Results 101 to 110 of about 2,004,539 (278)

Features of cognitive functions in generalized anxiety disorder: narrative review

open access: yesEuropean Psychiatry
Introduction Generalized anxiety disorder (GAD) is characterized by excessive and uncontrollable worry and anxiety about several activities or events.
E. L. Isakulyan, M. P. Marachev
doaj   +1 more source

In Vivo Imaging of Intraocular Fluidics in Vitrectomized Swine Eyes Using a Digital Fluoroscopy System

open access: yesJournal of Ophthalmology, 2016
Purpose. To describe the characteristics of intraocular fluidics during cataract surgery in swine eyes with prior vitrectomy. Methods. We prepared three groups of enucleated swine eyes (nonvitrectomized, core, and totally vitrectomized).
Tamer Tandogan   +4 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Dynamic Stimulation Aberrometry

open access: yesOphthalmology Science
Purpose: Anterior iris-claw phakic intraocular lens (pIOL) implantation is a treatment option for refractive, ametropic patients. However, the postoperative accommodative ability has not been systematically researched.
Maximilian Hammer, MD   +2 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Psychological diagnostics of risky behavior of adolescents

open access: yesПсихіатрія, неврологія та медична психологія, 2020
The article reflects practical results of the research on adolescent risky behavior and specifically – the psychodiagnostics stage. Traditionally therapeutic impact on risky adolescents is not quite effective.
Anastasiia Rakhimkulova
doaj  

Herpes zoster ophthalmicus-induced oculomotor nerve palsy

open access: yesJournal of Optometry, 2013
Herpes zoster ophthalmicus (HZO) may cause a variety of ocular conditions including: dermatitis, corneal pseudo-dendrites, uveitis, retinitis, and cranial nerve palsies.
Jennifer S. Harthan   +1 more
doaj   +1 more source

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