Results 81 to 90 of about 8,778,792 (221)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Energy, Sustainability and Society, 2019 Background Intellectual capital can not only help companies to obtain sustainable competitive advantage, but also serve as a key factor in corporate performance improvement and value creation.
Xin-long Xu, Cheng Kun Liu
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Determinants of credit to households in a life-cycle model [PDF]
This paper applies a life-cycle model with individual income uncertainty to investigate the determinants of credit to households. We show that the value of household credit to GDP ratio depends on (i) the lending-deposit interest rate spread, (ii ...
Dobromil Serwa, Michal Rubaszek
core +2 more sources
Human Source Domain in Metaphorizing Corporate Terminology
Cognitive Studies | Études cognitivesThis study attempts to apply the theory of conceptual metaphor to investigate the cognitive mechanism of metaphorisation in corporate terminology mapped from the human source domain.
Nguyen Thi Thuy Hanh
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
برنامهریزی و بودجه, 2021 This research examines the relationship between corporate social responsibility and financial constraints considering the life cycle and the role of moderating government-affiliated companies in the Tehran Stock Exchange.
Meysam Doaei, Amin Rohani
doaj
STAGES OF THE CULTURE ORGANIZATION DEVELOPMENT: AXIOLOGICAL ANALYSIS
Дискурс, 2017 The article considers the organization culture as a complex self-developing system that has its own life cycle and developmental features associated with passing of life cycle stages of the organization.
S. I. Tsareva
doaj +1 more source
Life cycle stages and corporate decisions
RAM. Revista de Administração MackenzieAbstract Purpose: This article aims to examine the influence of life cycle stages on the corporate decisions of Brazilian firms. Originality/value: The study contributes by presenting a scenario of investment, financing, dividend, and cash decisions, revealing patterns and characteristics of the evolution of Brazilian firms throughout their life ...
Marcelly Nóbrega de Medeiros +1 more
openaire +2 more sources