Results 71 to 80 of about 455,893 (183)

12-Lipoxygenase in porcine coronary microcirculation: implications for coronary vasoregulation

, 2001
Noncyclooxygenase metabolites of arachidonic acid (AA) have been proposed to mediate endothelium-dependent vasodilation in the coronary microcirculation.
Martin H. Zink, Christine L. Oltman, Prasad V. G. Katakam, Terry L. Kaduce, Tong Lu, Neal L. Weintraub, Kevin C. Dellsperger, Hon-Chi Lee, Arthur A. Spector, Paul R. Myers   +9 more
core   +1 more source

Cardiomyocyte Membrane‐Camouflaged Spinach Nano‐Thylakoids Enhance Myocardial Energy Metabolism and Ameliorate Heart Failure

Small, EarlyView.
Schematic illustration of the construction of MM‐NTU, its cardiac‐targeting behavior, and its light‐activated therapeutic mechanism. Thylakoids isolated from spinach chloroplasts were processed into nano‐thylakoid units (NTU) and further camouflaged with cardiomyocyte membranes to generate MM‐NTU.
Haohui Fan, Bei Song, Chengyun Liu, Peiyu Zhong, Quan Zhou, Xiaofang Zhao, Guangyu Gao, Xinyue Zhang, Xueke Guang, Tianci Yao, Ting Liu, Hao Zhang, Xinqi Diao, Weilin Lu   +13 more
wiley   +1 more source

Renal oxygenation, function and histopathology in an ovine model of heart failure undergoing cardiopulmonary bypass with 48 hours of recovery: a prospective, observational study*

Anaesthesia, EarlyView.
Summary Introduction Acute kidney injury is common after cardiac surgery requiring cardiopulmonary bypass, yet preventive strategies are limited. Progress has been hindered by a lack of clinically relevant experimental models incorporating pre‐existing heart disease.
Anton L. Trask‐Marino, Bruno Marino, Taku Furukawa, Lachlan F. Miles, Jai Raman, Andrew D. Cochrane, Peter R. McCall, Terase F. Lancefield, Roger G. Evans, Ian E. Birchall, Alemayehu H. Jufar, Ashenafi Betrie, Lars I.P. Snel, Munenori Kusunoki, Sally G. Hood, Linda Cornthwaite, Bruce Treagus, Connie Pei Chen Ow, Lindsea C. Booth, Clive N. May, Yugeesh R. Lankadeva   +20 more
wiley   +1 more source

Coronary collateral function in the transplanted heart: propensity score matching with coronary artery disease

, 2011
The function of the coronary collateral circulation in heart transplant patients has not been investigated in a controlled fashion. Since it partly belongs to the microcirculation, which is affected by transplant vasculopathy, the hypothesis was tested ...
Seiler, C., de Marchi, S.F., Vogel, R., S. Gloekler, Eshtehardi, P., Vogel, Rolf, Mohacsi, Paul, Gloekler, S., Mohacsi, P., Meier, Pascal, P. Meier, Cook, Stéphane, T. Rutz, R. Vogel, Rutz, Tobias, Gloekler, Steffen, Rutz, T., Eshtehardi, Parham, P. Mohacsi, S. Cook, S. F. de Marchi, T. Traupe, Cook, S., de Marchi, Stefano F., Traupe, T., Seiler, Christian, Traupe, Tobias, P. Eshtehardi, C. Seiler, Meier, P., Seiler C, Rutz T, Vogel R, Meier P, Mohacsi P, Traupe T, Gloekler S, Glökler, Steffen, Eshtehardi P, de Marchi SF, De Marchi, Stefano, Cook S   +41 more
core   +1 more source

Coronary microvascular dysfunction: pathophysiology, diagnosis, and therapeutic strategies across cardiovascular diseases

EXCLI Journal : Experimental and Clinical Sciences
Ischemic heart disease (IHD) is a leading cause of morbidity and mortality worldwide, presenting with acute and chronic coronary syndromes. Although coronary atherosclerosis is a major cause of IHD, many patients with angina or myocardial ischemia do ...
Vincenzo Scarica, Riccardo Rinaldi, Francesco Maria Animati, Matteo Manzato, Rocco Antonio Montone   +4 more
doaj   +1 more source

The relationship of microcirculation parameters of the bulbar conjunctiva and coronary angiography in patients with coronary artery disease

Российский кардиологический журнал, 2019
Aim. To identify the associations between microcirculation parameters obtained using the method of bulbar conjunctiva videobiomicroscopy and coronary angiography in patients with acute coronary syndrome (ACS).Material and methods. Fifty six patients with
N. V. Korneeva, B. Z. Syrotin, N. V. Bondar, V. Ya. Rudman   +3 more
doaj   +1 more source

Photobiomodulation as a contemporary antioxidant intervention in myocardial infarction

Experimental Physiology, EarlyView.
Abstract Myocardial infarction (MI) triggers a complex cascade of structural and functional alterations that frequently culminate in adverse cardiac remodelling and heart failure. Central to this process is the excessive production of reactive oxygen species (ROS), which disrupt mitochondrial function, impair calcium handling, and activate pro ...
Gabriel Matheus Da Silva Batista, Ighor Luiz Azevedo Teixeira, Ednei Luiz Antonio, Andrey Jorge Serra   +3 more
wiley   +1 more source

Prolonged leukocyte transit time in coronary microcirculation of endotoxemic pigs

, 1995
We quantified the timing and extent of leukocyte retention by the coronary microcirculation in a pig model of hyperdynamic sepsis in three ways. First, the transmyocardial leukocyte gradient was determined as coronary blood flow (calibrated ultrasonic ...
J. C. Hogg, M. F. Allard, C. M. Goddard, M. J. Herbertson, K. R. Walley   +4 more
core   +1 more source

The effect of repeated hot water immersion on microvascular function, glycaemic control and inflammation in White European and South Asian males

Experimental Physiology, EarlyView.
Abstract Individuals of South Asian (SA) descent display a higher risk for cardiovascular disease and type 2 diabetes mellitus than their White European (WE) counterparts. Heat therapy, such as hot water immersion (HWI), can improve microvascular function and glycaemic control, although effects across racial groups are unknown.
David Bellini, Alex Lloyd, Christof A. Leicht, Stephen J. Bailey, Lewis J. James, Matthew J. Maley   +5 more
wiley   +1 more source

Remote ischemic conditioning improves coronary microcirculation in healthy subjects and patients with heart failure

, 2014
Yasushi Kono,1 Shota Fukuda,1 Akihisa Hanatani,2 Koki Nakanishi,2 Kenichiro Otsuka,2 Haruyuki Taguchi,1 Kenei Shimada2 1Department of Medicine, Osaka Ekisaikai Hospital, Osaka, Japan; 2Department of Internal Medicine and Cardiology, Osaka City University
Taguchi H, Kono Y, Hanatani A, Nakanishi K, Otsuka K, Fukuda S, Shimada K   +6 more
core