Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
THE ROLE OF DIAGNOSIS OF CORPORATE CULTURE IN MERGER SCENARIOS
Вестник университета, 2016 The arguments substantiating the need for diagnosis of corporate culture in the planning of the merger are presented. The basic levels of the corporate culture development are identified.
M. Ermoshin
doaj
An analytical study of employee loyalty and corporate culture satisfaction assessment based on sentiment analysis. [PDF]
Front Psychol, 2022 Xie J, Su RLG, Song J.
europepmc +1 more source
Rationality, traditionalism and the state of corporate governance mechanisms: illustrations from a less developed country [PDF]
, 2008 Purpose ? The purpose of this research is to provide an account of corporate governance practices in Bangladesh. This paper demonstrates that the traditionalist culture mediates the rationalist/legalist framework of corporate governance in Bangladesh ...
Choudhury, J, Uddin, S
core
Membangun Paradigma Baru Hukum Perusahaan dan Etika Kewirausahaan [PDF]
, 2017 Curriculum of corporate law must be prepared to enter into the world of the industry with a very characteristic and distinctive, and the corporate law is not separated from the external business culture conditions develop.
Saliman, A. R. (Abdul) +1 more
core +2 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
THE ROLE OF DIAGNOSIS OF CORPORATE CULTURE IN MERGER SCENARIOS
Вестник университета, 2019 The arguments substantiating the need for diagnosis of corporate culture in the planning of the merger are presented. The basic levels of the corporate culture development are identified.
M. Ermoshin
doaj
Technology of formation and development of corporate culture of modern higher school
Ученые записки Российской академии предпринимательства, 2021 The paper presents an analysis of the social technologies of formation of corporate culture of higher education institutions. Defines the contentof the corporate culture as a set of several subcultures, the necessity of the algorithmic process of ...
N. G. Mustaeva
doaj
Research on Sustainable Development of Transport Infrastructure Based on Corporate Culture and Low-Carbon Perspective. [PDF]
J Environ Public Health, 2022 Fang W, Ma C, Lei Z.
europepmc +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source