Results 51 to 60 of about 437,448 (305)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Optimizing Risk Structure in Connection with the Corporate Life Cycle and Sector Cyclicity

open access: yesActa Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2016
Entrepreneurial activities and thus also investments are connected with two kinds of risks, namely with the operational and financial risk. Both of them are dependent especially on the corporate life cycle and on the sector sensitivity to the economic ...
Zdeněk Konečný, Marek Zinecker
doaj   +1 more source

Corporate cash management: A study on retail sector [PDF]

open access: yesAccounting, 2016
Cash is the life blood of the organizations and cash management is the important aspect of any organization. Corporate cash management boosts the companies from small to giant in the competitive environment. In this study, we highlighted three factors of
Somnath Das
doaj   +1 more source

Corporate Life Cycle, Corporate Governance and Corporate Social Responsibility Disclosure

open access: yesJurnal ASET (Akuntansi Riset)
This study examines the effect of CLC in the mature phase, size of the board of commissioners, size of the board of directors, and gender diversity on CSR disclosure with company size, profitability, slack, MTB, RnD, and company age as control variables. This study used 352 manufacturing companies listed on the IDX for 2019-2021.
Rahmawati, Rossy Azella, Kartika, Indri
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Classification of Corporate Cultures on Corporate Enterprises

open access: yesСоціальна економіка, 2019
The article is devoted to the classification of types of corporate cultures on the basis of the works of foreign researchers ‒ R. Harrison, T. Deal and A. Kennedy, V. Schneider, K. Cameron and R. Quinn, E.
Natalya Yaroshenko
doaj   +1 more source

Corporate Life Cycles and Analyst Recommendations

open access: yesJournal of Corporate Accounting & Finance
ABSTRACTThis study examines the relationship between firm life cycle stages and analyst recommendations. Using a dataset covering 1995 to 2022, we refine the sample to 62,731 firm‐year observations and employ established models to create proxies for the corporate life cycle stages.
al-Hadi, Ahmed Khamis   +1 more
openaire   +2 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Corporate life cycle methods in emerging markets: evidence from Turkey [PDF]

open access: yesPressacademia, 2017
Purpose - This paper focuses on the corporate life cycle concept which is one of the vital theories to analyze the firms more homogeneously. The aim of this study is to elaborate main life cycle classification procedures and to compare the most cited methodologies regarding financial indicators according to the expectations from the stages. Methodology
GULEC, Omer Faruk, KARACAER, Semra
openaire   +3 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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