Results 51 to 60 of about 194,399 (303)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Analisis Maintenance Reliability Terhadap Mtbf (Mean Time Between Failures) Facilities Pada Industri Pulp & Paper [PDF]
, 2013 Penelitian ini dilakukan pada Fasilitas Mesin Robotyer sector Pulp Machine PT.Riau Andalan Pulp & Paper dan Bleaching Sector Pulp MAKING-9 PT. IndahKiat Pulp & Paper, bertujuan untuk mengetahui pengaruh MaintenanceReliability yang terdiri dari Preventive
Daniel, D. D. (Dian) +2 more
core
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Maintenance and Production Scheduling on a Single Machine with Stochastic Failures [PDF]
, 2015 In this paper we study the problem of determining a production schedule for an order of n jobs on a single machine which is subject to stochastic machine failures.
Kiesmüller, Gudrun P. +1 more
core
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Measuring the alignment of Maintenance and Manufacturing Strategies – The development of a new model and diagnostic tool [PDF]
, 2013 Purpose - To outline the development of a new conceptual model and diagnostic tool which assesses the strategic processes and links involved between maintenance and manufacturing strategies and the effect on manufacturing performance.
MacIntyre, John +2 more
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Investigating reliability centered maintenance (RCM) for public road mass transportation vehicles
MATEC Web of Conferences, 2016 Presently public road mass transportation organisations maintain their vehicles using scheduled corrective maintenance which is carried out at the discretion of the organisation.
Hopkinson James +2 more
doaj +1 more source
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source