Results 81 to 90 of about 17,085 (296)

Sustainability of Food Products Applying Integrated Life Cycle Tools [PDF]

open access: yes
The agri-food industry is a significant resource for the European economy. However, the competitiveness of this industry seems to be at risk due to its many structural problems (i.e.
Barbara Burchi, Angela Tarabella
core  

Development of a life cycle cost estimating framework for oil refineries [PDF]

open access: yes, 2011
This study is concerned with the understanding of some vital features of various life cycle costing methodologies and tools. Integrating these features with the refinery technical processes would assist in the development of a life cycle costing ...
Okafor, Okechukwu Peter
core  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Factors for a successful sales forceduring the corporate life cycle [PDF]

open access: yes
The organisations, like all living organisms, have a lifecycle and undergo very predictable and repetitive patterns of behaviour as they grow and develop.
Felicia Adriana LUPU, Adrian Gelu LUPU
core  

CEO remuneration, financial distress and firm life cycle

open access: yes, 2023
This study investigates the association between CEO remuneration and firms' state of financial distress and whether that relationship varies systematically across firms' life cycle stages.
Taylor, Grantley   +9 more
core   +1 more source

Human Source Domain in Metaphorizing Corporate Terminology

open access: yesCognitive Studies | Études cognitives
This study attempts to apply the theory of conceptual metaphor to investigate the cognitive mechanism of metaphorisation in corporate terminology mapped from the human source domain.
Nguyen Thi Thuy Hanh
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Corporate Social Responsibility and Financial Constraints, Emphasizing the Life Cycle and the Moderating Role of Government-affiliated Companies

open access: yesبرنامه‌ریزی و بودجه, 2021
This research examines the relationship between corporate social responsibility and financial constraints considering the life cycle and the role of moderating government-affiliated companies in the Tehran Stock Exchange.
Meysam Doaei, Amin Rohani
doaj  

STAGES OF THE CULTURE ORGANIZATION DEVELOPMENT: AXIOLOGICAL ANALYSIS

open access: yesДискурс, 2017
The article considers the organization culture as a complex self-developing system that has its own life cycle and developmental features associated with passing of life cycle stages of the organization.
S. I. Tsareva
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

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