Results 61 to 70 of about 452,151 (266)

Cognitive Fatigue, Sleep and Cortical Activity in Multiple Sclerosis Disease. A Behavioral, Polysomnographic and Functional Near-Infrared Spectroscopy Investigation

Frontiers in Human Neuroscience, 2018
Patients with multiple sclerosis (MS) disease frequently experience fatigue as their most debilitating symptom. Fatigue in MS partially refers to a cognitive component, cognitive fatigue (CF), characterized by a faster and stronger than usual development
Guillermo Borragán, Guillermo Borragán, Médhi Gilson, Médhi Gilson, Anne Atas, Anne Atas, Hichem Slama, Hichem Slama, Hichem Slama, Hichem Slama, Andreas Lysandropoulos, Melanie De Schepper, Melanie De Schepper, Philippe Peigneux, Philippe Peigneux   +14 more
doaj   +1 more source

Semantic Cortical Activation in Dyslexic Readers

Journal of Cognitive Neuroscience, 1999
AbstractThe combined temporal and spatial resolution of MEG (magnetoencephalography) was used to study whether the same brain areas are similarly engaged in reading comprehension in normal and developmentally dyslexic adults. To extract a semantically sensitive stage of brain activation we manipulated the appropriateness of sentence-ending words to the
Helenius, Päivi, Salmelin, Riitta, Service, Elisabet, Connolly, John F.   +3 more
openaire   +3 more sources

Cerebral activation in malformations of cortical development [PDF]

Brain, 1998
Malformations of cortical development (MCD) are an important aetiology of localization-related epilepsy. Previous MRI and [11C]flumazenil PET studies have demonstrated widespread structural and neuroreceptor abnormalities beyond the region of MCD that is visually apparent on MRI.
M P, Richardson, M J, Koepp, D J, Brooks, J T, Coull, P, Grasby, D R, Fish, J S, Duncan   +6 more
openaire   +2 more sources

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano, Giacomo Boffa, Maria Petracca, Marta Ponzano, Nicole Graziano, Claire Wigley, Claire Riley, Jonathan Howard, Pietro Bontempi, Sylvia Klineova, Fred Lublin, Matilde Inglese   +11 more
wiley   +1 more source

Patterned activity within the local cortical architecture

Frontiers in Neuroscience, 2010
The cerebral cortex is a vastly complex structure consisting of multiple distinct populations of neurons residing in functionally specialized cortical compartments.
Farran Briggs, W Martin Usrey
doaj   +1 more source

Effects of Cortical Cooling on Activity Across Layers of the Rat Barrel Cortex

Frontiers in Systems Neuroscience, 2020
Moderate cortical cooling is known to suppress slow oscillations and to evoke persistent cortical activity. However, the cooling-induced changes in electrical activity across cortical layers remain largely unknown.
Gulshat Burkhanova, Kseniya Chernova, Roustem Khazipov, Roustem Khazipov, Maxim Sheroziya   +4 more
doaj   +1 more source

Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown, Giulia Carli, Prabesh Kanel, Stiven Roytman, Jaimie Barr, Nicolaas I. Bohnen, Roger L. Albin   +6 more
wiley   +1 more source

Evaluating prefrontal changes in depression using functional near-infrared spectroscopy utilizing Stroop test: A comparison with healthy controls

Indian Journal of Psychiatry
Background: Functional near-infrared spectroscopy (fNIRS) is being increasingly utilized to visualize the brain areas involved in cognitive activity to understand the human brain better.
Rohit Verma, Ragul Ganesh, Shubham Narnoli, Panna Sharma, Neha P. Shrivastava, Ishita Dhyani, Sonali Singhal, Stuti Karna   +7 more
doaj   +1 more source