Results 41 to 50 of about 437,448 (305)

Cost of equity as the measuring instrument of risks during the corporate- and market life cycle [PDF]

open access: yes, 2013
Tato disertační práce se zabývá vztahem životního cyklu podniku a struktury podnikatelských rizik, která jsou měřena pomocí nákladů vlastního kapitálu. Kromě životního cyklu podniku je zohledněn i životní cyklus trhu.
Konečný, Zdeněk
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Product Life Cycles in Corporate Finance

open access: yesThe Review of Financial Studies, 2018
AbstractWe develop a novel 10-K text-based model of product life cycles and examine firm investment policies. Conditioning on the life cycle substantially improves the power of q to explain investment and reveals a natural ordering of investments over the life cycle.
Gerard Hoberg, Vojislav Maksimovic
openaire   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Rating the Raters: Evaluating how ESG Rating Agencies Integrate Sustainability Principles [PDF]

open access: yes, 2019
Environmental, social, and governance (ESG) rating agencies, acting as relevant financial market actors, should take a stand on working towards achieving a more sustainable development. In this context, the objective of this paper is, on the one hand, to
Escrig-Olmedo, Elena   +4 more
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The end of the corporate life cycle

open access: yesSSRN Electronic Journal, 2013
This paper asks how takeover and failure hazards change as listed firms get older. The hypothesis is that they increase because firms gradually run out of growth opportunities. We find the opposite. Both takeover and failure hazard drop significantly with age.
Loderer, Claudio, Wälchli, Urs
openaire   +5 more sources

Implicit tax dynamics and corporate life cycle: A quantitative analysis of B3 listed companies [PDF]

open access: yesRevista Contabilidade & Finanças
This study aims to analyze how implicit costs vary across the corporate life cycle stages (LCS) and determine whether companies retain the benefits of tax incentives despite the presence of implicit taxes.
Antonio Lopo Martinez   +2 more
doaj   +1 more source

Ensuring the strategic focus of a corporate project management system for commercial real estate

open access: yesНедвижимость: экономика, управление, 2021
Corporate trajectories ultimately determine economic growth or recession. They depend on the choice of development strategies selected for corporate management systems designated for commercial real estate projects. Strategic focusing tools of corporate
Roman Volkov, Didier Sinturele
doaj   +1 more source

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