Results 211 to 220 of about 446,858 (263)

RNAi in the Rhizarian Phytopathogen Plasmodiophora brassicae: The Causal Agent of Clubroot Disease in Cruciferous Crops

open access: yesAdvanced Science, EarlyView.
This study uncovers an unusual RNAi pathway in the rhizarian pathogen Plasmodiophora brassicae. In the absence of Dicer, a Drosha‐like RNase III protein supports the biogenesis of predominant 21‐nt small RNAs, and two Argonaute proteins mediate small RNA‐guided silencing.
Xiong Zhang   +13 more
wiley   +1 more source

Gm26550 Modulates Learning and Memory by Increasing IGF1 mRNA Expression and Stability in Nrf2−/− Mice

open access: yesAdvanced Science, EarlyView.
The present study shows that Nrf2 directly binds to the Gm26550 promoter, thereby activating Gm26550 transcription and increasing its expression. Mechanistically, Gm26550 promotes IGF1 expression by functionally antagonizing miR‐26a‐5p‐mediated repression and sequestering the RBP KHSRP, thereby enhancing hippocampal neuronal synaptic plasticity and ...
Hongfang Wang   +12 more
wiley   +1 more source

Genome sequencing reveals CCDC88A variants in malformations of cortical development and immune dysfunction. [PDF]

open access: yesHum Mol Genet
Lehtonen J   +18 more
europepmc   +1 more source

Cathepsin B deficiency disrupts cortical development via PEG3, leading to depression-like behavior. [PDF]

open access: yesCommun Biol
Xie Z   +11 more
europepmc   +1 more source

Biallelic null RAB3GAP1 variants impair cortical development and autophagy in Warburg Micro syndrome: evidence from fetal brain tissue and patient fibroblasts. [PDF]

open access: yesActa Neuropathol Commun
Noël E   +10 more
europepmc   +1 more source

Prenatal sodium channel dysfunction in Dravet syndrome alters cortical development

open access: yes
Zourray C   +24 more
europepmc   +1 more source

HPDL is critical in human cortical development via regulation of mitochondrial functional properties

open access: yes
Baggiani M   +11 more
europepmc   +1 more source

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