Results 51 to 60 of about 4,680,147 (302)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

A deep-learning real-time bias correction method for significant wave height forecasts in the Western North Pacific [PDF]

, 2023
Wei Zhang, Yu Sun, Yapeng Wu, Junyu Dong, Xiaojiang Song, Zhiyi Gao, Renbo Pang, Boyu Guoan   +7 more
openalex   +1 more source

Correcting dispersion corrections with density-corrected DFT

Journal of Chemical Theory and Computation
Almost all empirical parameterizations of dispersion corrections in DFT use only energy errors, thereby mixing functional and density-driven errors. We introduce density and dispersion-corrected DFT (D2C-DFT), a dual-calibration approach that accounts for density delocalization errors when parametrizing dispersion interactions.
Minhyeok Lee, Byeongjae Kim, Mingyu Sim, Mihira Sogal, Youngsam Kim, Hayoung Yu, Kieron Burke, Eunji Sim   +7 more
openaire   +2 more sources

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

FEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue, Sandrine Picaud, Régine Hepp, Stéphanie Pons, Uwe Maskos, Bertrand Lambolez, Ludovic Tricoire   +6 more
wiley   +1 more source

Weak Interaction Rate Coulomb Corrections in Big Bang Nucleosynthesis

, 2009
We have applied a fully relativistic Coulomb wave correction to the weak reactions in the full Kawano/Wagoner Big Bang Nucleosynthesis (BBN) code. We have also added the zero temperature radiative correction.
A. deShalit, Christel J. Smith, George M. Fuller   +2 more
core   +1 more source

Laser-only adaptive optics achieves significant image quality gains compared to seeing-limited observations over the entire sky [PDF]

, 2017
Adaptive optics laser guide star systems perform atmospheric correction of stellar wavefronts in two parts: stellar tip-tilt and high-spatial-order laser-correction.
Baranec, Christoph, Howard, Ward S., Law, Nicholas M., Riddle, Reed, Ziegler, Carl A.   +4 more
core   +4 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Hybridization-related correction to the jellium model for fullerenes

, 2013
We introduce a new type of correction for a more accurate description of fullerenes within the spherically symmetric jellium model. This correction represents a pseudopotential which originates from the comparison between an accurate ab initio ...
A V Korol, A V Solov'yov, A V Verkhovtsev, Frisch M J, Kidun O, Madjet M E, Polozkov R G, R G Polozkov, Sattler K D, Solov'yov I A, V K Ivanov, Vieira A, Yabana K, Östling D   +13 more
core   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Core competency model self-directed violence prevention training program for corrections: a hybrid feasibility-effectiveness trial

BMC Public Health
Background Self-directed violence encompasses both suicide and self-injury. United States correctional settings face high self-directed violence rates.
Skyler D. Prowten, Sam C. Cacace, Jessamyn Moxie, Ava Peters, Adria Corral, Marvella Bowman, Lewis J. Peiper, Robert J. Cramer   +7 more
doaj   +1 more source