Results 91 to 100 of about 44,957 (175)

Molecular mechanisms of severe acute respiratory syndrome (SARS)

, 2005
Severe acute respiratory syndrome (SARS) is a new infectious disease caused by a novel coronavirus that leads to deleterious pulmonary pathological features.
David A Groneberg, Groneberg, David A., Peter Zabel, Groneberg, Jan David Alexander, Zabel, Peter, Rolf Hilgenfeld, Hilgenfeld, Rolf   +6 more
core   +1 more source

Repurposed Medicines for Viruses With Epidemic or Pandemic Potential: A Horizon Scan

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT Viruses such as Ebola, Marburg, influenza, mpox, MERS‐CoV, SARS‐CoV, and SARS‐CoV‐2 may be considered pathogens of epidemic or pandemic concern. Developing novel antiviral medicines can be time‐consuming and resource intensive. Repurposing existing medicines with known or potential antiviral activity offers a faster, cost‐effective strategy to
Sola Akinbolade, Rhiannon Potter, Alex Inskip, Jane Nesworthy, Kirsti Brock, Gill Norman   +5 more
wiley   +1 more source

Structural basis for RNA replication by the SARS-CoV-2 polymerase

, 2020
Cryo-EM structures of the SARS-CoV-2 RNA polymerase in complexes with RNA, before and after RNA translocation, reveals structural rearrangements that the RNA-dependent RNA polymerase (RdRp) nsp12 and its co-factors (nsp7 and nsp8) undergo to accommodate ...
Wang, Quan, Gao, Hailong, Lou, Zhiyong, Yang, Xiaobao, Yan, Liming, Yang, Xiuna, Xu, Wenqing, Rao, Zihe, Wang, Haofeng, Ge, Ji, Sun, Qianqian, Zhu, Yan, Liu, Qiaojie, Jiang, Biao, Mu, An, Yang, Haitao, Gao, Yan, Gong, Peng, Guddat, Luke W., Ji, Wenxin, Liu, Fengjiang, Liu, Zhijie, Zhu, Chen, Fang, Xiang, Huang, Yucen, Wu, Jiqin   +25 more
core   +1 more source

Manufacturing and clinical applications of non‐CAR‐T immune effector cells

Transfusion, EarlyView.
Thane Kubik, Theodros Mamo, David H. McKenna   +2 more
wiley   +1 more source

Tautomerism‐Governed Two‐Proton‐Coupled Electron Transfer in the Oxidation of a Molnupiravir by Electrogenerated Superoxide Radical Anion in N,N‐Dimethylformamide

ChemistrySelect, Volume 11, Issue 21, 4 June 2026.
Tautomerization‐assisted oxidation of molnupiravir by superoxide (O2•−) in aprotic DMF. The thermodynamically favored oxime tautomer of the N4‐hydroxycytosine moiety forms a prereactive complex (PRC) with O2•− through hydrogen‐bonding interactions.
Tatsushi Nakayama, Kaisei Hara
wiley   +1 more source

Successful in vitro propagation of feline coronavirus from clinically diagnosed feline infectious peritonitis cases using Vero cells: A potential model for future research

Veterinary Record Open, Volume 13, Issue 1, June 2026.
Abstract Background Feline coronavirus (FCoV) causes inapparent to progressive fatal feline infectious peritonitis (FIP) in domestic and wild cats, which affects multiple‐organ systems. Methods We investigated three clinically sick cats using different laboratory and molecular tests to diagnose and confirm FCoV and propagate the virus in Vero cell ...
Eaftekhar Ahmed Rana, Mahfuza Akther, Susan Beetson, Subir Sarker, Gabriele Rossi, Jasim M. Uddin   +5 more
wiley   +1 more source

Relationships Between European Wildcats and Domestic Cats in an Area of Sympatry: Exploring Key Conservation Questions on Hybridization and Disease Transmission

Animal Conservation, Volume 29, Issue 3, Page 321-333, June 2026.
We have found evidence of behavioural barriers for both hybridization and disease transmission between European wildcats and domestic cats. This includes hierarchical interspecies exclusion enforced by wildcats, as well as sexual selection exerted by wildcat females.
Jose María Gil‐Sánchez, Elena Bertos, Mariola Sánchez‐Cerdá, Emilio Virgós, Marcos Moleón   +4 more
wiley   +1 more source

Functional analysis of the orthobunyavirus nucleocapsid (N) protein

, 2008
Bunyamwera virus (BUNV) is the prototype of the family Bunyaviridae. It has a tripartite genome consisting of negative sense RNA segments called large (L), medium (M) and small (S). The S segment encodes the nucleocapsid protein (N) of 233 amino acids.
Eifan, Saleh A.
core  

Molecular characterization and detection of infectious bronchitis virus [PDF]

, 2012
This thesis deals with the molecular characterization and detection of infectious bronchitis virus (IBV), an important pathogen that causes heavy losses in the poultry populations worldwide.
Abro, Shahid Hussain
core  

Favipiravir strikes the SARS-CoV-2 at its Achilles heel, the RNA polymerase

, 2020
The ongoing Corona Virus Disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has emphasized the urgent need for antiviral therapeutics.
Piorkowski, G., Canard, B., Huchting, J., Selisko, B., Touret, F., Shannon, A., Le, Ntt, Fattorini, V., Meier, C, Peersen, O., Coutard, B., Ferron, F., Decroly, Etienne   +12 more
core   +1 more source