Results 61 to 70 of about 4,147,721 (229)
A Touching and Contagious Captain Cook: Thinking History through Things [PDF]
, 2011 For how long can history, as it is conceived in ‘the West’, continue to attach itself to an exhausted humanism, where ‘man’ is central and all the natural and inanimate objects surrounding humans (and linked intimately to human activity) are relegated to
Muecke, Stephen
core +3 more sources
Synchronicity and Correlationism
, 2012 The name of Carl Gustav Jung tends not to be associated with a concern for philosophical realism, seen, as he is, as one of the worst apologists for obscurantism, mysticism and spiritualism of the modern age. Yet the thesis I try to defend here is that Jung’s work can be read as an elaborate attempt to escape the “correlationist circle” and the impasse
openaire +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Intraclass correlation – A discussion and demonstration of basic features
PLoS ONE, 2019 A re-analysis of intraclass correlation (ICC) theory is presented together with Monte Carlo simulations of ICC probability distributions. A partly revised and simplified theory of the single-score ICC is obtained, together with an alternative and simple ...
D. Liljequist +2 more
semanticscholar +1 more source
On the Internet Everybody Knows You’re a Whatchamacallit (or a Thing) [PDF]
, 2017 The Internet of Things (IoT) is fed by, and feeds into, flowing data streams. Through these flows, servers, sensors, humans and alike are networked together, data and networks mediating between physical and digital realms.
Coulton, Paul, Lindley, Joseph Galen
core
The Video Way of Thinking [PDF]
, 2018 This article rethinks the concepts of zoê and bios proposed by Giorgio Agamben in relation to the history of technology. It argues that the relationship between embodiment and the audiovisual is only beginning to be understood alongside the recent and ...
Spatz, Ben
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
"Spying for the People": surveillance, democracy and the impasse of cynical reason [PDF]
, 2018 This essay examines the Snowden affair as a sort of Rorschach test that traces the contours of what I am calling the impasse of cynical reason. In particular, I contend that the emerging form of algorithmic dataveillance both elicits and actively thwarts
Kaplan, Michael
core +2 more sources
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source