Results 101 to 110 of about 494,023 (345)

Generation of an Induced Pluripotent Stem Cell‐Derived Alveolar Type II In Vitro Model to Study Influenza A Virus Infection and Drug Treatments

Advanced Healthcare Materials, EarlyView.
Patient‐specific induced pluripotent stem cells (iPSCs) can be differentiated into alveolar type II cells (iAT2s), expanded as 3D alveolospheres, and grown at physiologically relevant air–liquid interface (ALI). This study shows for the first time the infectability of iAT2s by the influenza A virus (IAV) and proves their responsiveness to the well ...
Lena Gauthier, Hristina Koceva, Yann Bachelot, Rosanne W. Koutstaal, Puck B. van Kasteren, Marc Thilo Figge, Christian Eggeling, Alexander Sandy Mosig   +7 more
wiley   +1 more source

Metabolic alterations upon SARS-CoV-2 infection and potential therapeutic targets against coronavirus infection [PDF]

, 2023
Peiran Chen, Mandi Wu, Yaqing He, Bing‐Hua Jiang, Ming‐Liang He   +4 more
openalex   +1 more source

Identification of individuals with gonorrhoea within sexual networks: a population-based study.

, 2006
BACKGROUND: Molecular typing of Neisseria gonorrhoeae and contact tracing provide a combined approach for analysis of sexual networks in metropolitan areas, although there are some difficulties in application.
Bishop, Cynthia J, Choudhury, Bhudipa, Fenton, Kevin A, Ghani, Azra C, Ison, Catherine A, Risley, Claire L, Spratt, Brian G, Ward, Helen   +7 more
core   +1 more source

Membrane Fusion‐Inspired Nanomaterials: Emerging Strategies for Infectious Disease and Cancer Diagnostics

Advanced Healthcare Materials, EarlyView.
Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee, Khulan Nyamzaya, Jueun Han, Yejin Song, Jihee Lee, Jung Hyun Jo, Seungmin Bang, Eun‐Kyung Lim, Seungjoo Haam, Eunjung Kim   +9 more
wiley   +1 more source

Cesarean Section in a Pregnant Woman with COVID-19: First Case in Portugal

Acta Médica Portuguesa, 2020
We report the first cesarean delivery in a woman with COVID-19 in a level III hospital in Portugal. It refers to a healthy woman with a term pregnancy that tested positive for COVID-19 on the day of labor induction. Given a Bishop score < 4 and the prior
Joana Lyra, Rita Valente, Marta Rosário, Mariana Guimarães   +3 more
doaj   +1 more source

Multivalent Protein Nanorings for Broad and Potent SARS‐CoV‐2 Neutralization

Advanced Healthcare Materials, EarlyView.
A protein‐only, modular multivalent nanoscaffold displaying 20 anchor points, decorated with two different binders (10 of each), targeting the SARS‐CoV‐2 receptor‐binding domain is presented. The construct self‐assembles into stable, biocompatible, homogeneous nanoparticles, exhibit synergistic binding with fM IC50 values. It also detects spike at 9 ng 
Molood Behbahanipour, Carla Goldin, Cecilia Arahi Prato, Ana Luz Paletta, Oriol Bárcenas, Susanna Navarro, Jordi Pujols, Daniel H. Murgida, María Virginia Tribulatti, Sebastián Esperante, Damian Alvarez‐Paggi, Salvador Ventura   +11 more
wiley   +1 more source

Therapeutic Potential of Bioactive Compounds from Edible Mushrooms to Attenuate SARS-CoV-2 Infection and Some Complications of Coronavirus Disease (COVID-19) [PDF]

, 2023
Paran Baruah, Aparup Patra, Sagar Barge, Mojibur R. Khan, Ashis K. Mukherjee   +4 more
openalex   +1 more source

A human coronavirus responsible for the common cold massively kills dendritic cells but not monocytes [PDF]

, 2012
Copyright @ 2012, American Society for Microbiology.Human coronaviruses are associated with upper respiratory tract infections that occasionally spread to the lungs and other organs.
A. Vabret, Abt, Arbour, Arbour, B. Nal, Bonavia, Caignard, Caignard, Callendret, Callow, Caux, Chapuis, Collins, de Swart, de Witte, Desforges, Desforges, Engelmayer, Esposito, F. Tangy, Ferlazzo, Gagneur, Geijtenbeek, Glew, H. Law, Hahm, Hamdorf, Herbst, Hoarau, J. Millet, Kramer, Kärber, Law, Legge, M. L. Albert, M. Mesel-Lemoine, MacDonald, Mahanty, Movassagh, Muller, N. Escriou, Nogueira, O'Doherty, Olweus, P.-O. Vidalain, Pacanowski, Piqueras, Rosenzwajg, Sallusto, Servet-Delprat, Servet-Delprat, Servet-Delprat, Sizun, Spearman, Spiegel, Thitithanyanont, Thornberry, V. Lorin, Vabret, Wang, Yang, Yeager   +61 more
core   +3 more sources

Evaluating the Antiviral Efficacy of Encapsulated PKC Inhibitor BIM‐I against influenza A Virus Infection

Advanced Healthcare Materials, EarlyView.
This study explores nanoparticle delivery of the protein kinase C inhibitor bisindolylmaleimide‐I (BIM‐I) to combat influenza A virus infections. Encapsulation in biodegradable PLGA nanoparticles improved safety while maintaining the compound's strong antiviral activity.
Laura Klement, Jana Ismail, Josefine Schroeder, Amod Godbole, Johanna Schreiber, Christine Weber, Zoltan Cseresnyes, Marc T. Figge, Bettina Löffler, Ulrich S. Schubert, Stephanie Schubert, Christina Ehrhardt, Carsten Hoffmann   +12 more
wiley   +1 more source

Effects of severe acute respiratory syndrome coronavirus 2 infection on obstetric outcomes: Results from a prospective cohort in the Netherlands [PDF]

, 2022
Frederieke Gigase, Myrthe G. B. M. Boekhorst, Anna‐Sophie Rommel, Siobhan M. Dolan, Victor J.M. Pop, Veerle Bergink, Lot D. de Witte   +6 more
openalex   +1 more source