Results 101 to 110 of about 8,778,792 (221)

Tax management as function of integrated management by the registration and tax relations of the company

open access: yesПутеводитель предпринимателя, 2020
In given article theoretical questions of essence of corporate tax management are considered, the sequence of realization of activity of corporate tax management in life cycle of the company is represented as well as the structure of management of the ...

doaj  

Do institutional investor and group, firm and time effects matter in enterprise performance in the corporate life cycle?

open access: yesCogent Business & Management, 2019
Corporations undergo growth, maturity and decline, stages which form the corporate life cycle. This study discusses the influence of group, firm and time effects on enterprise performance variation at the different life cycle stages of Taiwan’s ...
Chiau-Shi Yang, Jonchi Shyu
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

CEO Power and Reclassification-Based Earnings Management Across Corporate Life Cycle Stages [PDF]

open access: yesPizhūhish/hā-yi ḥisābdārī-i mālī
CEO power plays a crucial role in a company's decision-making processes and can influence the use of classification shifting as a method of earnings management.
Mahdi Kazemioloum   +2 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Corporate Life Cycle, Corporate Governance and Corporate Social Responsibility Disclosure

open access: yesJurnal ASET (Akuntansi Riset)
This study examines the effect of CLC in the mature phase, size of the board of commissioners, size of the board of directors, and gender diversity on CSR disclosure with company size, profitability, slack, MTB, RnD, and company age as control variables. This study used 352 manufacturing companies listed on the IDX for 2019-2021.
Rahmawati, Rossy Azella, Kartika, Indri
openaire   +2 more sources

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Sustainability of Food Products Applying Integrated Life Cycle Tools [PDF]

open access: yes
The agri-food industry is a significant resource for the European economy. However, the competitiveness of this industry seems to be at risk due to its many structural problems (i.e.
Barbara Burchi, Angela Tarabella
core  

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