the acetylation‐triggered, chaperone‐mediated autophagic degradation of ubiquitin‐specific peptidase 9 X‐linked (USP9X) in macrophages. USP9X acts as a macrophage “inflammation switch” after myocardial infarction (MI). USP9X loss destabilizes tumor necrosis factor receptor‐associated factor (TRAF)
Biqing Wang, Xiangheng Cai, Mengqi Li, Xue Liu, Junhui Xue, Ye Liu, Ding Ai, Xinyang Hu   +7 more
wiley   +1 more source

Ectopic adipose tissue in subsistence populations with minimal coronary disease, large left atria, and very low rates of atrial fibrillation. [PDF]

Am J Prev Cardiol
Thompson RC, Trumble BC, Cummings DK, Neunuebel AD, Hooper PL, Wann S, Allam AH, Neunuebel F, Gans BD, King SI, Seabright E, Finch CE, Gatz M, Buetow K, Miyamoto MI, Lombardi GP, Sutherland ML, Sutherland JD, Ward C, Lee MJ, Mahadev A, Rodriguez DE, Michalik DE, Rowan CJ, Cao T, Stieglitz J, Quick CM, Thomas GS, Narula J, Dey D, Gurven M, Kaplan H.   +31 more
europepmc   +1 more source

Serum uric acid and long-term mortality from stroke, coronary heart disease and all causes [PDF]

, 2006
Yariv Gerber, David Tanné, Jack H. Medalie, Uri Goldbourt   +3 more
openalex   +1 more source