Results 71 to 80 of about 77,457 (174)

The human enteric coronaviruses [PDF]

Postgraduate Medical Journal, 1979
Summary A coronarirus was seen in the faeces from 15 (4·2%) of 355 adults with diarrhoea and from 5 (5·2%) of 96 adults without diarrhoea. Similar particles were seen in the faeces from 5 (2·2%) of 227 children aged 1–14 years with gastroenteritis, but in none of those from 230 infants under one year of age with gastroenteritis.
S K, Clarke, E O, Caul, S I, Egglestone
openaire   +2 more sources

Visible Photosensitizing Disinfectant Spray for Combating Multidrug‐Resistant Candidozyma Auris in Healthcare Settings

Exploration, EarlyView.
We designed and synthesized a dual‐type AIE photosensitizer (named TB) spray, containing a cationic quaternary ammonium unit and a glycosyl‐targeted boronic acid moiety, characterized for the elimination of biofilm infections of Candidozyma auris (C. auris) on high‐touch surfaces.
Xiaoyu Xu, Ming‐Yu Wu, Baoping Li, Jie Li, Siyu Chen, Luojia Chen, Donghu Yu, Liupiaopiao Yang, Ziyu Hong, Huaqin Pan, Wei Xiang, Shun Feng, Jong Seung Kim, Lianrong Wang, Zhiqiang Li, Shi Chen, Meijia Gu   +16 more
wiley   +1 more source

The evolutionary landscape and serotypic dynamics of avian infectious bronchitis virus from spike protein

iMetaOmics, EarlyView.
This study integrates two decades of surveillance with genomic and structural analyses to decipher how spike protein glycosylation haplotypes drive avian coronavirus evolution. We uncover how specific glycosylation patterns associate with receptor‐binding affinity, shape global transmission dynamics, and correlate with clinical outcomes.
Hao Zhang, Zongxi Han, Chuangchao Zou, Yihui Huang, Shiping Sun, Ouyang Peng, Usama Ashraf, Qiuping Xu, Yao Ge, Qixiang Kang, Xiuli Ma, Xinheng Zhang, Ye Zhao, Xin Yang, Hongning Wang, Guozhong Zhang, Qingmei Xie, Mang Shi, Yongsen Ruan, Min Liao, Shengwang Liu, Yongchang Cao   +21 more
wiley   +1 more source

Akkermansia muciniphila enhances chicken resistance to infectious bronchitis virus by boosting GABA synthesis and suppressing the NF‐κB inflammatory pathway

iMetaOmics, EarlyView.
Infectious bronchitis virus (IBV) represents a major threat to poultry production, with current control strategies offering limited protection. In this study, we demonstrate gut microbiome is a critical determinant of IBV resistance using fecal microbiota transplantation.
Ouyang Peng, Yufang Liu, Xuanci Wang, Yihui Huang, Yiqin Yang, Qixiang Kang, Rui Geng, Guangli Hu, Aiping Lv, Fangyu Hu, Yongbo Xia, Xin Luo, Jiamin Liao, Yihong He, Zhanpeng Kuang, Yunping Du, Yun Zhang, Chunyi Xue, Zongxi Han, Wen‐Jun Li, Lei Dong, Hao Zhang, Yongchang Cao   +22 more
wiley   +1 more source

Inhibition of influenza virus infection by garlic oil and juice in cell culture

JSFA reports, EarlyView.
Abstract Background Influenza virus infections are a significant global health and economic burden. Garlic (Allium sativum) has been proposed to have antimicrobial properties. Raw garlic consumption has been widely advocated on the internet to fight influenza by many public health agencies, information of which is easily accessible by the public. There
Carla Breen, Timothy Smith, Nick Diamantopoulos, Julie McAuley   +3 more
wiley   +1 more source

Systemic Governance From Below: Story Telling to Empower Access to the Commons Through Mapping and Modelling: A Mixed Methods Approach

Systems Research and Behavioral Science, EarlyView.
ABSTRACT Access to forests, farming land and the Citarum river is limited in Tarumajaya; furthermore, many do not own their own housing and are dependent on the public and private landowners in the area. The region of Tarumajaya faces significant challenges in access to crucial resources such as forests, farming land and the Citarum river, leading to a
Rudolf Wirawan, Janet Judy McIntyre‐Mills, R. Riswanda R. Riswanda, Ida Widianingsih, Indra Gunawan   +4 more
wiley   +1 more source

Prevalence of Eight Viruses in Captive Amur Tigers (Panthera tigris altaica) From Harbin, China 中国哈尔滨市圈养东北虎8种病毒的流行

Wildlife Letters, EarlyView.
The Amur tiger, an endangered flagship species mainly found in the Russia Far East and Northeastern China, holds immense biological importance, and has been listed under the Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES).
Wei Xie, Luyao Wang, Mengna Chen, Qinjie Chang, Hongyu Jiang, Haitao Xu, Liu Dan, Xiang Li, Yulong Wang, Xiangwei Zeng, Bin Yang, Miaowei Wang, Yonggang Jiang, Hongliang Chai, Siyuan Yang, Yajun Wang   +15 more
wiley   +1 more source

Newly identified properties of known pharmaceuticals and myxobacterial small molecules revealed by screening for autophagy modulators

The FEBS Journal, EarlyView.
Autophagy is a cellular degradation process involved in, for example, immune responses to pathogens and neurodegeneration. To identify modulators of autophagy, we developed a microscopy‐based screening assay and identified previously unknown autophagy‐modulating activities in known drugs and natural products from myxobacteria and fungi.
Janine Fichtner, Yan Yan Beer, H. G. Mauricio Ramm, Sabrina Mühlen, Frank Surup, Jennifer Herrmann, Toni Luise Meister, Stephanie Pfaender, Ursula Bilitewski, Mark Brönstrup, Rolf Müller, Manfred Wirth, Eeva‐Liisa Eskelinen, Ingo Schmitz   +13 more
wiley   +1 more source

Lung organoids as a human system for Mycobacteria infection modeling and drug testing

The FEBS Journal, EarlyView.
Mycobacterial infections, including tuberculosis (TB) and infections by nontuberculous mycobacteria (NTM), are still public health issues. In 2023, TB caused 1.25 million deaths, while NTM remain a clinical challenge for patients with cystic fibrosis (CF).
Stephen Adonai Leon‐Icaza, Romain Vergé, Raoul Mazars, Laurence Berry, Céline Cougoule   +4 more
wiley   +1 more source

SARS‐CoV‐2 nucleocapsid protein variants have differential RNA chaperone activity

The FEBS Journal, EarlyView.
The SARS‐CoV‐2 nucleocapsid (N) protein facilitates RNA annealing through its RBD–IDR2–CTD region, identifying it as a functional RNA chaperone. The Omicron BA.5 variant shows reduced chaperone activity compared to the Wuhan wild‐type protein. Although phosphorylation has no effect on wild‐type N, phosphomimetic modification of BA.5 N restores its RNA ...
Sabrina Babl, Julia M. Seidel, Fabian Kugler, Elisabeth Silberhorn, Anna Ludwig, Jonas Abel, Sophia Winklbauer, Niklas Schaub, Silvia Materna‐Reichelt, Kamran Honarnejad, Nataša Stojanović Gužvić, Gernot Längst   +11 more
wiley   +1 more source