Results 111 to 120 of about 1,203,995 (286)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Design of Laser Activated Antimicrobial Porous Tricalcium Phosphate-Hydroxyapatite Scaffolds for Orthopedic Applications

Journal of Functional Biomaterials
The field of bone tissue engineering is steadily being improved by novel experimental approaches. Nevertheless, microbial adhesion after scaffold implantation remains a limitation that could lead to the impairment of the regeneration process, or scaffold
Emil Filipov, Ridvan Yildiz, Anna Dikovska, Lamborghini Sotelo, Tharun Soma, Georgi Avdeev, Penka Terziyska, Silke Christiansen, Anne Leriche, Maria Helena Fernandes, Albena Daskalova   +10 more
doaj   +1 more source

Correlative Microscopy of Bone in Implant Osteointegration Studies

The Scientific World Journal, 2010
Routine morphological analyses usually include investigations by light microscopy (LM), scanning electron microscopy (SEM), and transmission electron microscopy (TEM).
Alessandra Triré, Désirée Martini, Ester Orsini, Marco Franchi, Viviana De Pasquale, Beatrice Bacchelli, Mario Raspanti, Alessandro Ruggeri, Vittoria Ottani   +8 more
doaj   +1 more source

Pattern Formation in Catalytic H₂ Oxidation on Rh: Zooming in by Correlative Microscopy. [PDF]

ACS Catal, 2022
Zeininger J, Winkler P, Raab M, Suchorski Y, Prieto MJ, Tănase LC, de Souza Caldas L, Tiwari A, Schmidt T, Stöger-Pollach M, Steiger-Thirsfeld A, Roldan Cuenya B, Rupprechter G.   +12 more
europepmc   +1 more source

Correlative light electron ion microscopy reveals in vivo localisation of bedaquiline in Mycobacterium tuberculosis-infected lungs.

, 2021
Correlative light, electron, and ion microscopy (CLEIM) offers huge potential to track the intracellular fate of antibiotics, with organelle-level resolution.
Haibo Jiang (574973), Daniel J Greenwood (8281539), Angela Rodgers (488199), Maximiliano G Gutierrez (8133912), Antony Fearns (9045272)   +4 more
core  

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Correlative Scanning Electron and Super-Resolution Structured Illumination Microscopy

Photonics
Correlative microscopy techniques are used for many different applications in the biological sciences because the comparison of different imaging methods allows researchers to gain more and often complementary information about their samples. Correlative
Joseph R. Hamilton, Summer K. Levis, Guy M. Hagen   +2 more
doaj   +1 more source

Nanoscale Features of Tunable Bacterial Outer Membrane Models Revealed by Correlative Microscopy. [PDF]

Langmuir, 2022
Bali K, Mohamed Z, Scheeder A, Pappa AM, Daniel S, Kaminski CF, Owens RM, Mela I.   +7 more
europepmc   +1 more source

Correlative cryo-fluorescence light microscopy and cryo-electron tomography of streptomyces

, 2014
Light microscopy and electron microscopy are complementary techniques that in a correlative approach enable identification and targeting of fluorescently labeled structures in situ for three-dimensional imaging at nanometer resolution.
MullerReichert, T., Willemse, J., Verkade, P., Celler, K., Koning, R.I., Bos, E., Wezel, G.P. van, Koster, A.J.   +7 more
core   +1 more source