Results 201 to 210 of about 128,004 (314)

Inhibition of adenosine kinase alleviates hypertrophic cardiomyopathy by ameliorating coronary microvascular dysfunction. [PDF]

ESC Heart Fail
Wan F, Ma B, Han Z, Zheng Y, Lu M, Chen J, Wang J, Song L.   +7 more
europepmc   +1 more source

Born early, age fast: Consequences of premature birth on chronic disease and accelerated ageing

The Journal of Physiology, EarlyView.
Abstract figure legend ELGANs are exposed to several postnatal pro‐oxidant stressors, including ambient and supplemental oxygen, mechanical ventilation, infections, hyperalimentation, excessive glucocorticoids and intermittent hypoxia. Since endogenous antioxidant defences are underdeveloped, this imbalance promotes oxidative stress and inflammation ...
Estelle B. Gauda, Julijana Ivanovska, Dwayne Mascarenhas, Jeffrey Antwi, Atefeh Mohammadi, Bonny Jasani   +5 more
wiley   +1 more source

Coronary Microvascular Dysfunction in Cardiomyopathies: Insights on Clinical and Prognostic Roles. [PDF]

Rev Cardiovasc Med
Giacobbe F, Meynet P, Balducci M, Capoccia S, Cimino RA, Morena A, Dalu A, D'Ascenzo F, De Filippo O, Novarese F, Bruno F, Raineri C, Conrotto F, Sakalidis A, Omedé P, Giannino G, Angelini F, Bocchino PP, Dusi V, Porto I, De Ferrari GM.   +20 more
europepmc   +1 more source

Energetic microdomains and the vascular control of neuronal and muscle excitability: Toward a unified model

The Journal of Physiology, EarlyView.
Abstract figure legend The capillary–mitochondria–ion channel (CMIC) axis scales structural resources to match functional workload. (Left) In settings of restricted energetic capacity (e.g. cortical neurons), sparse capillary networks and modest mitochondrial pools set a lower energetic ceiling, sufficient to support phasic, low‐workload excitability. (
L. Fernando Santana, Scott Earley
wiley   +1 more source

Coronary Microvascular Dysfunction and Lipid Molecules: Pathophysiological Mechanisms, Clinical Assessment, and Therapeutic Implications. [PDF]

J Pers Med
Hafez A, Farina JM, Awad K, Pietri MP, Scalia IG, Sheashaa H, Abdelfattah FE, Razaghi M, Ahmed S, Ibrahim R, Simper D, Lester SJ, Tamarappoo B, Ayoub C, Arsanjani R.   +14 more
europepmc   +1 more source

Photobiomodulation restores blood–brain barrier integrity after hypoxia via endothelial von Willebrand factor modulation in a humanised tricellular transwell model

The Journal of Physiology, EarlyView.
Abstract figure legend Photobiomodulation restores blood–brain barrier (BBB) integrity following hypoxic stress. A multicellular human BBB model comprising brain microvascular endothelial cells, astrocytes and pericytes was established in a transwell system and subjected to acute hypoxia.
Mirriam Domocos, Denis E. Bragin, Nagesh C. Shanbhag, Luise Schlotterose, Mootaz M. Salman   +4 more
wiley   +1 more source

Insulin resistance and coronary microvascular dysfunction: a complex interplay. [PDF]

Cardiovasc Diabetol
Magistri M, Portolan L, Trevisanello A, Tosi F, Locatelli A, Piana S, Rubinelli M, Molinaroli E, Mantovani A, Ribichini F, Kunadian V, Bonadonna R, Scarsini R.   +12 more
europepmc   +1 more source

The Shifting Sands of Coronary Microvascular Dysfunction [PDF]

Circulation, 2019
William F, Fearon, Bernard, De Bruyne
openaire   +2 more sources

Tissue microvascular flow and oxygenation in critically ill patients

, 2012
PhDThe use of fluid resuscitation and vasoactive agents to optimise global haemodynamics has been demonstrated to improve outcomes in patients undergoing major surgery and in early sepsis.
Jhanji, Shaman
core  

A microstructurally motivated framework to study autoregulation in the coronary circulation

The Journal of Physiology, EarlyView.
Abstract figure legend A microstructurally motivated framework was constructed to simulate coronary autoregulation in symmetrically bifurcating trees at three myocardial depths: subepicardial (subepi), midwall and subendocardial (subendo). Wall mechanics of individual vessels are governed by a constrained‐mixture model, incorporating elastin, collagen ...
Matthew J. Eden, Hamidreza Gharahi, Victoria E. Sturgess, Domingo E. Uceda, Gregory M. Dick, Seungik Baek, Daniel A. Beard, Johnathan D. Tune, C. Alberto Figueroa   +8 more
wiley   +1 more source