Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
NEW PROBIOTIC AGENT FOR THE BOWEL MICROFLORA CORRECTION IN INFANTS
Вопросы современной педиатрии, 2013 Characteristics of a new probiotic — a biological additive, developed specially for children – and indications for its usage are shown in this article.
E. S. Keshishyan
doaj +1 more source
Correction to: A green energy research: forecasting of wind power for a cleaner environment using robust hybrid metaheuristic model [PDF]
, 2021 Alper Kerem, Ali Saygın, Rasoul Rahmani
openalex +1 more source
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Mass SARS-CoV-2 testing in US correctional facilities during the pandemic: a longitudinal analysis
BMJ Public HealthIntroduction Real-world evidence on the utility of SARS-CoV-2 mass screening in correctional facilities remains limited. The Connecticut Department of Correction (CTDOC) implemented an adaptive testing programme involving serial mass screening with ...
Albert I Ko +6 more
doaj +1 more source
Correction for Bjørgo et al., “Cross Talk between Phosphatidylinositol 3-Kinase and Cyclic AMP (cAMP)-Protein Kinase A Signaling Pathways at the Level of a Protein Kinase B/β-Arrestin/cAMP Phosphodiesterase 4 Complex” [PDF]
, 2022 Elisa Bjørgo +8 more
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Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Deformation Effect on the Center-of-Mass Correction Energy in Nuclei Ranging from Oxygen to Calcium [PDF]
, 2009 Zhao Peng-Wei, Sun Bao-Yuan, Meng Jie
openalex +1 more source