Results 21 to 30 of about 207,810 (250)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Redesign Corporate Identity Sebagai Peningkatan Image Perusahaan Studi Kasus PT. Finansia Multi Finance [PDF]
The era of globalization brings two effects, on the one hand can increase the opportunities in the field of employment, on the other side of the business world increasingly keen competition and tight. Therefore, it needs the right strategy for success in
Kosasih, A. (Ade) +2 more
core
Work, consumption and subjectivity in postwar France: Moulinex and the meanings of domestic appliances, 1950s-1970s [PDF]
This article responds to some of the limitations of the historiography of consumption in contemporary Europe, notably its tendency to divorce consumer culture from production and to subscribe, in some cases at least, to a rather schematic model of ...
Clarke, J.
core +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Facial Recognition Attendance Monitoring System using Deep Learning Techniques
The Facial Recognition Attendance Monitoring System employing Deep Learning Techniques represents a cutting-edge application of artificial intelligence in educational and corporate environments.
M. A. Thalor, Omkar S. Gaikwad
semanticscholar +1 more source
2008-2009 Fordham Law School Faculty Bibliography [PDF]
https://ir.lawnet.fordham.edu/fac_bib/1011/thumbnail ...
Fordham Law School Library
core +1 more source
No equity, no triple aim: strategic proposals to advance health equity in a volatile policy environment [PDF]
Health professionals, including social workers, community health workers, public health workers, and licensed health care providers, share common interests and responsibilities in promoting health equity and improving social determinants of health—the ...
Acuff, C. +11 more
core +2 more sources
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source

