Results 21 to 30 of about 2,048 (135)

Identifying and predicting the pathogenic effects of a novel variant inducing severe early onset MMA: a bioinformatics approach

Hereditas, 2023
Background Methylmalonic acidemia (MMA) is a rare metabolic disorder resulting from functional defects in methylmalonyl-CoA mutase. Mutations in the MMAB gene are responsible for the cblB type of vitamin B12-responsive MMA.
Fereshteh Maryami, Elham Rismani, Elham Davoudi-Dehaghani, Nasrin Khalesi, Fatemeh Zafarghandi Motlagh, Alireza Kordafshari, Saeed Talebi, Hamzeh Rahimi, Sirous Zeinali   +8 more
doaj   +1 more source

Examination of the Glycine Betaine-Dependent Methylotrophic Methanogenesis Pathway: Insights Into Anaerobic Quaternary Amine Methylotrophy

Frontiers in Microbiology, 2019
Recent studies indicate that environmentally abundant quaternary amines (QAs) are a primary source for methanogenesis, yet the catabolic enzymes are unknown.
Adam J. Creighbaum, Tomislav Ticak, Shrameeta Shinde, Xin Wang, Donald J. Ferguson, Donald J. Ferguson   +5 more
doaj   +1 more source

Axial Ligation and Redox Changes at the Cobalt Ion in Cobalamin Bound to Corrinoid Iron-Sulfur Protein (CoFeSP) or in Solution Characterized by XAS and DFT. [PDF]

PLoS ONE, 2016
A cobalamin (Cbl) cofactor in corrinoid iron-sulfur protein (CoFeSP) is the primary methyl group donor and acceptor in biological carbon oxide conversion along the reductive acetyl-CoA pathway.
Peer Schrapers, Stefan Mebs, Sebastian Goetzl, Sandra E Hennig, Holger Dau, Holger Dobbek, Michael Haumann   +6 more
doaj   +1 more source

Proteome adaptations of the organohalide-respiring Desulfitobacterium hafniense strain DCB-2 to various energy metabolisms

Frontiers in Microbiology, 2023
IntroductionDesulfitobacterium hafniense was isolated for its ability to use organohalogens as terminal electron acceptors via organohalide respiration (OHR). In contrast to obligate OHR bacteria, Desulfitobacterium spp.
Mathilde Stéphanie Willemin, Romain Hamelin, Florence Armand, Christof Holliger, Julien Maillard   +4 more
doaj   +1 more source

Functional Expression and Characterization of a Panel of Cobalt and Iron-Dependent Nitrile Hydratases

Molecules, 2020
Nitrile hydratases (NHase) catalyze the hydration of nitriles to the corresponding amides. We report on the heterologous expression of various nitrile hydratases.
Birgit Grill, Maximilian Glänzer, Helmut Schwab, Kerstin Steiner, Daniel Pienaar, Dean Brady, Kai Donsbach, Margit Winkler   +7 more
doaj   +1 more source

Comparison of recombinant human haptocorrin expressed in human embryonic kidney cells and native haptocorrin.

PLoS ONE, 2012
Haptocorrin (HC) is a circulating corrinoid binding protein with unclear function. In contrast to transcobalamin, the other transport protein in blood, HC is heavily glycosylated and binds a variety of cobalamin (Cbl) analogues. HC is present not only in
Evelyne Furger, Sergey N Fedosov, Dorte Launholt Lildballe, Robert Waibel, Roger Schibli, Ebba Nexo, Eliane Fischer   +6 more
doaj   +1 more source

Polyphenol Oxidase Activity on Guaiacyl and Syringyl Lignin Units

Angewandte Chemie, Volume 136, Issue 48, November 25, 2024.
The conversion of lignin‐derived guaiacyl (G) and syringyl (S) compounds into methoxy‐ortho‐diphenols through oxidative ortho‐hydroxylation and ortho‐demethoxylation reactions catalyzed by novel fungal polyphenol oxidases (PPOs) is presented. The formation of o‐diphenols rather than reactive quinones can be steered by the addition of a reductant. These
Caio de O. G. Silva, Peicheng Sun, Kristian Barrett, Mark G. Sanders, Willem J. H. van Berkel, Mirjam A. Kabel, Anne S. Meyer, Jane W. Agger   +7 more
wiley   +2 more sources

Microbes display broad diversity in cobamide preferences

mSystems
Cobamides, the vitamin B12 (cobalamin) family of cofactors, are used by most organisms but produced by only a fraction of prokaryotes, and are thus considered key shared nutrients among microbes.
Kenny C. Mok, Olga M. Sokolovskaya, Adam M. Deutschbauer, Hans K. Carlson, Michiko E. Taga   +4 more
doaj   +1 more source

A bacterial chloroform reductive dehalogenase: purification and biochemical characterization

Microbial Biotechnology, 2017
Summary We report herein the purification of a chloroform (CF)‐reducing enzyme, TmrA, from the membrane fraction of a strict anaerobe Dehalobacter sp. strain UNSWDHB to apparent homogeneity with an approximate 23‐fold increase in relative purity compared
Bat‐Erdene Jugder, Susanne Bohl, Helene Lebhar, Robert D. Healey, Mike Manefield, Christopher P. Marquis, Matthew Lee   +6 more
doaj   +1 more source

Pseudovitamin B12 producing Loigolactobacillus coryniformis enhances soy milk fermentation by Lactobacillus delbrueckii subsp. bulgaricus

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Fermenting soy milk with lactic acid bacteria is challenging. Generally, carbohydrates are added to enhance the acid production in soy milk. However, the yoghurt starter Lactobacillus delbrueckii subsp. bulgaricus did not succeed in fermenting soy milk supplemented with carbohydrates.
Harutoshi Tsuda, Kunihisa Iwai, Natsuki Hayashizaki   +2 more
wiley   +1 more source